Embryo morphology and live birth in the United States.
In vitro fertilization
blastocyst stage
cleavage stage
embryo morphology
live birth
Journal
F&S reports
ISSN: 2666-3341
Titre abrégé: F S Rep
Pays: United States
ID NLM: 101766618
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
received:
06
01
2022
revised:
17
02
2022
accepted:
18
02
2022
entrez:
5
7
2022
pubmed:
6
7
2022
medline:
6
7
2022
Statut:
epublish
Résumé
To determine the best-fit live birth rate per embryo based on maternal age, embryo stage, and embryo morphology. Retrospective data analysis. Fertility clinics. The patients included were treated with in vitro fertilization in the United States at clinics reporting data to the Society for Assisted Reproductive Technology Clinic Outcomes Reporting System. We analyzed live birth data of unbiopsied autologous cleavage and blastocyst stage embryos for cycles started from 2016 through 2018. The analysis included 223,377 embryo transfers with a total of 336,888 embryos. None. Live birth rate per embryo and rate of multiple gestations per pregnancy. At the mean maternal age of 34 years, fresh embryos produced live birth rates of 19%, 38%, 26%, and 27% for embryos aged 3, 5, 6, and 7 days, respectively. At the age 34 years, live birth rates for day 5 fresh embryos by overall morphology grade were 43% for good, 30% for fair, and 21% for poor. For the transfer of 2 fresh day 5 blastocysts, the rate of multiple gestations per pregnancy was 47% at 25 years old, 44% at 30 years old, 35% at 35 years old, and 23% at 40 years old. The analysis of pregnancy data in the Society for Assisted Reproductive Technology database can be used to calculate live birth rates per embryo based on maternal age, embryo age, and morphology. This information can be used for evidence-based decision making, quality control, and planning multicenter studies.
Identifiants
pubmed: 35789729
doi: 10.1016/j.xfre.2022.02.006
pii: S2666-3341(22)00015-0
pmc: PMC9250116
doi:
Types de publication
Journal Article
Langues
eng
Pagination
131-137Informations de copyright
© 2022 The Author(s).
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