Changes in chorioretinal flow index after cataract surgery: an optical coherence tomography angiography study.
Cataract
Cystoid macular edema
OCT angiography
Pseudophakic
Journal
International ophthalmology
ISSN: 1573-2630
Titre abrégé: Int Ophthalmol
Pays: Netherlands
ID NLM: 7904294
Informations de publication
Date de publication:
Jan 2023
Jan 2023
Historique:
received:
09
11
2021
accepted:
14
06
2022
pubmed:
11
7
2022
medline:
9
2
2023
entrez:
10
7
2022
Statut:
ppublish
Résumé
Pseudophakic cystoid macular edema (CME) occurs in up to 2% of uneventful cataract surgeries. This study evaluates changes in macular blood flow succeeding uneventful phacoemulsification cataract extraction among otherwise visually healthy subjects. This prospective study included 18 eyes of 18 patients undergoing routine phacoemulsification. Optical coherence tomography angiography (OCT-A) was performed using the Angio-Retina 6 × 6 mm protocol with the XR Avanti Angio-Vue system (Optovue Inc., Fremont, California) prior to the surgery and 4-8 weeks thereafter. Exclusion criteria included motion artifacts, segmentation errors and signal strength index (SSI) < 40. The main outcome measure was change in flow index (FI) measured in all 4 retinal segmentation layers within an area of 1 mm diameter around the foveal center. Following surgery, a significant increase in SSI (46.65 ± 8.62 versus 53.12 ± 8.07, p = 0.01), superficial plexus FI (0.98 ± 0.23 versus 1.16 ± 0.16, p = 0.02) and deep plexus FI (0.54 ± 0.46 versus 0.93 ± 0.39, p = 0.01) was found. No significant changes were noted in the outer retina or the choriocapillaris. The study demonstrates a significant increase in FI in the superficial and deep retinal plexus following uneventful cataract surgery, with the greatest changes occurring in the latter. These findings corroborate evidence from structural imaging and support the vascular etiology of pseudophakic CME.
Identifiants
pubmed: 35810396
doi: 10.1007/s10792-022-02385-4
pii: 10.1007/s10792-022-02385-4
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
35-41Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer Nature B.V.
Références
Schein OD, Cassard SD, Tielsch JM, Gower EW (2012) Cataract surgery among medicare beneficiaries. Ophthalmic Epidemiol 19:257. https://doi.org/10.3109/09286586.2012.698692
doi: 10.3109/09286586.2012.698692
Qin VL, Conti FF, Singh RP (2018) Measuring outcomes in cataract surgery. Curr Opin Ophthalmol 29:100–104. https://doi.org/10.1097/ICU.0000000000000434
doi: 10.1097/ICU.0000000000000434
Yonekawa Y, Kim IK (2012) Pseudophakic cystoid macular edema. Curr Opin Ophthalmol 23:26–32. https://doi.org/10.1097/ICU.0B013E32834CD5F8
doi: 10.1097/ICU.0B013E32834CD5F8
Sigler EJ, Randolph JC, Kiernan DF (2016) Longitudinal analysis of the structural pattern of pseudophakic cystoid macular edema using multimodal imaging Graefes. Arch Clin Exp Ophthalmol 254:43–51. https://doi.org/10.1007/S00417-015-3000-8
doi: 10.1007/S00417-015-3000-8
Grzybowski A, Sikorski BL, Ascaso FJ, Huerva V (2016) Pseudophakic cystoid macular edema: update 2016. Clin Interv Aging 11:1221–1229. https://doi.org/10.2147/CIA.S111761
doi: 10.2147/CIA.S111761
Benitah NR, Arroyo JG (2010) Pseudophakic cystoid macular edema. Int Ophthalmol Clin 50:139–153. https://doi.org/10.1097/IIO.0B013E3181C551DA
doi: 10.1097/IIO.0B013E3181C551DA
The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery - PubMed. https://pubmed.ncbi.nlm.nih.gov/10360304/ . Accessed 18 Jul 2021
Anastasilakis K, Mourgela A, Symeonidis C et al (2015) Macular edema after uncomplicated cataract surgery: a role for phacoemulsification energy and vitreoretinal interface status? Eur J Ophthalmol 25:192–197. https://doi.org/10.5301/EJO.5000536
doi: 10.5301/EJO.5000536
