Neutrophils in the tumor microenvironment and their functional modulation by mesenchymal stromal cells.
Mesenchymal stromal cells
Metastasis
Neutrophils
Tumor microenvironment
Journal
Cellular immunology
ISSN: 1090-2163
Titre abrégé: Cell Immunol
Pays: Netherlands
ID NLM: 1246405
Informations de publication
Date de publication:
09 2022
09 2022
Historique:
received:
11
04
2022
revised:
27
06
2022
accepted:
28
06
2022
pubmed:
8
7
2022
medline:
14
9
2022
entrez:
7
7
2022
Statut:
ppublish
Résumé
Neutrophils are the most predominant cell population in the innate immune system. The role of neutrophils in the initiation, development and metastasis of tumor has been actively studied in recent years. In cancer, neutrophils exert both pro- and anti-cancer effects, and their phenotype and function are affected by the tumor microenvironment (TME). This review aims to summarize the role of neutrophils in tumorigenesis with emphasis on their interaction with mesenchymal stromal cells (MSCs).
Identifiants
pubmed: 35797932
pii: S0008-8749(22)00101-0
doi: 10.1016/j.cellimm.2022.104576
pii:
doi:
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
104576Informations de copyright
Copyright © 2022 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.