Microscopic colitis: lymphocytic colitis, collagenous colitis, and beyond.

Collagenous colitis Inflammatory bowel disease Lymphocytic colitis Microscopic colitis Microscopic colitis incomplete Pathology

Journal

Human pathology
ISSN: 1532-8392
Titre abrégé: Hum Pathol
Pays: United States
ID NLM: 9421547

Informations de publication

Date de publication:
02 2023
Historique:
received: 13 06 2022
revised: 27 06 2022
accepted: 30 06 2022
pubmed: 10 7 2022
medline: 7 2 2023
entrez: 9 7 2022
Statut: ppublish

Résumé

Microscopic colitis (MC) is a chronic inflammatory disease of colon with clinical presentations of chronic, watery, nonbloody diarrhea, and normal or almost normal endoscopic findings. Confirmation of a diagnosis of MC requires microscopic examination on colon biopsy to identify characteristic morphological features, in which 2 main subtypes of MC, lymphocytic colitis (LC) and collagenous colitis (CC), have been described. Although the pathogenesis of MC is still unclear, studies have revealed associations of MC with many risk factors and other diseases such as celiac disease, inflammatory bowel disease, and medication use. Meanwhile, variants of MC, MC incomplete, or MC-like changes in other conditions are still diagnostic dilemmas for pathologists. The goal of this paper is to systemically introduce the clinicopathologic features of MC and focus on unusual features of MC and its associations with other conditions.

Identifiants

pubmed: 35809686
pii: S0046-8177(22)00171-X
doi: 10.1016/j.humpath.2022.06.027
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

89-101

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Lin Yuan (L)

Pathology Center, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 201613, China.

Tsung-Teh Wu (TT)

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA.

Lizhi Zhang (L)

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA. Electronic address: Zhang.Lizhi@mayo.edu.

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Classifications MeSH