Antimicrobial Resistance Rates and Surveillance in Sub-Saharan Africa: Where Are We Now?
GAP
NAP
antimicrobial resistance
sub-Saharan Africa
surveillance
Journal
Infection and drug resistance
ISSN: 1178-6973
Titre abrégé: Infect Drug Resist
Pays: New Zealand
ID NLM: 101550216
Informations de publication
Date de publication:
2022
2022
Historique:
received:
15
03
2022
accepted:
16
06
2022
entrez:
15
7
2022
pubmed:
16
7
2022
medline:
16
7
2022
Statut:
epublish
Résumé
Although antimicrobials have traditionally been used to treat infections and improve health outcomes, resistance to commonly used antimicrobials has posed a major challenge. An estimated 700,000 deaths occur globally every year as a result of infections caused by antimicrobial-resistant pathogens. Antimicrobial resistance (AMR) also contributes directly to the decline in the global economy. In 2019, sub-Saharan Africa (SSA) had the highest mortality rate (23.5 deaths per 100,000) attributable to AMR compared to other regions. We searched PubMed for articles relevant to AMR in pathogens in the WHO-GLASS list and in other infections of local importance in SSA. In this review, we focused on AMR rates and surveillance of AMR for these priority pathogens and some of the most encountered pathogens of public health significance. In addition, we reviewed the implementation of national action plans to mitigate against AMR in countries in SSA. The SSA region is disproportionately affected by AMR, in part owing to the prevailing high levels of poverty, which result in a high burden of infectious diseases, poor regulation of antimicrobial use, and a lack of alternatives to ineffective antimicrobials. The global action plan as a strategy for prevention and combating AMR has been adopted by most countries, but fewer countries are able to fully implement country-specific action plans, and several challenges exist in many settings. A concerted One Health approach will be required to ramp up implementation of action plans in the region. In addition to AMR surveillance, effective implementation of infection prevention and control, water, sanitation, and hygiene, and antimicrobial stewardship programs will be key cost-effective strategies in helping to tackle AMR.
Identifiants
pubmed: 35837538
doi: 10.2147/IDR.S342753
pii: 342753
pmc: PMC9273632
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
3589-3609Subventions
Organisme : NIAID NIH HHS
ID : R01 AI099525
Pays : United States
Informations de copyright
© 2022 Kariuki et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in relation to this work.
Références
Antibiotics (Basel). 2020 Apr 23;9(4):
pubmed: 32340386
PLoS One. 2015 Sep 08;10(9):e0137531
pubmed: 26348037
Lancet Infect Dis. 2018 Nov;18(11):1211-1228
pubmed: 30243583
Nat Rev Microbiol. 2022 May;20(5):257-269
pubmed: 34737424
Clin Infect Dis. 2015 Nov 1;61 Suppl 4:S339-45
pubmed: 26449950
Front Microbiol. 2021 Dec 01;12:770130
pubmed: 34925277
Sci Rep. 2021 Apr 1;11(1):7359
pubmed: 33795754
Emerg Microbes Infect. 2021 Dec;10(1):865-873
pubmed: 33879019
Emerg Infect Dis. 2010 May;16(5):879-80
pubmed: 20409393
Clin Infect Dis. 2019 Oct 30;69(Suppl 6):S466-S473
pubmed: 31665773
Clin Vaccine Immunol. 2017 Jul 5;24(7):
pubmed: 28515136
Trop Med Int Health. 2021 Aug;26(8):862-881
pubmed: 33942448
Clin Infect Dis. 2020 Jul 29;71(Suppl 2):S127-S129
pubmed: 32725224
Vaccines (Basel). 2021 Jun 01;9(6):
pubmed: 34205838
Biomed Res Int. 2020 Sep 24;2020:3852419
pubmed: 33029505
PLoS Negl Trop Dis. 2014 Mar 06;8(3):e2726
pubmed: 24603860
Arch Dis Child. 2020 Jan;105(1):26-31
pubmed: 31446393
Crit Rev Food Sci Nutr. 2017 Sep 2;57(13):2857-2876
pubmed: 26464037
Molecules. 2018 Mar 30;23(4):
pubmed: 29601469
J Water Health. 2020 Dec;18(6):858-866
pubmed: 33328358
Front Microbiol. 2022 Mar 14;13:835403
pubmed: 35369511
Front Med (Lausanne). 2022 Mar 07;9:846051
pubmed: 35321470
Front Microbiol. 2017 May 15;8:748
pubmed: 28555129
Clin Infect Dis. 2014 Mar;58(5):638-47
pubmed: 24336909
Clin Infect Dis. 2019 Nov 13;69(Suppl 7):S521-S528
pubmed: 31724045
Front Microbiol. 2019 Jul 25;10:1689
pubmed: 31404242
S Afr Med J. 2015 Apr 06;105(5):325
pubmed: 26242647
PLoS One. 2018 Dec 21;13(12):e0209623
pubmed: 30576382
EcoSal Plus. 2019 Jan;8(2):
pubmed: 30657108
BMC Infect Dis. 2019 Oct 16;19(1):853
pubmed: 31619192
Genome Res. 2009 Dec;19(12):2279-87
pubmed: 19901036
Int J Environ Res Public Health. 2019 May 05;16(9):
pubmed: 31060262
Vaccine. 2015 Jun 19;33 Suppl 3:C8-15
pubmed: 25937611
Gastroenterol Hepatol Bed Bench. 2020 Summer;13(3):238-246
pubmed: 32821354
PLoS One. 2014 Feb 25;9(2):e89716
pubmed: 24586981
Emerg Infect Dis. 2019 Apr;25(4):739-747
pubmed: 30882333
Lancet. 2022 Feb 12;399(10325):629-655
pubmed: 35065702
PLoS One. 2017 Nov 16;12(11):e0188216
pubmed: 29145465
PLoS One. 2020 Jul 10;15(7):e0236016
pubmed: 32649692
Clin Microbiol Rev. 2008 Jul;21(3):538-82
pubmed: 18625687
Antimicrob Resist Infect Control. 2020 Aug 28;9(1):145
pubmed: 32859252
Clin Microbiol Infect. 2014 Jul;20(7):589-96
pubmed: 24861767
Int J Infect Dis. 2020 Jul;96:621-629
pubmed: 32505875
PLoS One. 2015 Nov 25;10(11):e0142989
pubmed: 26606536
Antimicrob Resist Infect Control. 2020 Nov 26;9(1):187
pubmed: 33243302
PLoS Negl Trop Dis. 2019 Jun 20;13(6):e0007485
pubmed: 31220112
PLoS One. 2021 Apr 29;16(4):e0250896
pubmed: 33914829
Antimicrob Resist Infect Control. 2018 Jul 4;7:79
pubmed: 29997889
Pediatr Infect Dis J. 2010 Jun;29(6):504-10
pubmed: 20104200
J Clin Microbiol. 2010 Jun;48(6):2171-6
pubmed: 20392916
J Glob Antimicrob Resist. 2020 Mar;20:170-177
pubmed: 31401170
BMC Res Notes. 2018 Apr 3;11(1):226
pubmed: 29615129
Antimicrob Resist Infect Control. 2018 Jan 5;7:2
pubmed: 29312659
Microbiology (Reading). 2021 May;167(5):
pubmed: 34032566
PLoS Negl Trop Dis. 2020 Aug 3;14(8):e0008440
pubmed: 32745137
Int J Antimicrob Agents. 2021 Oct;58(4):106411
pubmed: 34371112
BMC Infect Dis. 2019 May 31;19(1):487
pubmed: 31151421
Antimicrob Agents Chemother. 2015;59(6):3133-9
pubmed: 25779570
PLoS One. 2017 Aug 8;12(8):e0181496
pubmed: 28792540
Afr J Infect Dis. 2017 Jun 08;11(2):68-74
pubmed: 28670642
Antibiotics (Basel). 2021 Jun 23;10(7):
pubmed: 34201723
PLoS Negl Trop Dis. 2013;7(2):e2049
pubmed: 23459673
Infect Drug Resist. 2020 Dec 22;13:4615-4626
pubmed: 33376367
PLoS Negl Trop Dis. 2017 Jan 5;11(1):e0005118
pubmed: 28056035
Saudi J Biol Sci. 2017 May;24(4):808-812
pubmed: 28490950
Patient Prefer Adherence. 2020 Aug 19;14:1445-1453
pubmed: 32884246
Clin Infect Dis. 2015 Nov 1;61 Suppl 4:S235-40
pubmed: 26449937
Springerplus. 2016 Aug 09;5(1):1308
pubmed: 27547682
PLoS Negl Trop Dis. 2020 Apr 2;14(4):e0008121
pubmed: 32240161
Lancet. 2018 May 12;391(10133):1908-1915
pubmed: 29502905
PLoS One. 2017 Jul 18;12(7):e0181145
pubmed: 28719665
Lancet Infect Dis. 2019 Nov;19(11):1219-1234
pubmed: 31522858
Expert Rev Anti Infect Ther. 2011 Jun;9(6):711-25
pubmed: 21692675
Curr Microbiol. 2021 Dec 14;79(1):27
pubmed: 34905085
Nat Microbiol. 2021 Mar;6(3):327-338
pubmed: 33349664
Emerg Infect Dis. 2015 Apr;21(4):655-9
pubmed: 25811307
