Low Stroke Risk in Children With Sickle Cell Disease in French Guiana: A Retrospective Cohort Study.

French Guiana children incidence sickle cell disease stroke

Journal

Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047

Informations de publication

Date de publication:
2022
Historique:
received: 10 01 2022
accepted: 27 05 2022
entrez: 15 7 2022
pubmed: 16 7 2022
medline: 16 7 2022
Statut: epublish

Résumé

One in every 227 babies born in French Guiana has sickle cell disease, which represents the greatest incidence in France. This study aimed to determine the incidence of stroke in children with sickle cell disease and its associated risk factors. This retrospective cohort study included all children with sickle cell disease diagnosed in the neonatal period who were born in French Guiana between 01/01/1992 and 12/31/2002. Of a total of 218 records, 122 patients were included. There were 70 HbSS/Sβ0 (58%), 40 HbSC (33%), and 11 Sβ + thalassemia (9%). The number of emergency admissions was significantly different between genotypes, with a higher number in SS/Sβ0 children (

Identifiants

pubmed: 35836958
doi: 10.3389/fmed.2022.851918
pmc: PMC9273747
doi:

Types de publication

Journal Article

Langues

eng

Pagination

851918

Informations de copyright

Copyright © 2022 Gargot, Parriault, Adenis, Clouzeau, Dinh Van, Ntab, Defo, Nacher and Elenga.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Julie Gargot (J)

Service de Pédiatrie, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana.

Marie-Claire Parriault (MC)

CIC INSERM 1424, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana.

Antoine Adenis (A)

CIC INSERM 1424, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana.

Jérôme Clouzeau (J)

Service de Pédiatrie, Centre Hospitalier de l'Ouest-Guyanais «Franck Joly», Saint-Laurent-du-Maroni, French Guiana.

Kim-Anh Dinh Van (KA)

Département d'Information Médical, Centre Hospitalier de Kourou, Kourou, French Guiana.

Balthazar Ntab (B)

Département d'Information Médicale, Centre Hospitalier de l'Ouest-Guyanais «Franck Joly», Saint-Laurent-du-Maroni, French Guiana.

Antoine Defo (A)

Service de Pédiatrie, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana.

Mathieu Nacher (M)

CIC INSERM 1424, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana.

Narcisse Elenga (N)

Service de Pédiatrie, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana.

Classifications MeSH