Urethral and bladder neck stenosis after thulium laser enucleation of the prostate: Analysis of risk factors in a series of 1003 patients.
Aged
Constriction, Pathologic
/ epidemiology
Humans
Lasers
Male
Prostate
Prostatic Hyperplasia
/ etiology
Retrospective Studies
Risk Factors
Thulium
Transurethral Resection of Prostate
/ adverse effects
Treatment Outcome
Urethral Stricture
/ complications
Urinary Bladder
Urinary Bladder Neck Obstruction
/ epidemiology
ThuLEP
benign prostatic hyperplasia
bladder neck stenosis
postoperative complications
urethral stenosis
Journal
Andrologia
ISSN: 1439-0272
Titre abrégé: Andrologia
Pays: Germany
ID NLM: 0423506
Informations de publication
Date de publication:
Oct 2022
Oct 2022
Historique:
revised:
27
04
2022
received:
02
03
2022
accepted:
26
06
2022
pubmed:
6
7
2022
medline:
8
9
2022
entrez:
5
7
2022
Statut:
ppublish
Résumé
We assessed the incidence and risks factors of bladder neck and urethral stenosis after Thulium laser enucleation of the prostate. Patients who underwent surgery at two centres were retrospectively reviewed (December 2014-June 2020). Exclusion criteria: previous urethral/prostatic surgery, pelvic irradiation, prostate cancer, neurogenic bladder, history of bladder neck and urethral stenosis, concomitant transurethral surgery, active urinary tract infection. Significant variables at univariate analysis (p < 0.05) were included in a multivariate logistic regression analysis to establish their association with bladder neck/urethral stenosis. One thousand and three patients were included. Median age was 69.0 (63.0-75.0) years. Median prostate volume was 65.0 (46.3-82.0) ml. Median follow-up was 31 (25-75) months. Thirty patients (2.99%) developed bladder neck stenosis [median time after surgery: 15 (11-17.75) months], 50 patients (4.98%) urethral stenosis [median time after surgery: 9 (7-11) months]. Men with bladder neck and urethral stenosis had significantly smaller prostate volume (median volume 43.5 ml vs. 66.0 ml, p = 0.008, and 52.0 ml vs. 66.0 ml, p = 0.009, respectively). At multivariable analysis, short surgical time predicted for bladder neck stenosis (OR 0.973; 95% CI 0.957-0.994, p = 0.002), and re-catheterization (OR 3.956; 95% CI 1.867-8.382, p < 0.001) for urethral stenosis, whereas prostate volume was significantly associated with a lower incidence of US (OR 0.984, 95% CI 0.972-0.998, p = 0.03).
Substances chimiques
Thulium
8RKC5ATI4P
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e14523Informations de copyright
© 2022 Wiley-VCH GmbH.
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