Psychosocial adaptation and influencing factors among patients with chemotherapy-induced peripheral neuropathy.

Cancer Chemotherapy-induced peripheral neuropathy Peripheral neurotoxicity Psychosocial adaptation Quality of life

Journal

World journal of clinical cases
ISSN: 2307-8960
Titre abrégé: World J Clin Cases
Pays: United States
ID NLM: 101618806

Informations de publication

Date de publication:
26 May 2022
Historique:
received: 11 12 2021
revised: 03 02 2022
accepted: 27 03 2022
entrez: 8 7 2022
pubmed: 9 7 2022
medline: 9 7 2022
Statut: ppublish

Résumé

Chemotherapy-induced peripheral neuropathy (CIPN) is a severe and long-lasting side effect caused by various anticancer agents that damage sensory, motor and autonomic nerves. It can cause maladaptive behaviors, including disease severity, anxiety, depression, sleep disorders, falls, and social impairment. These disorders have physical, psychological and social effects on patients and can seriously influence their quality of life. To investigate the current situation of psychosocial adaptation to the disease and its influencing factor in patients with CIPN. A convenience sampling method was used to select 233 patients with CIPN in our hospital from February to August 2021. In addition, a cross-sectional survey was conducted using a sociodemographic questionnaire, the Self-Report Psychosocial Adjustment to Illness Scale, and the European Organisation for the Research and Treatment of Cancer Quality of Life CIPN20 (QLQ-CIPN20). Factors influencing psychosocial adaptation in patients with CIPN were analyzed by The psychosocial adaptation score of patients with CIPN was 52.51 ± 13.18. Multivariate analysis showed that autonomic nerves, tumor stage, motor nerves, education level, availability of caregivers, semi-retirement status, CIPN grade were independent risk factors for patients with CIPN ( Patients with CIPN have poor psychosocial adaptation and are affected by a variety of physiological, psychological, and social factors. Patients' adaptive responses should be assessed, and targeted interventions implemented.

Sections du résumé

BACKGROUND BACKGROUND
Chemotherapy-induced peripheral neuropathy (CIPN) is a severe and long-lasting side effect caused by various anticancer agents that damage sensory, motor and autonomic nerves. It can cause maladaptive behaviors, including disease severity, anxiety, depression, sleep disorders, falls, and social impairment. These disorders have physical, psychological and social effects on patients and can seriously influence their quality of life.
AIM OBJECTIVE
To investigate the current situation of psychosocial adaptation to the disease and its influencing factor in patients with CIPN.
METHODS METHODS
A convenience sampling method was used to select 233 patients with CIPN in our hospital from February to August 2021. In addition, a cross-sectional survey was conducted using a sociodemographic questionnaire, the Self-Report Psychosocial Adjustment to Illness Scale, and the European Organisation for the Research and Treatment of Cancer Quality of Life CIPN20 (QLQ-CIPN20). Factors influencing psychosocial adaptation in patients with CIPN were analyzed by
RESULTS RESULTS
The psychosocial adaptation score of patients with CIPN was 52.51 ± 13.18. Multivariate analysis showed that autonomic nerves, tumor stage, motor nerves, education level, availability of caregivers, semi-retirement status, CIPN grade were independent risk factors for patients with CIPN (
CONCLUSION CONCLUSIONS
Patients with CIPN have poor psychosocial adaptation and are affected by a variety of physiological, psychological, and social factors. Patients' adaptive responses should be assessed, and targeted interventions implemented.

Identifiants

pubmed: 35801039
doi: 10.12998/wjcc.v10.i15.4843
pmc: PMC9198882
doi:

Types de publication

Journal Article

Langues

eng

Pagination

4843-4855

Informations de copyright

©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict-of-interest statement: The authors declared that no conflict of interest.

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Auteurs

Xiao Zhou (X)

Changzhou School of Clinical Medicine, Nanjing Medical University, Changzhou 213000, Jiangsu Province, China.

Dong-Yang Wang (DY)

Department of Nursing, School of Pharmacy, Changzhou University, Changzhou 213000, Jiangsu Province, China.

Cai-Yan Ding (CY)

Department of Nursing, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou 213000, Jiangsu Province, China.

Hui Liu (H)

School of Nursing, Bengbu Medical College, Bengbu 233000, Jiangsu Province, China.

Zhi-Qin Sun (ZQ)

Department of Nursing, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou 213000, Jiangsu Province, China. zqs1201@163.com.

Classifications MeSH