β2-subunit alternative splicing stabilizes Cav2.3 Ca

Alternative Splicing Animals Dopaminergic Neurons Mesencephalon Mice Parkinson Disease / genetics Substantia Nigra / physiology
calcium channel blockers calcium channel modulation mouse mouse brain slices mouse midbrain dopamine neurons neuroscience voltage-gated calcium channels

Journal

eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614

Informations de publication

Date de publication:
06 07 2022
Historique:
received: 11 02 2021
accepted: 04 07 2022
pubmed: 7 7 2022
medline: 27 7 2022
entrez: 6 7 2022
Statut: epublish

Résumé

In dopaminergic (DA)

Identifiants

DOI: 10.7554/eLife.67464 PMID: 35792082 PMC: PMC9307272
pubmed: 35792082
doi: 10.7554/eLife.67464
pii: 67464
pmc: PMC9307272
doi:
pii:

Banques de données

GEO
['GSE114918']

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2022, Siller et al.

Déclaration de conflit d'intérêts

AS, DS, JD, CP, KV, EF, TS, PK, VC, EC The authors declare that they have no financial and non-financial competing interests, NH, GT, NB, SH, JB, AG, BL, NO, JS No competing interests declared

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Auteurs

Anita Siller (A)

Department of Pharmacology and Toxicology, Institute of Pharmacy, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria.

Nadja T Hofer (NT)

Department of Pharmacology and Toxicology, Institute of Pharmacy, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria.

Giulia Tomagra (G)

Department of Drug Science, NIS Centre, University of Torino, Torino, Italy.

Nicole Burkert (N)

Institute of Applied Physiology, University of Ulm, Ulm, Germany, Ulm, Germany.

Simon Hess (S)

Institute for Zoology, Biocenter, University of Cologne, Cologne, Germany.

Julia Benkert (J)

Institute of Applied Physiology, University of Ulm, Ulm, Germany, Ulm, Germany.

Aisylu Gaifullina (A)

Institute of Applied Physiology, University of Ulm, Ulm, Germany, Ulm, Germany.

Desiree Spaich (D)

Institute of Applied Physiology, University of Ulm, Ulm, Germany, Ulm, Germany.

Johanna Duda (J)

Institute of Applied Physiology, University of Ulm, Ulm, Germany, Ulm, Germany.

Christina Poetschke (C)

Institute of Applied Physiology, University of Ulm, Ulm, Germany, Ulm, Germany.

Kristina Vilusic (K)

Department of Pharmacology and Toxicology, Institute of Pharmacy, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria.

Eva Maria Fritz (EM)

Department of Pharmacology and Toxicology, Institute of Pharmacy, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria.

Toni Schneider (T)

Institute of Neurophysiology, University of Cologne, Cologne, Germany.

Peter Kloppenburg (P)

Institute for Zoology, Biocenter, University of Cologne, Cologne, Germany.
ORCID: 0000-0002-4554-404X

Birgit Liss (B)

Institute of Applied Physiology, University of Ulm, Ulm, Germany, Ulm, Germany.
Linacre College & New College, University of Oxford, Oxford, United Kingdom.

Valentina Carabelli (V)

Department of Drug Science, NIS Centre, University of Torino, Torino, Italy.

Emilio Carbone (E)

Department of Drug Science, NIS Centre, University of Torino, Torino, Italy.
ORCID: 0000-0003-2239-6280

Nadine Jasmin Ortner (NJ)

Department of Pharmacology and Toxicology, Institute of Pharmacy, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria.
ORCID: 0000-0003-3882-3283

Jörg Striessnig (J)

Department of Pharmacology and Toxicology, Institute of Pharmacy, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innsbruck, Austria.
ORCID: 0000-0002-9406-7120

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Classifications MeSH

questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Maturation post-transcriptionnelle des ARN › Épissage des ARN › Épissage alternatif › β2-subunit alternative splicing stabilizes Cav2.3 Ca
questionsmedicales.fr › Eucaryotes › Animaux › β2-subunit alternative splicing stabilizes Cav2.3 Ca
questionsmedicales.fr › Cellules › Neurones › Neurones dopaminergiques › β2-subunit alternative splicing stabilizes Cav2.3 Ca
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Tronc cérébral › Mésencéphale › β2-subunit alternative splicing stabilizes Cav2.3 Ca
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › β2-subunit alternative splicing stabilizes Cav2.3 Ca
questionsmedicales.fr › Maladies du système nerveux › Maladies neurodégénératives › Maladie de Parkinson › β2-subunit alternative splicing stabilizes Cav2.3 Ca
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Tronc cérébral › Mésencéphale › Pédoncule cérébral › Substantia nigra › β2-subunit alternative splicing stabilizes Cav2.3 Ca