Significantly higher frequencies of macrocytosis, anemia, serum vitamin B12 and folic acid deficiencies, and hyperhomocysteinemia in male than in female atrophic glossitis patients.
Atrophic glossitis
Folic acid
Hemoglobin
Homocysteine
Iron
Vitamin B12
Journal
Journal of dental sciences
ISSN: 2213-8862
Titre abrégé: J Dent Sci
Pays: Netherlands
ID NLM: 101293181
Informations de publication
Date de publication:
Jul 2022
Jul 2022
Historique:
received:
12
05
2022
revised:
16
05
2022
entrez:
5
7
2022
pubmed:
6
7
2022
medline:
6
7
2022
Statut:
ppublish
Résumé
Our previous study found that 19.0%, 16.9%, 5.3%, 2.3%, 11.9%, and 26.7% of 1064 atrophic glossitis (AG) patients have anemia, serum iron, vitamin B12, and folic acid deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity, respectively. This study evaluated the anemia, hematinic deficiencies, and hyperhomocysteinemia in 150 male and 914 female AG patients. The blood hemoglobin (Hb) and serum iron, vitamin B12, folic acid, homocysteine, GPCA levels in 150 male and 914 female AG patients were measured and compared with the corresponding levels in 75 male and 457 female healthy control subjects (HCSs), respectively. We found that 150 male AG patients had significantly lower mean blood Hb, serum iron, vitamin B12, and folic acid levels, and significantly higher mean serum homocysteine levels than 75 male HCSs. Moreover, 914 female AG patients had significantly lower mean blood Hb and serum iron levels and significantly higher mean serum homocysteine level than 457 female HCSs. In addition, 150 male AG patients had significantly higher mean blood Hb and serum homocysteine levels, significantly lower mean serum vitamin B12 and folic acid levels, and significantly higher frequencies of Hb, vitamin B12, and folic acid deficiency and hyperhomocysteinemia than 914 female AG patients. The male AG patients do have significantly higher mean blood Hb and serum homocysteine levels, significantly lower mean serum vitamin B12 and folic acid levels, and significantly higher frequencies of Hb, vitamin B12, and folic acid deficiencies and hyperhomocysteinemia than the female AG patients.
Sections du résumé
Background/purpose
UNASSIGNED
Our previous study found that 19.0%, 16.9%, 5.3%, 2.3%, 11.9%, and 26.7% of 1064 atrophic glossitis (AG) patients have anemia, serum iron, vitamin B12, and folic acid deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity, respectively. This study evaluated the anemia, hematinic deficiencies, and hyperhomocysteinemia in 150 male and 914 female AG patients.
Materials and methods
UNASSIGNED
The blood hemoglobin (Hb) and serum iron, vitamin B12, folic acid, homocysteine, GPCA levels in 150 male and 914 female AG patients were measured and compared with the corresponding levels in 75 male and 457 female healthy control subjects (HCSs), respectively.
Results
UNASSIGNED
We found that 150 male AG patients had significantly lower mean blood Hb, serum iron, vitamin B12, and folic acid levels, and significantly higher mean serum homocysteine levels than 75 male HCSs. Moreover, 914 female AG patients had significantly lower mean blood Hb and serum iron levels and significantly higher mean serum homocysteine level than 457 female HCSs. In addition, 150 male AG patients had significantly higher mean blood Hb and serum homocysteine levels, significantly lower mean serum vitamin B12 and folic acid levels, and significantly higher frequencies of Hb, vitamin B12, and folic acid deficiency and hyperhomocysteinemia than 914 female AG patients.
Conclusion
UNASSIGNED
The male AG patients do have significantly higher mean blood Hb and serum homocysteine levels, significantly lower mean serum vitamin B12 and folic acid levels, and significantly higher frequencies of Hb, vitamin B12, and folic acid deficiencies and hyperhomocysteinemia than the female AG patients.
Identifiants
pubmed: 35784143
doi: 10.1016/j.jds.2022.05.011
pii: S1991-7902(22)00105-2
pmc: PMC9236945
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1371-1377Informations de copyright
© 2022 Association for Dental Sciences of the Republic of China. Publishing services by Elsevier B.V.
Déclaration de conflit d'intérêts
The authors have no conflicts of interest relevant to this article.
