School-based mindfulness training in early adolescence: what works, for whom and how in the MYRIAD trial?

adolescence implementation mediation mental health moderation preventive medicine process evaluation school-based mindfulness training

Journal

Evidence-based mental health
ISSN: 1468-960X
Titre abrégé: Evid Based Ment Health
Pays: England
ID NLM: 100883413

Informations de publication

Date de publication:
12 Jul 2022
Historique:
received: 03 02 2022
accepted: 16 05 2022
entrez: 12 7 2022
pubmed: 13 7 2022
medline: 13 7 2022
Statut: aheadofprint

Résumé

Preventing mental health problems in early adolescence is a priority. School-based mindfulness training (SBMT) is an approach with mixed evidence. To explore for whom SBMT does/does not work and what influences outcomes. The My Resilience in Adolescence was a parallel-group, cluster randomised controlled trial (K=84 secondary schools; n=8376 students, age: 11-13) recruiting schools that provided standard social-emotional learning. Schools were randomised 1:1 to continue this provision (control/teaching as usual (TAU)), and/or to offer SBMT ('.b' (intervention)). Risk of depression, social-emotional-behavioural functioning and well-being were measured at baseline, preintervention, post intervention and 1 year follow-up. Hypothesised moderators, implementation factors and mediators were analysed using mixed effects linear regressions, instrumental variable methods and path analysis. SBMT versus TAU resulted in worse scores on risk of depression and well-being in students at risk of mental health problems both at post intervention and 1-year follow-up, but differences were small and not clinically relevant. Higher dose and reach were associated with worse social-emotional-behavioural functioning at postintervention. No implementation factors were associated with outcomes at 1-year follow-up. Pregains-postgains in mindfulness skills and executive function predicted better outcomes at 1-year follow-up, but the SBMT was unsuccessful to teach these skills with clinical relevance.SBMT as delivered in this trial is not indicated as a universal intervention. Moreover, it may be contraindicated for students with existing/emerging mental health symptoms. Universal SBMT is not recommended in this format in early adolescence. Future research should explore social-emotional learning programmes adapted to the unique needs of young people.

Sections du résumé

BACKGROUND BACKGROUND
Preventing mental health problems in early adolescence is a priority. School-based mindfulness training (SBMT) is an approach with mixed evidence.
OBJECTIVES OBJECTIVE
To explore for whom SBMT does/does not work and what influences outcomes.
METHODS METHODS
The My Resilience in Adolescence was a parallel-group, cluster randomised controlled trial (K=84 secondary schools; n=8376 students, age: 11-13) recruiting schools that provided standard social-emotional learning. Schools were randomised 1:1 to continue this provision (control/teaching as usual (TAU)), and/or to offer SBMT ('.b' (intervention)). Risk of depression, social-emotional-behavioural functioning and well-being were measured at baseline, preintervention, post intervention and 1 year follow-up. Hypothesised moderators, implementation factors and mediators were analysed using mixed effects linear regressions, instrumental variable methods and path analysis.
FINDINGS RESULTS
SBMT versus TAU resulted in worse scores on risk of depression and well-being in students at risk of mental health problems both at post intervention and 1-year follow-up, but differences were small and not clinically relevant. Higher dose and reach were associated with worse social-emotional-behavioural functioning at postintervention. No implementation factors were associated with outcomes at 1-year follow-up. Pregains-postgains in mindfulness skills and executive function predicted better outcomes at 1-year follow-up, but the SBMT was unsuccessful to teach these skills with clinical relevance.SBMT as delivered in this trial is not indicated as a universal intervention. Moreover, it may be contraindicated for students with existing/emerging mental health symptoms.
CLINICAL IMPLICATIONS CONCLUSIONS
Universal SBMT is not recommended in this format in early adolescence. Future research should explore social-emotional learning programmes adapted to the unique needs of young people.

Identifiants

pubmed: 35820993
pii: ebmental-2022-300439
doi: 10.1136/ebmental-2022-300439
pmc: PMC9340034
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UU_00030/5
Pays : United Kingdom

Investigateurs

Saz Ahmed (S)
Louise Aukland (L)
Marc Bennett (M)
Triona Casey (T)
Nicola Dalrymple (N)
Eleanor-Rose Farley (ER)
Katie Fletcher (K)
Lucy Foulkes (L)
Kirsty Griffiths (K)
Cait Griffin (C)
Jennifer Harper (J)
Nils Kappelmann (N)
Maria Kempnich (M)
Konstantina Komninidou (K)
Rachel Knight (R)
Suzannah Laws (S)
Jovita Leung (J)
Emma Medlicott (E)
Lucy Palmer (L)
Jenna Parker (J)
Ariane Petit (A)
Alice Philips (A)
Blanca Piera Pi-Sunyer (BP)
Isobel Pryor-Nitsch (I)
Lucy Radley (L)
Jem Shackleford (J)
Ashok Sakhardande (A)
Elise Sellars (E)
Anna Sonley (A)
Alice Tickell (A)
Maris Vainre (M)
Lucy Warriner (L)
Brian Wainman (B)

Informations de copyright

© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: WK is the director of the Oxford Mindfulness Centre and receives royalties for several books on mindfulness. JMGW is former director of the Oxford Mindfulness Centre and receives royalties for several books on mindfulness.

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Auteurs

Jesus Montero-Marin (J)

Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Teaching, Reseach and Innovation Unit, Parc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, Spain.

Matthew Allwood (M)

Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.

Susan Ball (S)

NIHR Applied Research Collaboration (PenARC) South West Peninsula, University of Exeter, Exeter, UK.

Catherine Crane (C)

Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.

Katherine De Wilde (K)

Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.

Verena Hinze (V)

Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.

Benjamin Jones (B)

NIHR Applied Research Collaboration (PenARC) South West Peninsula, University of Exeter, Exeter, UK.

Liz Lord (L)

Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.

Elizabeth Nuthall (E)

Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.

Anam Raja (A)

Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.

Laura Taylor (L)

Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.

Kate Tudor (K)

Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.

Sarah-Jayne Blakemore (SJ)

Department of Psychology, University of Cambridge, Cambridge, UK.
UCL Institute of Cognitive Neuroscience, London, UK.

Sarah Byford (S)

King's College London, King's Health Economics, Institute of Psychiatry, Psychology and Neuroscience, De Crespigny Park, London, UK.

Tim Dalgleish (T)

Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.

Tamsin Ford (T)

Department of Psychiatry, University of Cambridge, Cambridge, UK.

Mark T Greenberg (MT)

Department of Human Development and Family Studies, Pennsylvania State University, University Park, Philadelphia, Pennsylvania, USA.

Obioha C Ukoumunne (OC)

NIHR Applied Research Collaboration (PenARC) South West Peninsula, University of Exeter, Exeter, UK.

J Mark G Williams (JMG)

Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.

Willem Kuyken (W)

Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK willem.kuyken@psych.ox.ac.uk.

Classifications MeSH