Congenital Co-infections Among HIV-Exposed Infants Born to Mothers on Antiretroviral Treatment in the United States.
HIV
congenital
cytomegalovirus
hepatitis C
perinatal
pregnancy
toxoplasmosis
Journal
Frontiers in pediatrics
ISSN: 2296-2360
Titre abrégé: Front Pediatr
Pays: Switzerland
ID NLM: 101615492
Informations de publication
Date de publication:
2022
2022
Historique:
received:
11
03
2022
accepted:
24
05
2022
entrez:
5
7
2022
pubmed:
6
7
2022
medline:
6
7
2022
Statut:
epublish
Résumé
Many women living with HIV (WLHIV) are co-infected with cytomegalovirus (CMV), Retrospective review of infants of WLHIV born between 2009-2019. Mothers were screened for antibodies to CMV, The study included 264 infants from 255 pregnancies in 191 mothers. At delivery, the median (IQR) CD4 count was 569 (406-748) cells/mm In a US cohort of pregnant WLHIV on ART, we identified high maternal CMV seroprevalence and a high rate of congenital CMV infection. We did not identify any congenital or perinatal transmissions of
Sections du résumé
Background
UNASSIGNED
Many women living with HIV (WLHIV) are co-infected with cytomegalovirus (CMV),
Methods
UNASSIGNED
Retrospective review of infants of WLHIV born between 2009-2019. Mothers were screened for antibodies to CMV,
Results
UNASSIGNED
The study included 264 infants from 255 pregnancies in 191 mothers. At delivery, the median (IQR) CD4 count was 569 (406-748) cells/mm
Conclusions
UNASSIGNED
In a US cohort of pregnant WLHIV on ART, we identified high maternal CMV seroprevalence and a high rate of congenital CMV infection. We did not identify any congenital or perinatal transmissions of
Identifiants
pubmed: 35783327
doi: 10.3389/fped.2022.894627
pmc: PMC9243256
doi:
Types de publication
Journal Article
Langues
eng
Pagination
894627Informations de copyright
Copyright © 2022 Smith, Silveira, Crotteau, Garth, Canniff, Fetters, Lazarus, Capraro, Weinberg and the CHIP Perinatal Team.
Déclaration de conflit d'intérêts
AW receives research grants from Merck, GlaxoSmithKline and Janssen (moneys to University of Colorado) and personal fees from Merck, Seqirus and Curevo. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
J Infect Dis. 1998 Jun;177(6):1480-8
pubmed: 9607823
Clin Infect Dis. 2019 Nov 13;69(11):1888-1895
pubmed: 30689769
J Infect Dis. 2016 Mar 15;213(6):992-8
pubmed: 26518046
J Med Virol. 2016 Jun;88(6):1051-8
pubmed: 26519647
Front Immunol. 2016 May 23;7:199
pubmed: 27242802
Pediatr Infect Dis J. 1996 Dec;15(12):1102-6
pubmed: 8970220
Nat Rev Gastroenterol Hepatol. 2021 Feb;18(2):117-130
pubmed: 33046891
Matern Child Health J. 2016 Mar;20(3):550-5
pubmed: 26520159
Clin Infect Dis. 2020 Mar 17;70(7):1379-1384
pubmed: 31102409
Reprod Health. 2011 Nov 30;8:35
pubmed: 22129112
Pediatr Infect Dis J. 2010 Oct;29(10):915-8
pubmed: 20431424
Rev Med Virol. 2007 Jul-Aug;17(4):253-76
pubmed: 17579921
Medicine (Baltimore). 2017 Feb;96(5):e6007
pubmed: 28151899
Clin Infect Dis. 1997 Nov;25(5):1121-4
pubmed: 9402369
J Biomed Inform. 2009 Apr;42(2):377-81
pubmed: 18929686
Clin Infect Dis. 2014 Sep 15;59(6):765-73
pubmed: 24928290
Braz J Infect Dis. 2014 Nov-Dec;18(6):609-17
pubmed: 25017666
J Med Virol. 1998 Feb;54(2):107-12
pubmed: 9496368
Eur J Obstet Gynecol Reprod Biol. 1996 Sep;68(1-2):93-6
pubmed: 8886688
J Med Virol. 2021 Nov;93(11):6393-6397
pubmed: 33475162
Clin Infect Dis. 2009 Jun 1;48(11):1516-25
pubmed: 19388872
PLoS One. 2014 Feb 24;9(2):e89857
pubmed: 24587077
Pediatrics. 2017 Feb;139(2):
pubmed: 28138010
Rev Med Virol. 2010 Jul;20(4):202-13
pubmed: 20564615
Eur J Clin Microbiol Infect Dis. 2020 Jun;39(6):1095-1102
pubmed: 31989374
Braz J Infect Dis. 2010 Mar-Apr;14(2):186-9
pubmed: 20563448
N Engl J Med. 1999 Jul 8;341(2):77-84
pubmed: 10395631
Pediatrics. 2017 Feb;139(2):
pubmed: 28049114
J Am Acad Audiol. 2000 May;11(5):283-90
pubmed: 10821506
Clin Infect Dis. 2012 Sep;55(6):877-84
pubmed: 22675157