Polymyalgia rheumatica and polymyalgia-like syndromes as adverse events following COVID-19 vaccines: working notes from a narrative review of published literature.

COVID-19 vaccines adverse events following immunization narrative review polymyalgia rheumatica

Journal

Reumatologia
ISSN: 0034-6233
Titre abrégé: Reumatologia
Pays: Poland
ID NLM: 20130190R

Informations de publication

Date de publication:
2022
Historique:
received: 02 02 2022
accepted: 24 03 2022
entrez: 5 7 2022
pubmed: 6 7 2022
medline: 6 7 2022
Statut: ppublish

Résumé

Since the 1990s, polymyalgia rheumatica (PMR) has been reported as a possible adverse event following immunization (AEFI). The aim of this narrative review is to provide an overview of PMR (and PMR-like syndromes) following the most common types of COVID-19 vaccines, namely mRNA (tozinameran and mRNA-1273) and adenovirus-vectored (ChAdOx1-S) vaccines. To date, published literature reports few cases of PMR as vaccine-linked AEFI. Yet Vigibase, the WHO pharmacovigilance database, reports a few hundred cases. Based on these data, we address the question whether PMR/PMR-like syndromes following COVID-19 vaccines can be a true adverse or a coincidental event, and discuss its possible pathogenetic mechanisms.

Identifiants

pubmed: 35782034
doi: 10.5114/reum.2022.115665
pii: 46889
pmc: PMC9238316
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

142-147

Informations de copyright

Copyright: © 2022 Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Ciro Manzo (C)

Azienda Sanitaria Locale Napoli 3 sud, Internal and Geriatric Medicine Department, Rheumatologic Outpatient Clinic, Sant'Agnello, Naples, Italy.

Alberto Castagna (A)

Azienda Sanitaria Provinciale Catanzaro, Primary Care Department, Soverato, Catanzaro, Italy.

Marco Isetta (M)

Central and North West London NHS Trust, England.

Classifications MeSH