Long-Term Mortality After TAVI for Bicuspid vs. Tricuspid Aortic Stenosis: A Propensity-Matched Multicentre Cohort Study.

Patients with bicuspid aortic valve (BAV) stenosis were excluded from the pivotal trials of transcatheter aortic valve implantation (TAVI). We compared the in-hospital and long-term outcomes between patients undergoing TAVI for bicuspid and tricuspid aortic valve (TAV) stenosis. We performed a retrospective registry-based analysis on patients who underwent TAVI for BAV and TAV at five different centers between January 2009 and August 2017. The primary outcome was long-term all-cause mortality. Secondary outcomes were in-hospital mortality, procedural complications, and valve performance. Of 1,451 consecutive patients who underwent TAVI, two propensity-matched cohorts consisting of 130 patients with BAV and 390 patients with TAV were analyzed. All-cause mortality was comparable in both groups up to 10 years following TAVI ( Patients who had undergone TAVI for BAV had comparable mortality to patients with TAV up to 10 years after the procedure. The device success, in-hospital mortality, procedural complications, and PVL rate were comparable between the groups. The high rate of neurological complications (5%) in patients with BAV warrants further investigation.

Informations de copyright

Copyright © 2022 Gasecka, Walczewski, Witkowski, Dabrowski, Huczek, Wilimski, Ochała, Parma, Scisło, Rymuza, Zbroński, Szwed, Grygier, Olasińska-Wiśniewska, Jagielak, Targoński, Opolski and Kochman.

Déclaration de conflit d'intérêts

AW: proctor for Medtronic. ZH: proctor for Medtronic and Abbott. RP: lecture honoraria for Edwards Lifescience. MG: lecture honoraria, proctor and advisory board member of Boston Scientific. DJ: proctor for Edwards Lifesciences. JK: lecture honoraria and proctor for Medtronic, Boston Scientific, Abbott. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.