The Instrumental Activities of Daily Living in Parkinson's Disease Patients Treated by Subthalamic Deep Brain Stimulation.
activities of daily living
cognition
deep brain stimulation
everyday abilities
subthalamic nucleus
Journal
Frontiers in aging neuroscience
ISSN: 1663-4365
Titre abrégé: Front Aging Neurosci
Pays: Switzerland
ID NLM: 101525824
Informations de publication
Date de publication:
2022
2022
Historique:
received:
28
02
2022
accepted:
30
05
2022
entrez:
5
7
2022
pubmed:
6
7
2022
medline:
6
7
2022
Statut:
epublish
Résumé
Everyday functioning and instrumental activities of daily living (IADL) play a vital role in preserving the quality of life in patients with Parkinson's disease (PD) after deep brain stimulation of the subthalamic nucleus (STN-DBS). The main goal of the current study was to examine IADL change in pre-and post-surgery of the STN-DBS. We also analyzed the influence of the levodopa equivalent daily dose (LEDD) and global cognitive performance (Dementia Rating Scale; DRS-2) as covariates in relation to IADL. Thirty-two non-demented PD patients were administered before and after STN-DBS neurosurgery the Penn Parkinson's Daily Activities Questionnaire (PDAQ; self-report), the DRS-2 and Beck Depression Inventory (BDI-II) to assess IADL change, global cognition, and depression. We found a positive effect of STN-DBS on IADL in the post-surgery phase. Moreover, lower global cognition and lower LEDD are predictive of lower IADL in both pre-surgery and post-surgery examinations. STN-DBS in PD is a safe method for improvement of everyday functioning and IADL. In the post-surgery phase, we show a relation of IADL to the severity of cognitive impairment in PD and to LEDD.
Sections du résumé
Background
UNASSIGNED
Everyday functioning and instrumental activities of daily living (IADL) play a vital role in preserving the quality of life in patients with Parkinson's disease (PD) after deep brain stimulation of the subthalamic nucleus (STN-DBS).
Objective
UNASSIGNED
The main goal of the current study was to examine IADL change in pre-and post-surgery of the STN-DBS. We also analyzed the influence of the levodopa equivalent daily dose (LEDD) and global cognitive performance (Dementia Rating Scale; DRS-2) as covariates in relation to IADL.
Methods
UNASSIGNED
Thirty-two non-demented PD patients were administered before and after STN-DBS neurosurgery the Penn Parkinson's Daily Activities Questionnaire (PDAQ; self-report), the DRS-2 and Beck Depression Inventory (BDI-II) to assess IADL change, global cognition, and depression.
Results
UNASSIGNED
We found a positive effect of STN-DBS on IADL in the post-surgery phase. Moreover, lower global cognition and lower LEDD are predictive of lower IADL in both pre-surgery and post-surgery examinations.
Summary/Conclusion
UNASSIGNED
STN-DBS in PD is a safe method for improvement of everyday functioning and IADL. In the post-surgery phase, we show a relation of IADL to the severity of cognitive impairment in PD and to LEDD.
