Assay validity of point-of-care platelet function tests in thrombocytopenic blood samples.
flow cytometry
platelet function
point-of-care tests
thrombocytopenia
Journal
Biochemia medica
ISSN: 1846-7482
Titre abrégé: Biochem Med (Zagreb)
Pays: Croatia
ID NLM: 9610305
Informations de publication
Date de publication:
15 Jun 2022
15 Jun 2022
Historique:
received:
19
10
2021
accepted:
29
04
2022
entrez:
8
7
2022
pubmed:
9
7
2022
medline:
12
7
2022
Statut:
ppublish
Résumé
Point-of-care (POC) platelet function tests are faster and easier to perform than in-depth assessment by flow cytometry. At low platelet counts, however, POC tests are prone to assess platelet function incorrectly. Lower limits of platelet count required to obtain valid test results were defined and a testing method to facilitate comparability between different tests was established. We assessed platelet function in whole blood samples of healthy volunteers at decreasing platelet counts (> 100, 80-100, 50-80, 30-50 and < 30 x10 The minimal platelet count required for reliable test results was 100 x10 Calculating the ED
Identifiants
pubmed: 35799989
doi: 10.11613/BM.2022.020713
pii: bm-32-2-020713
pmc: PMC9195599
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
020713Informations de copyright
Croatian Society of Medical Biochemistry and Laboratory Medicine.
Déclaration de conflit d'intérêts
Potential conflict of interest None declared.
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