Increased Colocalization and Interaction Between Decidual Protein Kinase A and Insulin-like Growth Factor-Binding Protein-1 in Intrauterine Growth Restriction.

Cyclic AMP-Dependent Protein Kinases / metabolism Decidua Female Fetal Growth Retardation Humans Hypoxia / metabolism Insulin-Like Growth Factor Binding Protein 1 / metabolism Insulin-Like Growth Factor I / metabolism Pregnancy
fluorescent antibody technique humans hypoxia mass spectrometry maternal nutrient reduction papio placenta stromal cells

Journal

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
ISSN: 1551-5044
Titre abrégé: J Histochem Cytochem
Pays: United States
ID NLM: 9815334

Informations de publication

Date de publication:
07 2022
Historique:
pubmed: 9 7 2022
medline: 15 7 2022
entrez: 8 7 2022
Statut: ppublish

Résumé

Increased phosphorylation of decidual insulin-like growth factor-binding protein-1 (IGFBP-1) can contribute to intrauterine growth restriction (IUGR) by decreasing the bioavailability of insulin-like growth factor-1 (IGF-1). However, the molecular mechanisms regulating IGFBP-1 phosphorylation at the maternal-fetal interface are poorly understood. Protein kinase A (PKA) is required for normal decidualization. Consensus sequences for PKA are present in IGFBP-1. We hypothesized that the expression/interaction of PKA with decidual IGFBP-1 is increased in IUGR. Parallel reaction monitoring-mass spectrometry (PRM-MS) identified multiple PKA peptides (

Identifiants

DOI: 10.1369/00221554221112702 PMID: 35801847 PMC: PMC9284236
pubmed: 35801847
doi: 10.1369/00221554221112702
pmc: PMC9284236
doi:

Substances chimiques

IGFBP1 protein, human 0
Insulin-Like Growth Factor Binding Protein 1 0
Insulin-Like Growth Factor I 67763-96-6
Cyclic AMP-Dependent Protein Kinases EC 2.7.11.11

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

515-530

Subventions

Organisme : NICHD NIH HHS
ID : P01 HD021350
Pays : United States
Organisme : NICHD NIH HHS
ID : R01 HD089980
Pays : United States
Organisme : NICHD NIH HHS
ID : R03 HD078313
Pays : United States
Organisme : NIA NIH HHS
ID : U19 AG057758
Pays : United States

Références

Histochem Cell Biol. 2017 Mar;147(3):353-366
pubmed: 27774579
Vitam Horm. 2012;88:293-307
pubmed: 22391309
Mol Cell Endocrinol. 2021 Oct 1;536:111400
pubmed: 34314739
Am J Physiol Endocrinol Metab. 2020 Sep 1;319(3):E614-E628
pubmed: 32744097
J Clin Invest. 2002 Aug;110(3):411-8
pubmed: 12163461
J Biol Chem. 1991 Sep 25;266(27):18082-8
pubmed: 1655736
Mol Cell Endocrinol. 2020 Jul 15;512:110865
pubmed: 32502935
Endocrinology. 2004 May;145(5):2291-6
pubmed: 14726435
Mol Cell Endocrinol. 2017 Sep 5;452:1-14
pubmed: 28435049
Zentralbl Gynakol. 1999;121(12):587-90
pubmed: 10666868
J Clin Endocrinol Metab. 1997 Jun;82(6):1894-8
pubmed: 9177402
Mol Hum Reprod. 2006 May;12(5):309-19
pubmed: 16556676
Dis Markers. 2016;2016:7124186
pubmed: 26903689
Placenta. 2012 Apr;33(4):278-84
pubmed: 22265925
J Clin Endocrinol Metab. 2019 Feb 1;104(2):408-422
pubmed: 30124960
Endocrinology. 2014 Apr;155(4):1327-39
pubmed: 24437487
Front Pharmacol. 2015 Sep 15;6:202
pubmed: 26441659
Br J Nutr. 2013 Apr 28;109(8):1382-8
pubmed: 23046718
High Alt Med Biol. 2012 Sep;13(3):176-84
pubmed: 22994517
Mol Cell Endocrinol. 2016 Apr 15;425:48-60
pubmed: 26733150
J Histochem Cytochem. 2018 Sep;66(9):617-630
pubmed: 29718759
Am J Pathol. 2018 Jan;188(1):111-124
pubmed: 29037858
Mol Reprod Dev. 1993 Aug;35(4):368-74; discussion 374-5
pubmed: 7691098
Semin Reprod Med. 2007 Nov;25(6):445-53
pubmed: 17960529
Adv Anat Embryol Cell Biol. 2015;216:189-213
pubmed: 26450500
Prostaglandins. 1993 Aug;46(2):117-38
pubmed: 8210442
Biomolecules. 2021 Sep 18;11(9):
pubmed: 34572595
J Clin Endocrinol Metab. 1994 Dec;79(6):1735-41
pubmed: 7527409
Reprod Sci. 2012 Aug;19(8):883-94
pubmed: 22534328
Endocrinology. 2009 Jan;150(1):220-31
pubmed: 18772238
FASEB J. 2021 Sep;35(9):e21788
pubmed: 34425031
Horm Res. 2008;69(3):129-37
pubmed: 18219215
Placenta. 2011 Nov;32(11):845-51
pubmed: 21872927
Endocrinology. 1997 Mar;138(3):929-37
pubmed: 9048592
Proc Natl Acad Sci U S A. 1978 Oct;75(10):5034-8
pubmed: 368806
Biol Reprod. 1995 Mar;52(3):609-15
pubmed: 7756454
Growth Horm IGF Res. 1998 Feb;8(1):21-31
pubmed: 10990441
Mol Hum Reprod. 2001 Jan;7(1):79-87
pubmed: 11134364

Auteurs

Madhulika B Gupta (MB)

Department of Biochemistry and Department of Pediatrics, University of Western Ontario, London, ON, Canada.
Children's Health Research Institute, London, ON, Canada.

Kyle K Biggar (KK)

Institute of Biochemistry, Carleton University, Ottawa, ON, Canada.

Cun Li (C)

University of Wyoming, Laramie, Wyoming.

Peter W Nathanielsz (PW)

University of Wyoming, Laramie, Wyoming.
ORCID: 0000-0003-0802-0084

Thomas Jansson (T)

Southwest National Primate Research Center, San Antonio, Texas.
Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, Aurora, Colorado.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protein-Serine-Threonine Kinases › Cyclic Nucleotide-Regulated Protein Kinases › Cyclic AMP-Dependent Protein Kinases › Increased Colocalization and Interaction...
questionsmedicales.fr › Structures de l'embryon › Placenta › Caduques › Increased Colocalization and Interaction...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Troubles de la croissance › Retard de croissance intra-utérin › Increased Colocalization and Interaction...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Increased Colocalization and Interaction...
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Signes et symptômes respiratoires › Hypoxie › Increased Colocalization and Interaction...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de transport › Protéines de liaison aux IGF › Protéine-1 de liaison aux IGF › Increased Colocalization and Interaction...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Somatomédines › Facteur de croissance IGF-I › Increased Colocalization and Interaction...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Increased Colocalization and Interaction...