Distinct activities of Vδ1
Vδ1+ T-cells
allogeneic haematopoietic cell transplantation (alloHCT)
cytomegalovirus (CMV)
infection
γδ T-cells
Journal
Immunology
ISSN: 1365-2567
Titre abrégé: Immunology
Pays: England
ID NLM: 0374672
Informations de publication
Date de publication:
11 2022
11 2022
Historique:
received:
06
03
2022
accepted:
30
06
2022
pubmed:
8
7
2022
medline:
12
10
2022
entrez:
7
7
2022
Statut:
ppublish
Résumé
Cytomegalovirus (CMV) reactivation is the most frequent viral infectious complication correlating to non-relapse mortality after allogeneic haematopoietic cell transplantation (alloHCT). The intrinsic anti-CMV immunity has not been completely elucidated. γδ T-cells have drawn increasing attentions due to their distinct biological features and potential ability against viral infections. Previous studies reported a general association of γδ T-cells or Vδ2-negative γδ T-cells with CMV reactivation. Whereas researches for the direct responses and specific functions of γδ T subsets remain limited, especially in the scenario of alloHCT. Herein, we initially demonstrated that Vδ1
Substances chimiques
NK Cell Lectin-Like Receptor Subfamily K
0
Receptors, Antigen, T-Cell, gamma-delta
0
Toll-Like Receptor 2
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
368-383Informations de copyright
© 2022 John Wiley & Sons Ltd.
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