Pancreatic head sparing surgery for solid pseudopapillary tumor in patients with agenesis of the dorsal pancreas.
Journal
Journal of the Chinese Medical Association : JCMA
ISSN: 1728-7731
Titre abrégé: J Chin Med Assoc
Pays: Netherlands
ID NLM: 101174817
Informations de publication
Date de publication:
01 10 2022
01 10 2022
Historique:
pubmed:
9
7
2022
medline:
12
10
2022
entrez:
8
7
2022
Statut:
ppublish
Résumé
This study aimed to clarify the feasibility and justification of pancreatic head sparing (PHS) enucleation for patients with agenesis of the dorsal pancreas (ADP) associated with a solid pseudopapillary tumor (SPT). Data of the SPT patients with and without ADP, including clinical presentations, surgical options, and surgical and survival outcomes, were recruited for comparison. A total of 31 patients with SPTs were included, three of whom displayed ADP and underwent PHS enucleation. Surgical complications were comparable between the groups. Overall, the 5- and 10-year disease-free survival rates were 100% and 90%, respectively. The 20- and 25-year overall survival rates were 100% and 66.7%, respectively. Only one patient (3.2%) developed tumor recurrence 7.3 years after pancreatectomy for an SPT with lymph node involvement, and the patient survived 24.5 years after the initial operation. No tumor recurrence occurred in any patient with ADP after PHS enucleation. PHS enucleation seems to be feasible and justifiable for SPT patients with ADP in terms of surgical and survival outcomes, and this approach could be recommended to avoid pancreatic insufficiency.
Sections du résumé
BACKGROUND
This study aimed to clarify the feasibility and justification of pancreatic head sparing (PHS) enucleation for patients with agenesis of the dorsal pancreas (ADP) associated with a solid pseudopapillary tumor (SPT).
METHODS
Data of the SPT patients with and without ADP, including clinical presentations, surgical options, and surgical and survival outcomes, were recruited for comparison.
RESULTS
A total of 31 patients with SPTs were included, three of whom displayed ADP and underwent PHS enucleation. Surgical complications were comparable between the groups. Overall, the 5- and 10-year disease-free survival rates were 100% and 90%, respectively. The 20- and 25-year overall survival rates were 100% and 66.7%, respectively. Only one patient (3.2%) developed tumor recurrence 7.3 years after pancreatectomy for an SPT with lymph node involvement, and the patient survived 24.5 years after the initial operation. No tumor recurrence occurred in any patient with ADP after PHS enucleation.
CONCLUSION
PHS enucleation seems to be feasible and justifiable for SPT patients with ADP in terms of surgical and survival outcomes, and this approach could be recommended to avoid pancreatic insufficiency.
Identifiants
pubmed: 35801950
doi: 10.1097/JCMA.0000000000000771
pii: 02118582-202210000-00004
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
981-986Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2022, the Chinese Medical Association.
Déclaration de conflit d'intérêts
Conflicts of interest: The authors declare that they have no conflicts of interest related to the subject matter or materials discussed in this article.
Références
Robert AP, Iqbal S, John M. Complete agenesis of the dorsal pancreas: a rare clinical entity. Int J Appl Basic Med Res. 2016;6:290–2.
Mei W, Cao F, Li F. Two cases of agenesis of the dorsal pancreas and a review of the literature. BMC Gastroenterol. 2020;20:94.
Julianov AE, Saroglu AS. Pancreatic head cancer in a patient with complete agenesis of dorsal pancreas. Hepatobiliary Surg Nutr. 2019;8:327–8.
Erotokritou A, Gerharz CD, Sagir A. Agenesis of dorsal pancreas associated with pancreatic neuroendocrine tumor: a case report and review of the literature. J Med Case Rep. 2018;12:185.
Sannappa RM, Buragohain J, Sarma D, Saikia UK, Choudhury BK. Agenesis of dorsal pancreas associated with periampullary pancreaticobiliary type adenocarcinoma. JOP. 2014;15:489–92.
Sakpal SV, Sexcius L, Babel N, Chamberlain RS. Agenesis of the dorsal pancreas and its association with pancreatic tumors. Pancreas. 2009;38:367–73.
Hamoudi AB, Misugi K, Grosfeld JL, Reiner CB. Papillary epithelial neoplasm of pancreas in a child. Report of a case with electron microscopy. Cancer. 1970;26:1126–34.
Pant SR, Pokhrel NB, Chapagain P, Kansakar P. Different methods of resection of solid pseudopapillary neoplasm of the pancreas: a case series of three patients. Cureus. 2020;12:e7346.
Mahseeri M, Alqaiseieh A, Alkhader D, Halbony H, Albreazat M, Abualhaj S. Central pancreatectomy for solid pseudopapillary neoplasm: a pancreatic-preserving procedure. Int J Surg Case Rep. 2021;79:91–3.
