Biogenic and facile synthesis of selenium nanoparticles using Vaccinium arctostaphylos L. fruit extract and anticancer activity against in vitro model of breast cancer.


Journal

Cell biology international
ISSN: 1095-8355
Titre abrégé: Cell Biol Int
Pays: England
ID NLM: 9307129

Informations de publication

Date de publication:
Oct 2022
Historique:
revised: 16 05 2022
received: 21 02 2022
accepted: 26 05 2022
pubmed: 13 7 2022
medline: 14 9 2022
entrez: 12 7 2022
Statut: ppublish

Résumé

Biogenic synthesis of selenium nanoparticles (SeNPs) using plant extracts has emerged as a promising alternative approach to traditional chemical synthesis. The current study aims to introduce a safe, low-cost, and green synthesis of SeNPs using fresh fruit extract of Vaccinium arctostaphylos L. The biogenic synthesis of SeNPs was confirmed by different analyses including ultraviolet-visible spectrophotometry, Fourier transform infrared, and energy-dispersive X-ray. Also, the crystalline nature, size, and morphology of the obtained SeNPs were characterized by X-ray diffraction, dynamic light scattering, field emission scanning electron microscopy, and transmission electron microscopy techniques. The SeNPs were successfully synthesized with fruit extract of V. arctostaphylos L. in a regular spherical form and narrow size distribution with suitable zeta-potential values and exhibited appropriate biocompatibility. It revealed that the synthesized SeNPs can significantly inhibit the growth of 4T1 breast cancer cells with an IC

Identifiants

pubmed: 35819083
doi: 10.1002/cbin.11852
doi:

Substances chimiques

Plant Extracts 0
Selenium H6241UJ22B

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1612-1624

Informations de copyright

© 2022 International Federation for Cell Biology.

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Auteurs

Mahmoud Gharbavi (M)

Nanotechnology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Mousa Mousavi (M)

Department of Horticultural Science, Faculty of Agriculture, Shahid Chamran University of Ahvaz, Ahvaz, Iran.

Mahsa Pour-Karim (M)

Pharmaceutical Biotechnology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.

Mahdi Tavakolizadeh (M)

Department of Pharmacognosy, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.

Ali Sharafi (A)

Pharmaceutical Biotechnology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.
School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.

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