Multimodal imaging of experimental choroidal neovascularization.
choroidal neovascularization
fluorescein angiography
in vivo imaging
multicolor fundus imaging
optical coherence tomography angiography
Journal
International journal of ophthalmology
ISSN: 2222-3959
Titre abrégé: Int J Ophthalmol
Pays: China
ID NLM: 101553860
Informations de publication
Date de publication:
2022
2022
Historique:
received:
27
10
2021
accepted:
18
03
2022
entrez:
11
7
2022
pubmed:
12
7
2022
medline:
12
7
2022
Statut:
epublish
Résumé
To compare choroidal neovascularization (CNV) lesion measurements obtained by B6N.Cg-Tg(Csf1r-EGFP)1Hume/J heterozygous adult mice were subjected to laser-induced CNV and were monitored by fluorescein angiography (FA), multicolor (MC) fundus imaging and optical coherence tomography angiography (OCTA) at day 14 after CNV induction. Choroidal-retinal pigment epithelium (RPE) whole mounts were prepared at the end of the experiment and were stained with isolectin GS-IB4. CNV areas were measured in all different imaging modalities at day 14 after CNV from three independent raters and were compared to choroidal-RPE whole mounts. Intraclass correlation coefficient (ICC) type 2 (2-way random model) and its 95% confidence intervals (CI) were calculated to measure the correlation between different raters' measurements. Spearman's rank correlation coefficient (Spearman's FA (early and late) and MC correlates well with the CNV measurements This study suggests that FA and MC imaging could be used for the evaluation of CNV areas
Identifiants
pubmed: 35814883
doi: 10.18240/ijo.2022.06.05
pii: ijo-15-06-886
pmc: PMC9203475
doi:
Types de publication
Journal Article
Langues
eng
Pagination
886-893Informations de copyright
International Journal of Ophthalmology Press.
Références
Exp Eye Res. 1995 Jul;61(1):1-16
pubmed: 7556462
Transl Vis Sci Technol. 2019 Mar 27;8(2):8
pubmed: 30941265
Methods Mol Biol. 2021;2319:77-85
pubmed: 34331245
Retin Cases Brief Rep. 2015 Spring;9(2):97-101
pubmed: 25462132
Invest Ophthalmol Vis Sci. 2019 Apr 1;60(5):1556-1565
pubmed: 30995294
Proc Natl Acad Sci U S A. 2015 May 5;112(18):E2395-402
pubmed: 25897021
J Neuroinflammation. 2018 Dec 12;15(1):340
pubmed: 30541565
Am J Ophthalmol. 2014 Jul;158(1):171-178.e2
pubmed: 24631479
PLoS One. 2018 Aug 9;13(8):e0201958
pubmed: 30092067
Acta Med Litu. 2021;28(1):36-47
pubmed: 34393627
Retina. 2018 Sep;38(9):1751-1758
pubmed: 28834946
Int J Retina Vitreous. 2020 Nov 13;6(1):55
pubmed: 33292740
Sensors (Basel). 2021 Dec 21;22(1):
pubmed: 35009554
Int J Ophthalmol. 2021 Oct 18;14(10):1492-1500
pubmed: 34667724
Retina. 2015 Nov;35(11):2163-80
pubmed: 26428607
Int J Mol Sci. 2021 Nov 07;22(21):
pubmed: 34769482
Biomed Opt Express. 2015 Aug 25;6(9):3564-76
pubmed: 26417524
Graefes Arch Clin Exp Ophthalmol. 2018 Apr;256(4):643-649
pubmed: 29492687
Biomed Res Int. 2021 Nov 16;2021:1637377
pubmed: 34825001
Acta Ophthalmol. 2022 Jun;100(4):e936-e942
pubmed: 34407298
Invest Ophthalmol Vis Sci. 2013 Sep 27;54(9):6446-55
pubmed: 23989191
Br J Ophthalmol. 2015 Jun;99(6):842-7
pubmed: 25586715
Br J Ophthalmol. 2017 Jan;101(1):16-20
pubmed: 27707691
Exp Eye Res. 2016 Apr;145:417-423
pubmed: 26946073
Sci Rep. 2021 Oct 6;11(1):19903
pubmed: 34615975
Middle East Afr J Ophthalmol. 2021 Sep 25;28(2):87-92
pubmed: 34759665
JAMA Ophthalmol. 2015 Jan;133(1):45-50
pubmed: 25317632
Retina. 1998;18(1):30-6
pubmed: 9502278
Surv Ophthalmol. 2003 May-Jun;48(3):257-93
pubmed: 12745003
Graefes Arch Clin Exp Ophthalmol. 2014 May;252(5):715-21
pubmed: 24276561