Chaudhary C, Bahadhur H, Gupta N (2015) Study of cystoid macular edema by optical coherent tomography following uneventful cataract surgery. Int Ophthalmol 35:685–691. https://doi.org/10.1007/S10792-014-9998-5
doi: 10.1007/S10792-014-9998-5
Cheong KX, Tan CS (2015) Long-term increase in subfoveal choroidal thickness after surgery for senile cataracts. Am J Ophthalmol 159:608–609. https://doi.org/10.1016/J.AJO.2014.12.018
doi: 10.1016/J.AJO.2014.12.018
Ohsugi H, Ikuno Y, Ohara Z et al (2014) Changes in choroidal thickness after cataract surgery. J Cataract Refract Surg 40:184–191. https://doi.org/10.1016/J.JCRS.2013.07.036
doi: 10.1016/J.JCRS.2013.07.036
Pierru A, Carles M, Gastaud P, Baillif S (2014) Measurement of subfoveal choroidal thickness after cataract surgery in enhanced depth imaging optical coherence tomography Invest. Ophthalmol Vis Sci 55:4967–4974. https://doi.org/10.1167/IOVS.14-14172
doi: 10.1167/IOVS.14-14172
Kraff MC, Jampol LM, Sanders DR, Lieberman HL (1985) Factors affecting pseudophakic cystoid mascular edema: five randomized trials. J Am Intraocul Implant Soc 11:380–385. https://doi.org/10.1016/S0146-2776(85)80065-3
doi: 10.1016/S0146-2776(85)80065-3
Chen CL, Wang RK (2017) Optical coherence tomography based angiography [Invited]. Biomed Opt Express 8:1056. https://doi.org/10.1364/BOE.8.001056
doi: 10.1364/BOE.8.001056
Spaide RF, Curcio CA (2017) Evaluation of Segmentation of the Superficial and Deep Vascular Layers of the Retina by Optical Coherence Tomography Angiography Instruments in Normal Eyes. JAMA Ophthalmol 135:259–262. https://doi.org/10.1001/JAMAOPHTHALMOL.2016.5327
doi: 10.1001/JAMAOPHTHALMOL.2016.5327
AREDS study group and others (2001) The age-related eye disease study (AREDS) system for classifying cataracts from photographs: AREDS report no 4. Am J Ophthalmol 131:167–175. https://doi.org/10.1016/S0002-9394(00)00732-7
doi: 10.1016/S0002-9394(00)00732-7
Huang D, Jia Y, Gao SS et al (2016) Optical coherence tomography angiography using the optovue device. Dev Ophthalmol 56:6–12. https://doi.org/10.1159/000442770
doi: 10.1159/000442770
Zhao Z, Wen W, Jiang C, Lu Y (2018) Changes in macular vasculature after uncomplicated phacoemulsification surgery: Optical coherence tomography angiography study. J Cataract Refract Surg 44:453–458. https://doi.org/10.1016/J.JCRS.2018.02.014
doi: 10.1016/J.JCRS.2018.02.014
Jia Y, Tan O, Tokayer J et al (2012) Split-spectrum amplitude-decorrelation angiography with optical coherence tomography. Opt Express 20:4710. https://doi.org/10.1364/OE.20.004710
doi: 10.1364/OE.20.004710
Scarinci F, Nesper PL, Fawzi AA (2016) Deep retinal capillary nonperfusion is associated with photoreceptor disruption in diabetic macular Ischemia. Am J Ophthalmol 168:129–138. https://doi.org/10.1016/J.AJO.2016.05.002
doi: 10.1016/J.AJO.2016.05.002
Yu S, Frueh BE, Steinmair D et al (2018) Cataract significantly influences quantitative measurements on swept-source optical coherence tomography angiography imaging. PLoS ONE. https://doi.org/10.1371/JOURNAL.PONE.0204501
doi: 10.1371/JOURNAL.PONE.0204501
Pilotto E, Leonardi F, Stefanon G et al (2019) Early retinal and choroidal OCT and OCT angiography signs of inflammation after uncomplicated cataract surgery. Br J Ophthalmol 103:1001–1007. https://doi.org/10.1136/BJOPHTHALMOL-2018-312461
doi: 10.1136/BJOPHTHALMOL-2018-312461
Holló G, Aung T, Cantor LB, Aihara M (2020) Cystoid macular edema related to cataract surgery and topical prostaglandin analogs: Mechanism, diagnosis, and management. Surv Ophthalmol 65:496–512
doi: 10.1016/j.survophthal.2020.02.004
Wielders LH, Schouten JS, Winkens B et al (2018) European multicenter trial of the prevention of cystoid macular edema after cataract surgery in nondiabetics: ESCRS PREMED study report 1. J Cataract Refract Surg 44:429–439. https://doi.org/10.1016/J.JCRS.2018.01.029
doi: 10.1016/J.JCRS.2018.01.029