What's new in non-alcoholic fatty liver disease?
FATTY LIVER
FIBROSIS
Journal
Frontline gastroenterology
ISSN: 2041-4137
Titre abrégé: Frontline Gastroenterol
Pays: England
ID NLM: 101528589
Informations de publication
Date de publication:
2022
2022
Historique:
received:
14
04
2022
accepted:
20
05
2022
entrez:
11
7
2022
pubmed:
12
7
2022
medline:
12
7
2022
Statut:
epublish
Résumé
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver disease worldwide, with an estimated prevalence of 25% in the Western World. NAFLD is a broad spectrum of disease states and while most people with NAFLD do not have progressive disease, 10-20% of patients develop histological features of inflammation (non-alcoholic steatohepatitis), fibrosis, cirrhosis and its complications. Despite this large disease burden of significant clinical impact, most people living with NAFLD are undiagnosed, disease course prediction is imprecise and there are no treatments licensed for this condition. In this review, we discuss some of the recent developments in NAFLD, focusing on disease definition and diagnosis, risk stratification and treatments.
Identifiants
pubmed: 35812024
doi: 10.1136/flgastro-2022-102122
pii: flgastro-2022-102122
pmc: PMC9234732
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e102-e108Subventions
Organisme : Medical Research Council
ID : MR/T031883/1
Pays : United Kingdom
Informations de copyright
© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: WA has received fees for consulting and teaching or competitively awarded grant funding from Gilead Sciences, GlaxoSmithKline and AstraZeneca.
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