Docetaxel-loaded redox-sensitive nanoparticles self-assembling from poly(caprolactone) conjugates with disulfide-linked poly(ethylene glycol).
Docetaxel
anti-tumor activity
bio-security
glutathione
redox-sensitive
Journal
Journal of biomaterials science. Polymer edition
ISSN: 1568-5624
Titre abrégé: J Biomater Sci Polym Ed
Pays: England
ID NLM: 9007393
Informations de publication
Date de publication:
12 2022
12 2022
Historique:
pubmed:
8
7
2022
medline:
23
11
2022
entrez:
7
7
2022
Statut:
ppublish
Résumé
In this study, novel redox-sensitive nanoparticles (NPs) were fabricated from the poly(caprolactone) conjugates with disulfide-linked poly(ethylene glycol) (DDMAT- mPEG-S-S-PCL, DPSP). The DPSP polymer was synthesized by ring-opening polymerization (ROP) and reversible addition-fragmentation chain transfer (RAFT) polymerization. The obtaining of the DPSP polymer was confirmed by the
Identifiants
pubmed: 35796690
doi: 10.1080/09205063.2022.2099664
doi:
Substances chimiques
polycaprolactone
24980-41-4
Docetaxel
15H5577CQD
Disulfides
0
Drug Carriers
0
Antineoplastic Agents
0
Polyesters
0
methoxy poly(ethylene glycol-co-epsilon-caprolactone)
0
Polyethylene Glycols
3WJQ0SDW1A
caprolactone
56RE988L1R
Polymers
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM