Infrapatellar Fat Pad-Synovial Membrane Anatomo-Fuctional Unit: Microscopic Basis for Piezo1/2 Mechanosensors Involvement in Osteoarthritis Pain.
Piezo1/2
anatomo-functional unit
biomechanics
infrapatellar fat pad
knee
osteoarthritis
pain
synovial membrane
Journal
Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250
Informations de publication
Date de publication:
2022
2022
Historique:
received:
28
02
2022
accepted:
09
06
2022
entrez:
15
7
2022
pubmed:
16
7
2022
medline:
16
7
2022
Statut:
epublish
Résumé
The Infrapatellar Fat Pad (IFP) is a fibro-adipose tissue of the knee recently reconsidered as part of a single anatomo-functional unit (AFU) together with the synovial membrane (SM). Several evidence support the role of this unit in the mechanisms that trigger and perpetuate the onset and progression of osteoarthritis (OA) disease. Additionally, the contribution of IFP-SM AFU in OA-associated pain has also been supposed, but this assumption still needs to be fully elucidated. Within this context, the recent discovery of the mechanoceptive Piezo ion channels (i.e., Piezo1 and Piezo2) in mammals and consciousness on their role in mediating both mechanoceptive and inflammatory stimuli could shed some light on knee OA pain, as well as on the process leading from acute to chronic nociceptive responses. For this purpose, the IFP-SM AFUs of both healthy donors (non-OA IFP-SM AFUs,
Identifiants
pubmed: 35837327
doi: 10.3389/fcell.2022.886604
pii: 886604
pmc: PMC9274201
doi:
Types de publication
Journal Article
Langues
eng
Pagination
886604Informations de copyright
Copyright © 2022 Emmi, Stocco, Boscolo-Berto, Contran, Belluzzi, Favero, Ramonda, Porzionato, Ruggieri, De Caro and Macchi.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
J Biomech Eng. 2013 Feb;135(2):021003
pubmed: 23445048
Bone. 2012 Aug;51(2):249-57
pubmed: 22387238
Osteoarthritis Cartilage. 2020 Mar;28(3):267-274
pubmed: 31877382
Clin Exp Rheumatol. 2019 Sep-Oct;37 Suppl 120(5):57-63
pubmed: 31621560
Arthritis Rheumatol. 2019 Jul;71(7):1078-1088
pubmed: 30638309
J Neurosci. 2013 Feb 13;33(7):2849-59
pubmed: 23407944
Osteoarthritis Cartilage. 2020 May;28(5):555-561
pubmed: 31982565
Br J Sports Med. 2005 Jul;39(7):458-61; discussion 458-61
pubmed: 15976171
Osteoarthritis Cartilage. 2013 Sep;21(9):1145-53
pubmed: 23973124
Curr Osteoporos Rep. 2018 Oct;16(5):611-616
pubmed: 30155845
Australas Phys Eng Sci Med. 2018 Sep;41(3):657-667
pubmed: 29943312
Front Cell Dev Biol. 2022 Mar 25;10:889210
pubmed: 35399513
Osteoarthritis Cartilage. 2020 May;28(5):562-571
pubmed: 31862470
Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):E5114-22
pubmed: 25385580
Tohoku J Exp Med. 2010 Jun;221(2):161-8
pubmed: 20501969
Mol Pain. 2015 Oct 24;11:65
pubmed: 26497944
J Cell Physiol. 2017 Aug;232(8):1971-1978
pubmed: 27925193
Front Neuroanat. 2021 Apr 16;15:663399
pubmed: 33935659
Jpn J Vet Res. 2001 Aug;49(2):115-23
pubmed: 11590919
Osteoarthritis Cartilage. 2022 Mar;30(3):406-415
pubmed: 34861384
Clin Anat. 2020 Sep;33(6):950-959
pubmed: 32427400
J Mol Cell Cardiol. 2021 Jul;156:20-32
pubmed: 33753119
Osteoarthritis Cartilage. 2011 May;19(5):478-82
pubmed: 21396464
Arthritis Res Ther. 2016 Jul 16;18:170
pubmed: 27424032
Best Pract Res Clin Rheumatol. 2011 Dec;25(6):815-23
pubmed: 22265263
Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10347-52
pubmed: 24958852
Maturitas. 2016 Jul;89:22-8
pubmed: 27180156
Curr Rheumatol Rep. 2018 Feb 26;20(2):9
pubmed: 29480410
Expert Rev Mol Med. 2021 Oct 27;23:e14
pubmed: 34702419
Front Cell Dev Biol. 2019 Dec 10;7:323
pubmed: 31921840
Pain Med. 2021 May 21;22(5):1229-1232
pubmed: 32914191
Rheumatology (Oxford). 2011 Feb;50(2):245-7
pubmed: 21242247
J Forensic Sci. 2020 Nov;65(6):2155-2159
pubmed: 32957166
Pain Med. 2015 Jul;16(7):1373-85
pubmed: 26176791
Wound Repair Regen. 2021 Jul;29(4):642-649
pubmed: 34021514
BMJ. 2021 Jan 20;372:m4825
pubmed: 33472813
Cells Tissues Organs. 2016;201(3):220-31
pubmed: 26796341
J Rheumatol. 2016 Apr;43(4):771-8
pubmed: 26980579
Br J Pharmacol. 2018 Apr;175(8):1354-1361
pubmed: 28369744
Anat Sci Educ. 2011 May-Jun;4(3):151-6
pubmed: 21491611
BMC Musculoskelet Disord. 2010 May 06;11:86
pubmed: 20459622
Stem Cell Res Ther. 2019 Aug 19;10(1):260
pubmed: 31426847
Front Med (Lausanne). 2021 May 10;8:661403
pubmed: 34041253
Biochem Pharmacol. 2019 Jul;165:66-78
pubmed: 30936016
J Biomech. 2022 Jan;131:110931
pubmed: 34972018
J Orthop Translat. 2020 Sep 28;26:3-15
pubmed: 33437618
Aging (Albany NY). 2022 Jan 4;14(1):286-296
pubmed: 34983026
Arthritis Res Ther. 2006;8(6):R165
pubmed: 17076892
Anat Sci Educ. 2012 Sep-Oct;5(5):264-72
pubmed: 22573575
Connect Tissue Res. 2019 Mar;60(2):136-145
pubmed: 29695173
Osteoarthritis Cartilage. 2019 Mar;27(3):392-400
pubmed: 30597275
Cell Death Dis. 2021 Mar 1;12(3):226
pubmed: 33649312
Eklem Hastalik Cerrahisi. 2010 Apr;21(1):2-14
pubmed: 20302555
Rheumatology (Oxford). 2017 Oct 1;56(10):1784-1793
pubmed: 28957567
Arch Pharm Res. 2021 Jan;44(1):1-15
pubmed: 33230600
Int J Mol Sci. 2020 Aug 21;21(17):
pubmed: 32825633
Curr Top Membr. 2017;79:245-261
pubmed: 28728819
Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):
pubmed: 33758095
Int J Mol Sci. 2018 Dec 18;19(12):
pubmed: 30567407
Biomed Res Int. 2019 Mar 31;2019:6390182
pubmed: 31049352
Front Pharmacol. 2021 Apr 15;12:668714
pubmed: 33935792
Curr Rheumatol Rep. 2016 Jul;18(7):40
pubmed: 27177901
J Pain. 2014 Jul;15(7):771-7
pubmed: 24793242
J Knee Surg. 2021 Mar;34(4):415-421
pubmed: 31505700
J Pain Res. 2020 Jul 08;13:1699-1711
pubmed: 32753945
Cytokine Growth Factor Rev. 2018 Dec;44:38-50
pubmed: 30340925
J Orthop Surg (Hong Kong). 2020 Sep-Dec;28(3):2309499020950262
pubmed: 32840428
J Tissue Eng. 2022 Jan 25;13:20417314211065860
pubmed: 35096363
Nat Rev Rheumatol. 2012 May 29;8(7):390-8
pubmed: 22641138
J Histochem Cytochem. 1999 Mar;47(3):343-52
pubmed: 10026236
Osteoarthritis Cartilage. 2020 May;28(5):544-554
pubmed: 31926267
Proc Natl Acad Sci U S A. 2020 May 5;117(18):9896-9905
pubmed: 32321834
Nat Rev Rheumatol. 2019 Jun;15(6):355-363
pubmed: 31068673
Am J Transl Res. 2020 Jan 15;12(1):261-268
pubmed: 32051751
J Cell Physiol. 2021 Apr;236(4):2976-2987
pubmed: 32959903
Nat Rev Rheumatol. 2010 Nov;6(11):625-35
pubmed: 20924410
Arthritis Rheum. 2012 Jun;64(6):1697-707
pubmed: 22392533
Rheumatology (Oxford). 2015 Nov;54(11):1954-63
pubmed: 26175472
Arthritis Res Ther. 2009;11(3):227
pubmed: 19519925
Curr Top Membr. 2017;79:263-273
pubmed: 28728820
Nat Rev Dis Primers. 2016 Oct 13;2:16072
pubmed: 27734845
Front Immunol. 2011 Oct 10;2:52
pubmed: 22566842
J Anat. 2018 Aug;233(2):146-154
pubmed: 29761471