StudyU: A Platform for Designing and Conducting Innovative Digital N-of-1 Trials.
N-of-1 trial
SCED
app
digital health
digital interventions
mobile application
single-case experimental design
web application
Journal
Journal of medical Internet research
ISSN: 1438-8871
Titre abrégé: J Med Internet Res
Pays: Canada
ID NLM: 100959882
Informations de publication
Date de publication:
05 07 2022
05 07 2022
Historique:
received:
21
12
2021
accepted:
18
04
2022
revised:
17
04
2022
entrez:
5
7
2022
pubmed:
6
7
2022
medline:
7
7
2022
Statut:
epublish
Résumé
N-of-1 trials are the gold standard study design to evaluate individual treatment effects and derive personalized treatment strategies. Digital tools have the potential to initiate a new era of N-of-1 trials in terms of scale and scope, but fully functional platforms are not yet available. Here, we present the open source StudyU platform, which includes the StudyU Designer and StudyU app. With the StudyU Designer, scientists are given a collaborative web application to digitally specify, publish, and conduct N-of-1 trials. The StudyU app is a smartphone app with innovative user-centric elements for participants to partake in trials published through the StudyU Designer to assess the effects of different interventions on their health. Thereby, the StudyU platform allows clinicians and researchers worldwide to easily design and conduct digital N-of-1 trials in a safe manner. We envision that StudyU can change the landscape of personalized treatments both for patients and healthy individuals, democratize and personalize evidence generation for self-optimization and medicine, and can be integrated in clinical practice.
Identifiants
pubmed: 35787512
pii: v24i7e35884
doi: 10.2196/35884
pmc: PMC9297132
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e35884Informations de copyright
©Stefan Konigorski, Sarah Wernicke, Tamara Slosarek, Alexander M Zenner, Nils Strelow, Darius F Ruether, Florian Henschel, Manisha Manaswini, Fabian Pottbäcker, Jonathan A Edelman, Babajide Owoyele, Matteo Danieletto, Eddye Golden, Micol Zweig, Girish N Nadkarni, Erwin Böttinger. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 05.07.2022.
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