Daratumumab, Lenalidomide, and Dexamethasone (DRD), an Active Regimen in the Treatment of Immunosuppression-Associated Plasmablastic Lymphoma (PBL) in the Setting of Gorham's Lymphangiomatosis: Review of the Literature.
Journal
Case reports in hematology
ISSN: 2090-6560
Titre abrégé: Case Rep Hematol
Pays: United States
ID NLM: 101576456
Informations de publication
Date de publication:
2022
2022
Historique:
received:
11
10
2021
revised:
25
04
2022
accepted:
03
05
2022
entrez:
7
7
2022
pubmed:
8
7
2022
medline:
8
7
2022
Statut:
epublish
Résumé
Characterized by an aggressive course with a poor overall survival due to treatment refractoriness, plasmablastic lymphoma (PBL) is a rare variant of diffuse large cell B cell lymphoma. Gorham's lymphangiomatosis or Gorham-Stout disease (GSD) is a rare skeletal condition of unknown etiology characterized by progressive bone loss and nonmalignant proliferation of vascular and lymphatic channels within the affected bone. Neither disease has a standard of care. We present a 23-year-old HIV-negative woman with GSD, managed medically with octreotide and sirolimus, who developed PBL. After progressing on V-EPOCH (bortezomib, etoposide, vincristine, cyclophosphamide, doxorubicin, and prednisone), she was treated with daratumumab, lenalidomide, and dexamethasone (DRD) therapy and achieved complete remission after two cycles with progression after eight cycles. This is a report of treatment of PBL with DRD therapy. Clinical investigations of the DRD regimen in PBL in conjunction with other agents to improve both depth and durability of response are warranted.
Identifiants
pubmed: 35795542
doi: 10.1155/2022/8331766
pmc: PMC9252825
doi:
Types de publication
Case Reports
Langues
eng
Pagination
8331766Informations de copyright
Copyright © 2022 Matthew Lee et al.
Déclaration de conflit d'intérêts
The authors declare that there are no conflicts of interest.
Références
Leuk Res. 2011 Dec;35(12):1571-7
pubmed: 21752466
Oncol Res Treat. 2017;40(1-2):46-48
pubmed: 28095384
Front Immunol. 2021 Jul 12;12:702593
pubmed: 34322131
J Clin Oncol. 2013 Apr 20;31(12):e197-9
pubmed: 23509308
Clin Lymphoma Myeloma Leuk. 2011 Apr;11(2):185-9
pubmed: 21575922
Chest. 1994 Jan;105(1):208-13
pubmed: 8275732
Haematologica. 2016 Aug;101(8):976-84
pubmed: 27175027
J Clin Oncol. 2020 Nov 10;38(32):3794-3804
pubmed: 32701411
Mod Pathol. 2005 Jun;18(6):806-15
pubmed: 15578069
Ann Intern Med. 2007 Jan 2;146(1):75-6
pubmed: 17200231
Mod Pathol. 2017 Jan;30(1):85-94
pubmed: 27687004
Clin Case Rep. 2020 Dec 20;9(2):873-877
pubmed: 33598263
Am J Hematol. 2020 Nov;95(11):1344-1351
pubmed: 32777103
Clin Lymphoma Myeloma Leuk. 2019 Oct;19(10):e559-e563
pubmed: 31377210
JAAD Case Rep. 2020 Feb 12;6(3):161-165
pubmed: 32083160
BMJ Case Rep. 2020 Sep 29;13(9):
pubmed: 32994268
Iran Red Crescent Med J. 2014 Nov 17;16(11):e12180
pubmed: 25763205
Clin Lymphoma Myeloma Leuk. 2018 Jul;18(7):e275-e277
pubmed: 29753690
Oncol Res Treat. 2020;43(3):112-116
pubmed: 31842017
Clin Lymphoma Myeloma Leuk. 2021 Mar;21(3):e255-e263
pubmed: 33419717
Am J Surg Pathol. 2010 Nov;34(11):1686-94
pubmed: 20962620
Biol Blood Marrow Transplant. 2015 Jun;21(6):1146-7
pubmed: 25783635
Eur J Haematol. 2021 Apr;106(4):589-592
pubmed: 33469987
J Cell Biol. 2011 May 16;193(4):607-18
pubmed: 21576390
Blood. 2009 Sep 17;114(12):2564-6
pubmed: 19762505
Int J Hematol. 2016 Dec;104(6):669-681
pubmed: 27604616
Oncol Rep. 2015 Apr;33(4):1615-20
pubmed: 25695332
Medicine (Baltimore). 2021 Feb 19;100(7):e24498
pubmed: 33607779
Ann Hematol. 2017 Jun;96(6):967-970
pubmed: 28011983
J Hematol Oncol. 2009 Nov 12;2:47
pubmed: 19909553
Leuk Lymphoma. 2018 Sep;59(9):2121-2127
pubmed: 29303024
Korean J Radiol. 2002 Apr-Jun;3(2):130-2
pubmed: 12087203
J Bone Joint Surg Am. 1955 Oct;37-A(5):985-1004
pubmed: 13263344
Pediatr Blood Cancer. 2014 Mar;61(3):401-6
pubmed: 24214028
Biol Blood Marrow Transplant. 2014 Dec;20(12):1877-84
pubmed: 24946718
Am J Hematol. 2020 Jan;95(1):E28-E30
pubmed: 31725923
J Natl Compr Canc Netw. 2016 Sep;14(9):1067-79
pubmed: 27587620
Blood. 2011 May 12;117(19):5019-32
pubmed: 21300984
Br J Haematol. 2019 Feb;184(4):679-682
pubmed: 29527667
Blood. 2015 Apr 9;125(15):2323-30
pubmed: 25636338
N Engl J Med. 2016 Oct 6;375(14):1319-1331
pubmed: 27705267
Ann Oncol. 2017 Apr 1;28(4):843-848
pubmed: 28031174
BMJ Case Rep. 2020 Apr 6;13(4):
pubmed: 32265213