Distress Disorder Histories Relate to Greater Physical Symptoms Among Breast Cancer Patients and Survivors: Findings Across the Cancer Trajectory.


Journal

International journal of behavioral medicine
ISSN: 1532-7558
Titre abrégé: Int J Behav Med
Pays: England
ID NLM: 9421097

Informations de publication

Date de publication:
Aug 2023
Historique:
accepted: 07 07 2022
medline: 3 7 2023
pubmed: 14 7 2022
entrez: 13 7 2022
Statut: ppublish

Résumé

Psychological disorders can substantially worsen physical symptoms associated with breast cancer diagnosis and treatment, reducing survivors' quality of life and increasing recurrence risk. Distress disorders may be particularly detrimental given their physical correlates. Across two studies, we examined the relationship between a distress disorder history and physical symptoms pre- and post-adjuvant treatment - two important periods of the cancer trajectory. Breast cancer patients awaiting adjuvant treatment (n = 147; mean age = 52.54) in study 1 and survivors 1-10 years post-treatment (n = 183; mean age = 56.11) in study 2 completed a diagnostic interview assessing lifetime presence of psychological disorders. They also rated their pain, fatigue, physical functioning, and self-rated health. Covariates included body mass index, age, cancer stage, menopause status, and physical comorbidities. Results from both studies indicated that a distress disorder history was associated with higher pain, fatigue, and sleep difficulties as well as lower self-rated health compared to those without such a history. These findings suggest that breast cancer survivors with a distress disorder may be particularly at risk for more physical symptoms, poorer sleep, and worse self-rated health both prior to and following adjuvant treatment.

Sections du résumé

BACKGROUND BACKGROUND
Psychological disorders can substantially worsen physical symptoms associated with breast cancer diagnosis and treatment, reducing survivors' quality of life and increasing recurrence risk. Distress disorders may be particularly detrimental given their physical correlates. Across two studies, we examined the relationship between a distress disorder history and physical symptoms pre- and post-adjuvant treatment - two important periods of the cancer trajectory.
METHODS METHODS
Breast cancer patients awaiting adjuvant treatment (n = 147; mean age = 52.54) in study 1 and survivors 1-10 years post-treatment (n = 183; mean age = 56.11) in study 2 completed a diagnostic interview assessing lifetime presence of psychological disorders. They also rated their pain, fatigue, physical functioning, and self-rated health. Covariates included body mass index, age, cancer stage, menopause status, and physical comorbidities.
RESULTS RESULTS
Results from both studies indicated that a distress disorder history was associated with higher pain, fatigue, and sleep difficulties as well as lower self-rated health compared to those without such a history.
CONCLUSIONS CONCLUSIONS
These findings suggest that breast cancer survivors with a distress disorder may be particularly at risk for more physical symptoms, poorer sleep, and worse self-rated health both prior to and following adjuvant treatment.

Identifiants

pubmed: 35831698
doi: 10.1007/s12529-022-10115-4
pii: 10.1007/s12529-022-10115-4
pmc: PMC10278051
mid: NIHMS1904620
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

463-472

Subventions

Organisme : NCI NIH HHS
ID : R01 CA186720
Pays : United States
Organisme : NCATS NIH HHS
ID : TL1 TR002735
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA186251
Pays : United States
Organisme : NCI NIH HHS
ID : T32 CA229114
Pays : United States
Organisme : NCI NIH HHS
ID : R01CA186720
Pays : United States
Organisme : NCI NIH HHS
ID : R01CA186251
Pays : United States
Organisme : NIH HHS
ID : TL1TR002735
Pays : United States
Organisme : NIGMS NIH HHS
ID : U54 GM115428
Pays : United States
Organisme : NCI NIH HHS
ID : R01CA186720
Pays : United States
Organisme : NCI NIH HHS
ID : R01CA186251
Pays : United States
Organisme : NCI NIH HHS
ID : T32 CA229114
Pays : United States
Organisme : NIH HHS
ID : TL1TR002735
Pays : United States

Informations de copyright

© 2022. International Society of Behavioral Medicine.

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Auteurs

Megan E Renna (ME)

School of Psychology, University of Southern Mississippi, 118 College Drive #5025, Hattiesburg, MS, 39406, USA. megan.renna@usm.edu.

M Rosie Shrout (MR)

Purdue University, West Lafayette, USA.

Annelise A Madison (AA)

The Ohio State University, Columbus, USA.

Maryam Lustberg (M)

Yale School of Medicine, New Haven, USA.

Stephen P Povoski (SP)

The Ohio State University College of Medicine, Columbus, USA.

Doreen M Agnese (DM)

The Ohio State University College of Medicine, Columbus, USA.

Raquel E Reinbolt (RE)

The Ohio State University College of Medicine, Columbus, USA.

Robert Wesolowski (R)

The Ohio State University College of Medicine, Columbus, USA.

Nicole O Williams (NO)

The Ohio State University College of Medicine, Columbus, USA.

Bhuvaneswari Ramaswamy (B)

The Ohio State University College of Medicine, Columbus, USA.

Sagar D Sardesai (SD)

The Ohio State University College of Medicine, Columbus, USA.

Anne M Noonan (AM)

The Ohio State University College of Medicine, Columbus, USA.

Jeffrey B VanDeusen (JB)

The Ohio State University College of Medicine, Columbus, USA.

Daniel G Stover (DG)

The Ohio State University College of Medicine, Columbus, USA.

Mathew Cherian (M)

The Ohio State University College of Medicine, Columbus, USA.

William B Malarkey (WB)

The Ohio State University College of Medicine, Columbus, USA.

Michael Di Gregorio (M)

The Ohio State University College of Medicine, Columbus, USA.

Janice K Kiecolt-Glaser (JK)

The Ohio State University College of Medicine, Columbus, USA.

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