Viral load of SARS-CoV-2 Omicron is not high despite its high infectivity.
COVID-19
Delta variant
Omicron variant
SARS-CoV-2
melting curve analysis
viral load
Journal
Journal of medical virology
ISSN: 1096-9071
Titre abrégé: J Med Virol
Pays: United States
ID NLM: 7705876
Informations de publication
Date de publication:
11 2022
11 2022
Historique:
revised:
29
06
2022
received:
23
05
2022
accepted:
03
07
2022
pubmed:
6
7
2022
medline:
15
9
2022
entrez:
5
7
2022
Statut:
ppublish
Résumé
Patients infected with the Omicron variant of severe acute respiratory syndrome coronavirus 2 has increased worldwide since the beginning of 2022 and the variant has spread more rapidly than the Delta variant, which spread in the summer of 2021. It is important to clarify the cause of the strong transmissibility of the Omicron variant to control its spread. In 694 patients with coronavirus disease 2019, the copy numbers of virus in nasopharyngeal swab-soaked samples and the viral genotypes were examined using quantitative polymerase chain reaction (PCR) and PCR-based melting curve analysis, respectively. Whole-genome sequencing was also performed to verify the viral genotyping data. There was no significant difference (p = 0.052) in the copy numbers between the Delta variant cases (median 1.5 × 10
Identifiants
pubmed: 35790476
doi: 10.1002/jmv.27974
pmc: PMC9349670
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
5543-5546Informations de copyright
© 2022 The Authors. Journal of Medical Virology published by Wiley Periodicals LLC.
Références
Nature. 2022 Apr;604(7906):553-556
pubmed: 35240676
J Med Virol. 2022 Apr;94(4):1707-1710
pubmed: 34825717
J Med Virol. 2022 Aug;94(8):3494-3497
pubmed: 35365865
Lancet. 2022 Apr 2;399(10332):1303-1312
pubmed: 35305296
Nature. 2022 Apr;604(7906):546-552
pubmed: 35228716
Nature. 2022 Mar;603(7902):679-686
pubmed: 35042229
J Med Virol. 2021 Dec;93(12):6833-6836
pubmed: 34314050
J Med Virol. 2022 Nov;94(11):5543-5546
pubmed: 35790476