Papavramidis T, Papavramidis S. Solid pseudopapillary tumors of the pancreas: review of 718 patients reported in English literature. J Am Coll Surg. 2005;200:965–72.
Bouassida M, Mighri MM, Bacha D, Chtourou MF, Touinsi H, Azzouz MM, et al. Solid pseudopapillary neoplasm of the pancreas in an old man: age does not matter. Pan Afr Med J. 2012;13:8.
Sanhueza CT, Huffman BM, Jin Z, Hartgers ML, Smyrk TC, Westin G, et al. Solid pseudopapillary neoplasms of the pancreas: a large American cohort. Pancreas. 2019;48:e21–2.
Lin X, Lin R, Lu F, Chen Y, Huang H. Surgical management of solid pseudopapillary neoplasms of pancreas: a single-center experience of 60 patients. Dig Surg. 2020;37:348–54.
Farhat W, Ammar H, Amine Said M, Mizouni A, Bouazzi A, Abdessaied N, et al. Solid pseudopapillary neoplasm of the pancreas: a report of 10 cases and literature review. ANZ J Surg. 2020;90:1683–8.
Bassi C, Marchegiani G, Dervenis C, Sarr M, Abu Hilal M, Adham M, et al.; International Study Group on Pancreatic Surgery (ISGPS). The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 Years after. Surgery. 2017;161:584–91.
Wente MN, Bassi C, Dervenis C, Fingerhut A, Gouma DJ, Izbicki JR, et al. Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS). Surgery. 2007;142:761–8.
Wente MN, Veit JA, Bassi C, Dervenis C, Fingerhut A, Gouma DJ, et al. Postpancreatectomy hemorrhage (PPH): an International Study Group of Pancreatic Surgery (ISGPS) definition. Surgery. 2007;142:20–5.
Besselink MG, van Rijssen LB, Bassi C, Dervenis C, Montorsi M, Adham M, et al.; International Study Group on Pancreatic Surgery. Definition and classification of chyle leak after pancreatic operation: a consensus statement by the International Study Group on Pancreatic Surgery. Surgery. 2017;161:365–72.
Clavien PA, Barkun J, de Oliveira ML, Vauthey JN, Dindo D, Schulick RD, et al. The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg. 2009;250:187–96.
Evans DB, Farnell MB, Lillemoe KD, Vollmer C Jr, Strasberg SM, Schulick RD. Surgical treatment of resectable and borderline resectable pancreas cancer: expert consensus statement. Ann Surg Oncol. 2009;16:1736–44.
Nakamura Y, Egami K, Maeda S, Hosone M, Onda M. Solid and papillary tumor of the pancreas complicating agenesis of the dorsal pancreas. J Hepatobiliary Pancreat Surg. 2001;8:485–9.
Nassif S, Ponchiardi C, Sachs T. Pancreatic neuroendocrine tumor in the setting of dorsal agenesis of the pancreas. Case Rep Gastrointest Med. 2016;2016:3801962.
Kapoor A, Singh R. Periampullary carcinoma in a patient with agenesis of dorsal pancreas. J Surg Case Rep. 2011;2011:4.
Ulusan S, Bal N, Kizilkilic O, Bolat F, Yildirim S, Yildirim T, et al. Case report: solid-pseudopapillary tumour of the pancreas associated with dorsal agenesis. Br J Radiol. 2005;78:441–3.
Liu M, Liu J, Hu Q, Xu W, Liu W, Zhang Z, et al. Management of solid pseudopapillary neoplasms of pancreas: a single center experience of 243 consecutive patients. Pancreatology. 2019;19:681–5.
Geers C, Moulin P, Pierre M, Gigot JF, Jean-François G, Weynand B, et al. Solid and pseudopapillary tumor of the pancreas–review and new insights into pathogenesis. Am J Surg Pathol. 2006;30:1243–9.
Kumar NAN, Bhandare MS, Chaudhari V, Sasi SP, Shrikhande SV. Analysis of 50 cases of solid pseudopapillary tumor of pancreas: aggressive surgical resection provides excellent outcomes. Eur J Surg Oncol. 2019;45:187–91.
Tjaden C, Hassenpflug M, Hinz U, Klaiber U, Klauss M, Büchler MW, et al. Outcome and prognosis after pancreatectomy in patients with solid pseudopapillary neoplasms. Pancreatology. 2019;19:699–709.
Wang X, Chen YH, Tan CL, Zhang H, Xiong JJ, Chen HY, et al. Enucleation of pancreatic solid pseudopapillary neoplasm: short-term and long-term outcomes from a 7-year large single-center experience. Eur J Surg Oncol. 2018;44:644–50.
Gao H, Gao Y, Yin L, Wang G, Wei J, Jiang K, et al. Risk factors of the recurrences of pancreatic solid pseudopapillary tumors: a systematic review and meta-analysis. J Cancer. 2018;9:1905–14.