Multisite biologic tissue SARS-CoV-2 PCR testing in kidney transplantation from a COVID-positive donor.


Journal

Journal of surgical case reports
ISSN: 2042-8812
Titre abrégé: J Surg Case Rep
Pays: England
ID NLM: 101560169

Informations de publication

Date de publication:
Jul 2022
Historique:
received: 05 05 2022
revised: 09 06 2022
accepted: 10 06 2022
entrez: 11 7 2022
pubmed: 12 7 2022
medline: 12 7 2022
Statut: epublish

Résumé

With a high community transmission rate, SARS-CoV-2 has profoundly exacerbated the shortage of organs. Although the risk of donor-recipient transmission of SARS-CoV-2 is anecdotally low, an organ-specific infection analysis of procured organs from SARS-CoV-2 positive donors has yet to be established. Using a combination of clinically available and research-only polymerase chain reaction methods, organ preservation fluid and renal parenchymal tissues were tested for SARS-CoV-2 from the kidney of a SARS-CoV-2-positive donor prior to transplantation. The recipient has remained SARS-CoV-2 negative and clinically well, with excellent graft function 120 days post-transplantation.

Identifiants

pubmed: 35813455
doi: 10.1093/jscr/rjac314
pii: rjac314
pmc: PMC9258928
doi:

Types de publication

Case Reports

Langues

eng

Pagination

rjac314

Informations de copyright

Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2022.

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Auteurs

Jared R Zhang (JR)

UTMB, Department of Surgery, Division of Transplant Surgery, University Boulevard, Galveston, Texas, USA.

Michael Kueht (M)

UTMB, Department of Surgery, Division of Transplant Surgery, University Boulevard, Galveston, Texas, USA.

A Scott Lea (AS)

UTMB, Department of Medicine, Division of Infectious Diseases, University Boulevard, Galveston, Texas, USA.

Heather L Stevenson (HL)

UTMB, Department of Pathology, University Boulevard, Galveston, Texas, USA.

Joseph Gosnell (J)

UTMB, Department of Pathology, University Boulevard, Galveston, Texas, USA.

Ping Ren (P)

UTMB, Department of Pathology, University Boulevard, Galveston, Texas, USA.

Marisa C Nielsen (MC)

UTMB, Department of Pathology, University Boulevard, Galveston, Texas, USA.

Aaron Miller (A)

UTMB, Department of Pediatrics, Vaccinology, University Boulevard, Galveston, Texas, USA.

Muhammad Mujtaba (M)

UTMB, Department of Medicine, Division of Transplant Nephrology, University Boulevard, Galveston, Texas, USA.

Jeffrey Fair (J)

UTMB, Department of Surgery, Division of Transplant Surgery, University Boulevard, Galveston, Texas, USA.

Classifications MeSH