Prospective cohort study reveals unexpected aetiologies of livestock abortion in northern Tanzania.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
08 07 2022
08 07 2022
Historique:
received:
08
09
2021
accepted:
24
06
2022
entrez:
8
7
2022
pubmed:
9
7
2022
medline:
14
7
2022
Statut:
epublish
Résumé
Livestock abortion is an important cause of productivity losses worldwide and many infectious causes of abortion are zoonotic pathogens that impact on human health. Little is known about the relative importance of infectious causes of livestock abortion in Africa, including in subsistence farming communities that are critically dependent on livestock for food, income, and wellbeing. We conducted a prospective cohort study of livestock abortion, supported by cross-sectional serosurveillance, to determine aetiologies of livestock abortions in livestock in Tanzania. This approach generated several important findings including detection of a Rift Valley fever virus outbreak in cattle; high prevalence of C. burnetii infection in livestock; and the first report of Neospora caninum, Toxoplasma gondii, and pestiviruses associated with livestock abortion in Tanzania. Our approach provides a model for abortion surveillance in resource-limited settings. Our findings add substantially to current knowledge in sub-Saharan Africa, providing important evidence from which to prioritise disease interventions.
Identifiants
pubmed: 35803982
doi: 10.1038/s41598-022-15517-8
pii: 10.1038/s41598-022-15517-8
pmc: PMC9270399
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
11669Subventions
Organisme : Medical Research Council
ID : MC_UU_12014/10
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/L018926/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/J010367/1
Pays : United Kingdom
Organisme : FIC NIH HHS
ID : R01 TW009237
Pays : United States
Informations de copyright
© 2022. The Author(s).
Références
Vet J. 2019 Apr;246:12-20
pubmed: 30902184
PLoS Negl Trop Dis. 2021 Aug 24;15(8):e0009630
pubmed: 34428205
PLoS One. 2014 Mar 24;9(3):e91549
pubmed: 24662769
Trop Med Int Health. 2011 Jul;16(7):830-7
pubmed: 21470347
Vet Microbiol. 2009 Mar 16;135(1-2):38-45
pubmed: 18950964
PLoS Negl Trop Dis. 2019 Oct 17;13(10):e0007506
pubmed: 31622339
Mol Biol Evol. 2018 Jun 1;35(6):1547-1549
pubmed: 29722887
Vet World. 2017 Feb;10(2):194-208
pubmed: 28344403
J Dairy Sci. 2017 Nov;100(11):9215-9233
pubmed: 28843682
J Clin Microbiol. 2004 Mar;42(3):1290-3
pubmed: 15004098
Vet Microbiol. 2009 Mar 16;135(1-2):134-41
pubmed: 18930611
Trop Anim Health Prod. 2016 Feb;48(2):255-62
pubmed: 26526957
PLoS Negl Trop Dis. 2018 Jun 7;12(6):e0006444
pubmed: 29879104
Res Vet Sci. 2013 Jun;94(3):769-73
pubmed: 23261160
PLoS Negl Trop Dis. 2013 Jul 18;7(7):e2324
pubmed: 23875053
Theriogenology. 2008 Aug;70(3):270-85
pubmed: 18502494
Front Vet Sci. 2018 Oct 02;5:222
pubmed: 30333984
J Dairy Sci. 2013 Feb;96(2):877-88
pubmed: 23261379
Clin Infect Dis. 2011 Aug;53(4):e8-15
pubmed: 21810740
Vet Parasitol. 2006 Aug 31;140(1-2):1-34
pubmed: 16730126
PLoS One. 2017 Nov 15;12(11):e0188054
pubmed: 29141023
Res Vet Sci. 2002 Oct;73(2):187-9
pubmed: 12204640
J Comp Pathol. 1998 May;118(4):267-79
pubmed: 9651804
Onderstepoort J Vet Res. 2010 Aug 20;77(1):E1-5
pubmed: 23327157
Vet Clin North Am Food Anim Pract. 2016 Jul;32(2):425-41
