Design, Synthesis, and Characterization of [

Animals Brain / diagnostic imaging Ligands Positron-Emission Tomography Radiopharmaceuticals Rats Rats, Sprague-Dawley Receptors, Metabotropic Glutamate / metabolism

Journal

Journal of medicinal chemistry
ISSN: 1520-4804
Titre abrégé: J Med Chem
Pays: United States
ID NLM: 9716531

Informations de publication

Date de publication:
28 07 2022
Historique:
pubmed: 9 7 2022
medline: 30 7 2022
entrez: 8 7 2022
Statut: ppublish

Résumé

An array of triazolopyridines based on JNJ-46356479 (

Identifiants

DOI: 10.1021/acs.jmedchem.2c00593 PMID: 35802702 PMC: PMC9434700
pubmed: 35802702
doi: 10.1021/acs.jmedchem.2c00593
pmc: PMC9434700
mid: NIHMS1831353
doi:

Substances chimiques

Ligands 0
Radiopharmaceuticals 0
Receptors, Metabotropic Glutamate 0
metabotropic glutamate receptor 2 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

9939-9954

Subventions

Organisme : NIBIB NIH HHS
ID : P41 EB022544
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS100164
Pays : United States
Organisme : NIH HHS
ID : S10 OD025234
Pays : United States
Organisme : NIBIB NIH HHS
ID : R01 EB021708
Pays : United States
Organisme : NIH HHS
ID : S10 OD018035
Pays : United States
Organisme : NCRR NIH HHS
ID : S10 RR023452
Pays : United States

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Auteurs

Gengyang Yuan (G)

Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.
ORCID: 0000-0003-4817-0052

Maeva Dhaynaut (M)

Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.

Nicolas J Guehl (NJ)

Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.
ORCID: 0000-0001-6876-8292

Sepideh Afshar (S)

Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.

Dalena Huynh (D)

Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.

Sung-Hyun Moon (SH)

Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.

Suhasini M Iyengar (SM)

Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.
ORCID: 0000-0002-1304-3021

Manish Kumar Jain (MK)

Department of Pharmacology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599, United States.
ORCID: 0000-0001-8173-3326

Julie E Pickett (JE)

Department of Pharmacology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599, United States.
ORCID: 0000-0002-9535-8528

Hye Jin Kang (HJ)

Department of Pharmacology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599, United States.

Mary Jo Ondrechen (MJ)

Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.
ORCID: 0000-0003-2456-4313

Georges El Fakhri (G)

Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.

Marc D Normandin (MD)

Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.

Anna-Liisa Brownell (AL)

Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.
ORCID: 0000-0002-3814-868X

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Design, Synthesis, and Characterization of [
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Design, Synthesis, and Characterization of [
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Ligands › Design, Synthesis, and Characterization of [
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › Design, Synthesis, and Characterization of [
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Radiopharmaceutiques › Design, Synthesis, and Characterization of [
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Design, Synthesis, and Characterization of [
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Rat Sprague-Dawley › Design, Synthesis, and Characterization of [
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs aux acides aminés › Récepteurs au glutamate › Récepteurs métabotropes au glutamate › Design, Synthesis, and Characterization of [