Optimisation of the Green Process of Industrial Hemp-Preparation and Its Extract Characterisation.

WM-266-4 melanoma cells supercritical fluid extraction ultrasonic extraction

Journal

Plants (Basel, Switzerland)
ISSN: 2223-7747
Titre abrégé: Plants (Basel)
Pays: Switzerland
ID NLM: 101596181

Informations de publication

Date de publication:
30 Jun 2022
Historique:
received: 15 06 2022
revised: 27 06 2022
accepted: 28 06 2022
entrez: 9 7 2022
pubmed: 10 7 2022
medline: 10 7 2022
Statut: epublish

Résumé

Natural medicines and products are becoming increasingly important in the pharmaceutical and food industries. The most important step in obtaining a natural remedy is the processing of the natural material. This study offers the separation of the industrial hemp plant into fractions by mechanical treatment, which has a significant impact on the selectivity of the obtained fractions. This study also offers a solution to reduce waste by fractionating industrial hemp, focusing on the fraction with the highest cannabinoid content (49.5% of CBD). The study confirmed the anticancer potential of the extract, which prevents further division of WM-266-4 melanoma cells at a concentration of 10

Identifiants

pubmed: 35807701
pii: plants11131749
doi: 10.3390/plants11131749
pmc: PMC9269414
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Slovenian Research Agency
ID : P20046

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Auteurs

Taja Žitek (T)

Faculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova ul. 17, SI-2000 Maribor, Slovenia.

Petra Kotnik (P)

Faculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova ul. 17, SI-2000 Maribor, Slovenia.
Faculty of Medicine, University of Maribor, Taborska 8, SI-2000 Maribor, Slovenia.

Teo Makoter (T)

Faculty of Mechanical Engineering, University of Maribor, Smetanova ulica 17, SI-2000 Maribor, Slovenia.

Vesna Postružnik (V)

Faculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova ul. 17, SI-2000 Maribor, Slovenia.

Željko Knez (Ž)

Faculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova ul. 17, SI-2000 Maribor, Slovenia.
Faculty of Medicine, University of Maribor, Taborska 8, SI-2000 Maribor, Slovenia.

Maša Knez Marevci (M)

Faculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova ul. 17, SI-2000 Maribor, Slovenia.

Classifications MeSH