Identifiants
pubmed: 35783142
doi: 10.3389/fnagi.2022.886491
pmc: PMC9247575
doi:
Types de publication
Journal Article
Langues
eng
Pagination
886491Informations de copyright
Copyright © 2022 Bezdicek, Mana, Růžička, Havlik, Fečíková, Uhrová, Růžička, Urgošík and Jech.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
J Int Neuropsychol Soc. 2012 Sep;18(5):787-98
pubmed: 22621995
Mov Disord. 2010 Jul 15;25(9):1170-6
pubmed: 20310053
Neurol Sci. 2021 May;42(5):1773-1783
pubmed: 33738665
Lancet Neurol. 2013 Jan;12(1):37-44
pubmed: 23168021
Health Qual Life Outcomes. 2010 Aug 30;8:91
pubmed: 20799993
N Engl J Med. 2006 Aug 31;355(9):896-908
pubmed: 16943402
Acta Neurol Scand. 2011 Jan;123(1):20-7
pubmed: 20199514
Neurology. 2004 Jul 13;63(1):153-5
pubmed: 15249627
Mov Disord. 2022 Feb;37(2):291-301
pubmed: 35112384
Am J Occup Ther. 2014 May-Jun;68(3):353-62
pubmed: 24797199
Mov Disord. 2010 Dec 15;25(16):2756-61
pubmed: 20939079
Parkinsonism Relat Disord. 2013 Mar;19(3):371-4
pubmed: 23231974
Arch Neurol. 2011 Feb;68(2):165
pubmed: 20937936
Mov Disord. 2010 Nov 15;25(15):2649-53
pubmed: 21069833
J Neurol Neurosurg Psychiatry. 2006 Oct;77(10):1136-42
pubmed: 16801351
Mov Disord Clin Pract. 2019 Dec 14;7(1):61-69
pubmed: 31970213
World Neurosurg. 2019 May;125:e552-e562
pubmed: 30716489
Mov Disord. 2017 Jul;32(7):1056-1065
pubmed: 28605056
Cureus. 2018 Oct 22;10(10):e3474
pubmed: 30648026
J Neuropsychol. 2020 Mar;14(1):69-84
pubmed: 30320954
N Engl J Med. 2014 Oct 9;371(15):1369-73
pubmed: 25197963
Neuropsychology. 2014 Mar;28(2):229-37
pubmed: 24417192
PLoS One. 2012;7(11):e49056
pubmed: 23145068
Mov Disord. 2015 Dec;30(14):1967-70
pubmed: 26779608
Neuropsychology. 2019 Feb;33(2):169-177
pubmed: 30451512
J Clin Exp Neuropsychol. 2020 Oct;42(8):867-879
pubmed: 33043797
Qual Life Res. 2013 Sep;22(7):1543-53
pubmed: 23070750
J Parkinsons Dis. 2021;11(3):1297-1308
pubmed: 34024781
Dement Geriatr Cogn Disord. 2015;39(5-6):303-11
pubmed: 25792240
Parkinsonism Relat Disord. 2016 Apr;25:21-6
pubmed: 26923524
Neurol Sci. 2022 Feb;43(2):1047-1054
pubmed: 34109514
Parkinsonism Relat Disord. 2013 Nov;19(11):986-90
pubmed: 23899743
Expert Rev Neurother. 2006 Nov;6(11):1695-705
pubmed: 17144783
Parkinsons Dis. 2018 Jun 3;2018:4328371
pubmed: 29971141
J Formos Med Assoc. 2015 Sep;114(9):835-41
pubmed: 24103710
Arch Clin Neuropsychol. 2018 May 1;33(3):365-374
pubmed: 29718080
J Int Neuropsychol Soc. 2021 Sep 06;:1-12
pubmed: 34486508
Clin Neurophysiol. 2006 May;117(5):1017-28
pubmed: 16516544
Annu Rev Neurosci. 2006;29:229-57
pubmed: 16776585
J Neurol Neurosurg Psychiatry. 1992 Mar;55(3):181-4
pubmed: 1564476
Arch Neurol. 2000 Jul;57(7):983-8
pubmed: 10891980
Arch Clin Neuropsychol. 1998 Oct;13(7):575-83
pubmed: 14590618
Mov Disord. 2016 Jan;31(1):126-34
pubmed: 26249849
Clin Neuropsychol. 2017 Aug - Oct;31(6-7):1231-1247
pubmed: 28276860
Mov Disord. 2007 Sep 15;22(12):1689-707; quiz 1837
pubmed: 17542011
Brain Commun. 2020 Jan 29;2(1):fcaa005
pubmed: 32954278
J Clin Exp Neuropsychol. 2013;35(9):926-33
pubmed: 24074137
Int J Psychiatry Clin Pract. 2020 Nov;24(4):371-379
pubmed: 32552177
Arch Rehabil Res Clin Transl. 2021 Jul 03;3(3):100138
pubmed: 34589688
Mov Disord Clin Pract. 2016 Jul 08;4(2):237-244
pubmed: 30363396
Mov Disord. 2012 Mar;27(3):349-56
pubmed: 22275317
Mov Disord. 2016 Oct;31(10):1455-1465
pubmed: 27193358
Cas Lek Cesk. 2011;150(4-5):223-8
pubmed: 21634199