pubmed: 27140298
Am J Trop Med Hyg. 2012 Dec;87(6):1105-11
pubmed: 23091197
Trop Anim Health Prod. 2013 Jan;45(1):211-7
pubmed: 22644734
Clin Microbiol Infect. 2011 Jan;17(1):34-43
pubmed: 20132255
BMC Res Notes. 2018 Feb 08;11(1):112
pubmed: 29422081
Vet Res. 2002 Mar-Apr;33(2):215-22
pubmed: 11944809
Acta Vet Scand. 2020 Jan 3;62(1):1
pubmed: 31900210
Acta Trop. 2019 May;193:99-105
pubmed: 30831112
Vector Borne Zoonotic Dis. 2012 Mar;12(3):189-91
pubmed: 22022809
Clin Infect Dis. 2017 Jun 15;64(suppl_3):S213-S227
pubmed: 28575370
Emerg Infect Dis. 2011 Apr;17(4):668-75
pubmed: 21470457
BMC Res Notes. 2012 Mar 19;5:152
pubmed: 22429653
J Comp Pathol. 2009 Jul;141(1):1-16
pubmed: 19476953
Parasit Vectors. 2015 Mar 18;8:166
pubmed: 25889004
Front Vet Sci. 2021 Jan 29;8:615310
pubmed: 33585619
Ann Rech Vet. 1990;21(4):267-73
pubmed: 2288452
J Gen Virol. 1997 Apr;78 ( Pt 4):725-35
pubmed: 9129644
Vet Res. 2018 Oct 17;49(1):106
pubmed: 30333061
Vet Parasitol. 2011 Aug 4;180(1-2):90-108
pubmed: 21704458
Sci Rep. 2020 Apr 27;10(1):7081
pubmed: 32341414
J S Afr Vet Assoc. 2013 Apr 19;84(1):E1-3
pubmed: 23718259
J Vet Diagn Invest. 2013 May;25(3):359-68
pubmed: 23572455
BMC Vet Res. 2018 Sep 3;14(1):271
pubmed: 30176865
Parasitology. 2013 Dec;140(14):1768-76
pubmed: 23953298
Front Vet Sci. 2020 Feb 14;7:65
pubmed: 32118078
Am J Trop Med Hyg. 2010 Aug;83(2 Suppl):58-64
pubmed: 20682907
Epidemiol Infect. 2019 Jan;147:e242
pubmed: 31364555
PLoS One. 2015 Jul 10;10(7):e0131873
pubmed: 26162089
Virol J. 2012 Sep 13;9:198
pubmed: 22973992
PLoS Negl Trop Dis. 2014 Apr 10;8(4):e2787
pubmed: 24722554
BMC Genomics. 2017 May 4;18(1):344
pubmed: 28472926
Tijdschr Diergeneeskd. 2012 Jul;137(7):450-7
pubmed: 22900421
Emerg Infect Dis. 2002 Feb;8(2):138-44
pubmed: 11897064
J Dairy Sci. 2006 Oct;89(10):3876-85
pubmed: 16960063
Onderstepoort J Vet Res. 2019 Aug 22;86(1):e1-e9
pubmed: 31478733
Am J Trop Med Hyg. 2020 Oct;103(4):1649-1655
pubmed: 32748778
J Gen Virol. 1997 Jun;78 ( Pt 6):1357-66
pubmed: 9191930
Diagn Microbiol Infect Dis. 2009 Jul;64(3):247-55
pubmed: 19395218
Vet Parasitol. 2012 Apr 30;185(2-4):91-100
pubmed: 22088616
Vet Res Commun. 2003 Jul;27(5):359-69
pubmed: 14509450
PLoS One. 2020 Dec 30;15(12):e0229478
pubmed: 33378382
Trends Parasitol. 2018 Feb;34(2):140-154
pubmed: 29174610
Front Vet Sci. 2019 Sep 26;6:327
pubmed: 31681800
Vet Parasitol. 2004 Sep 2;123(3-4):271-4
pubmed: 15325053
Epidemiol Infect. 1997 Feb;118(1):35-41
pubmed: 9042033
Mol Biol Evol. 1993 May;10(3):512-26
pubmed: 8336541
Int J Parasitol Parasites Wildl. 2018 Dec 24;8:111-117
pubmed: 30740303
Vet J. 2014 May;200(2):218-29
pubmed: 24709519
J Clin Microbiol. 2002 Jul;40(7):2323-30
pubmed: 12089242
Vet Parasitol. 2001 Dec 3;102(1-2):17-27
pubmed: 11705648
Parasitology. 2009 Dec;136(14):1887-94
pubmed: 19995468
BMC Vet Res. 2017 Dec 02;13(1):373
pubmed: 29197401
BMC Vet Res. 2019 Mar 18;15(1):95
pubmed: 30885192
Arch Virol. 2001;146(1):99-115
pubmed: 11266221
Am J Trop Med Hyg. 2010 Aug;83(2 Suppl):22-7
pubmed: 20682902
Korean J Parasitol. 2012 Mar;50(1):63-7
pubmed: 22451736
Transbound Emerg Dis. 2018 Apr;65(2):e329-e338
pubmed: 29120114
Front Public Health. 2019 Feb 19;7:25
pubmed: 30838195
J Vet Diagn Invest. 1993 Jan;5(1):64-8
pubmed: 8466983
Transbound Emerg Dis. 2018 Feb;65(1):e55-e62
pubmed: 28710814