Références
Lancet Neurol. 2007 Sep;6(9):830-8
pubmed: 17706567
J Formos Med Assoc. 2014 Feb;113(2):83-7
pubmed: 24388269
J Formos Med Assoc. 2019 Sep;118(9):1299-1307
pubmed: 31202497
J Endocrinol Invest. 2009 Sep;32(8):704-16
pubmed: 19494706
Am J Clin Nutr. 2007 Jan;85(1):193-200
pubmed: 17209196
J Oral Pathol Med. 2016 Jan;45(1):23-7
pubmed: 25990467
J Oral Pathol Med. 2013 Jul;42(6):474-9
pubmed: 23297780
J Dent Sci. 2020 Mar;15(1):42-49
pubmed: 32256999
J Dent Sci. 2021 Mar;16(2):608-613
pubmed: 33854709
J Dent Sci. 2020 Mar;15(1):34-41
pubmed: 32256998
J Natl Cancer Inst. 1999 Jul 21;91(14):1194-210
pubmed: 10413421
Am Fam Physician. 1997 May 15;55(7):2455-62
pubmed: 9166144
J Formos Med Assoc. 2020 Apr;119(4):813-820
pubmed: 31679908
J Oral Pathol Med. 2012 Jul;41(6):500-4
pubmed: 22188475
J Formos Med Assoc. 2020 Dec;119(12):1758-1763
pubmed: 32883568
J Dent Sci. 2021 Oct;16(4):1110-1116
pubmed: 34484577
Oral Dis. 2013 May;19(4):381-6
pubmed: 22957902
Oral Dis. 2013 Jul;19(5):519-24
pubmed: 23130817
Am J Clin Nutr. 1994 Oct;60(4):559-66
pubmed: 8092091
J Dent Sci. 2022 Jan;17(1):57-62
pubmed: 35028020
Exp Mol Med. 2021 Jan;53(1):125-135
pubmed: 33473144
Hematology Am Soc Hematol Educ Program. 2012;2012:183-90
pubmed: 23233579
Am Fam Physician. 2000 Nov 15;62(10):2255-64
pubmed: 11126852
J Oral Pathol Med. 2015 Mar;44(3):167-77
pubmed: 24527773
Food Nutr Bull. 2008 Jun;29(2 Suppl):S238-44
pubmed: 18709899
N Engl J Med. 2006 Apr 13;354(15):1567-77
pubmed: 16531613
Blood. 2009 Sep 10;114(11):2236-43
pubmed: 19561322
J Dent Sci. 2020 Jun;15(2):214-221
pubmed: 32595904
J Formos Med Assoc. 2020 Apr;119(4):774-780
pubmed: 31076315
J Formos Med Assoc. 2018 Dec;117(12):1065-1071
pubmed: 30087017
J Dent Sci. 2022 Jan;17(1):35-41
pubmed: 35028018
J Formos Med Assoc. 2017 Aug;116(8):613-619
pubmed: 28314600
J Formos Med Assoc. 2013 Dec;112(12):761-5
pubmed: 24139948
Int J Cell Cloning. 1986 May;4(3):139-66
pubmed: 3009649
Stem Cells. 1995 Jan;13(1):32-7
pubmed: 7719246
J Dent Sci. 2022 Jan;17(1):106-112
pubmed: 35028027
J Formos Med Assoc. 2020 Jun;119(6):1109-1115
pubmed: 31362840
J Formos Med Assoc. 2021 Feb;120(2):819-826
pubmed: 32888843
Endocrinology. 2012 Jul;153(7):3170-8
pubmed: 22535765
Blood Rev. 2014 Mar;28(2):49-66
pubmed: 24560123
J Formos Med Assoc. 2020 Jan;119(1 Pt 2):377-383
pubmed: 31277918
Blood Rev. 1989 Dec;3(4):211-5
pubmed: 2692743
Int J Cancer. 1992 Oct 21;52(4):566-9
pubmed: 1399138
J Dent Sci. 2021 Oct;16(4):1133-1139
pubmed: 34484580
J Formos Med Assoc. 2015 Aug;114(8):736-41
pubmed: 25935499
J Formos Med Assoc. 2020 Jan;119(1 Pt 3):544-552
pubmed: 31444017