Diversity in EWAS: current state, challenges, and solutions.
Journal
Genome medicine
ISSN: 1756-994X
Titre abrégé: Genome Med
Pays: England
ID NLM: 101475844
Informations de publication
Date de publication:
06 07 2022
06 07 2022
Historique:
received:
19
05
2022
accepted:
20
05
2022
entrez:
6
7
2022
pubmed:
7
7
2022
medline:
9
7
2022
Statut:
epublish
Résumé
Here, we report a lack of diversity in epigenome-wide association studies (EWAS) and DNA methylation (DNAm) data, discuss current challenges, and propose solutions for EWAS and DNAm research in diverse populations. The strategies we propose include fostering community involvement, new data generation, and cost-effective approaches such as locus-specific analysis and ancestry variable region analysis.
Identifiants
pubmed: 35794667
doi: 10.1186/s13073-022-01065-3
pii: 10.1186/s13073-022-01065-3
pmc: PMC9258042
doi:
Types de publication
Letter
Research Support, N.I.H., Extramural
Research Support, N.I.H., Intramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
71Informations de copyright
© 2022. The Author(s).
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