Clin Infect Dis. 2016 Mar 15;62 Suppl 1:S23-31
pubmed: 26933016
PLoS One. 2019 Sep 12;14(9):e0222168
pubmed: 31513633
Global Health. 2020 Nov 11;16(1):109
pubmed: 33176810
Front Cell Infect Microbiol. 2021 Nov 25;11:771510
pubmed: 34900756
J Infect. 2021 Nov;83(5):523-532
pubmed: 34260964
Emerg Microbes Infect. 2019;8(1):1747-1759
pubmed: 31805829
Int J Infect Dis. 2016 May;46:38-41
pubmed: 27021530
BMC Public Health. 2019 Jun 10;19(1):726
pubmed: 31182071
Crit Care Nurse. 2008 Feb;28(1):15-25; quiz 26
pubmed: 18238934
BMC Infect Dis. 2021 Jan 7;21(1):30
pubmed: 33413186
Front Public Health. 2019 Nov 27;7:348
pubmed: 31828054
Bull World Health Organ. 2010 Jun;88(6):402
pubmed: 20539847
PLoS Negl Trop Dis. 2012;6(11):e1921
pubmed: 23166855
PLoS One. 2016 Aug 01;11(8):e0159794
pubmed: 27479360
J Infect Dis. 2016 Jul 1;214(1):6-15
pubmed: 26931446
Int J Gen Med. 2019 Nov 06;12:395-403
pubmed: 31819592
PLoS One. 2014 Sep 04;9(9):e107008
pubmed: 25187957
Antibiotics (Basel). 2021 Aug 13;10(8):
pubmed: 34439026
BMC Infect Dis. 2016 Jun 10;16:271
pubmed: 27286886
J Biotechnol. 2016 Sep 10;233:190-9
pubmed: 27411901
BMC Res Notes. 2018 Jan 18;11(1):45
pubmed: 29347965
Int J Med Microbiol. 2017 Oct;307(7):422-429
pubmed: 28789913
Microbiol Spectr. 2018 Mar;6(2):
pubmed: 29600770
Pathogens. 2021 Mar 19;10(3):
pubmed: 33808905
Environ Sci Technol. 2015 Oct 20;49(20):11993-2004
pubmed: 26355462
Niger J Clin Pract. 2018 Feb;21(2):176-182
pubmed: 29465051
J Glob Infect Dis. 2019 Jan-Mar;11(1):36-42
pubmed: 30814834
PLoS One. 2021 Feb 22;16(2):e0246937
pubmed: 33617559
Clin Infect Dis. 2015 Nov 1;61 Suppl 4:S332-8
pubmed: 26449949
Nat Commun. 2018 Nov 30;9(1):5094
pubmed: 30504848
Front Microbiol. 2019 Mar 22;10:593
pubmed: 30967856
J Infect. 2008 Jun;56(6):413-22
pubmed: 18474400
Antimicrob Agents Chemother. 2016 Apr 22;60(5):3240-2
pubmed: 26883710
J Travel Med. 2019 Dec 23;26(8):
pubmed: 31115466
Int J Infect Dis. 2018 Aug;73:78-84
pubmed: 29908251
J Glob Antimicrob Resist. 2019 Jun;17:132-136
pubmed: 30557686
BMC Genomics. 2019 Mar 25;20(1):241
pubmed: 30909880
Environ Health Prev Med. 2021 Oct 5;26(1):100
pubmed: 34610785
J Med Microbiol. 2006 May;55(Pt 5):585-591
pubmed: 16585646
Lancet Infect Dis. 2019 Apr;19(4):369-381
pubmed: 30792131
BMC Public Health. 2019 Oct 29;19(1):1405
pubmed: 31664972
Clin Infect Dis. 2019 Feb 15;68(Suppl 1):S10-S15
pubmed: 30767004
J Glob Antimicrob Resist. 2020 Sep;22:145-146
pubmed: 32522550
BMC Res Notes. 2019 Jul 16;12(1):422
pubmed: 31311578
Antimicrob Resist Infect Control. 2017 May 15;6:47
pubmed: 28515903
Lancet Planet Health. 2018 Sep;2(9):e398-e405
pubmed: 30177008
Lancet Infect Dis. 2018 Mar;18(3):318-327
pubmed: 29276051
Expert Rev Anti Infect Ther. 2015 May;13(5):567-73
pubmed: 25850806
J Hosp Med. 2018 Jan 25;13(5):361.362
pubmed: 29370317
Biomed Res Int. 2020 Nov 19;2020:4250165
pubmed: 33294442
Front Microbiol. 2016 Sep 07;7:1420
pubmed: 27656179
Clin Infect Dis. 2015 Nov 1;61 Suppl 4:S325-31
pubmed: 26449948
Lancet Infect Dis. 2019 Jan;19(1):56-66
pubmed: 30409683
Front Microbiol. 2017 May 04;8:730
pubmed: 28522992
Infect Drug Resist. 2018 Oct 11;11:1757-1765
pubmed: 30349333
Antibiotics (Basel). 2020 Aug 09;9(8):
pubmed: 32784880
BMJ Open. 2020 Dec 17;10(12):e037997
pubmed: 33334828
Clin Infect Dis. 2019 Oct 30;69(Suppl 6):S417-S421
pubmed: 31665772
Front Microbiol. 2020 Nov 13;11:587398
pubmed: 33281784
Clin Microbiol Infect. 2016 May;22(5):416-22
pubmed: 26706614
Nat Genet. 2015 Jun;47(6):632-9
pubmed: 25961941
Microb Genom. 2021 Nov;7(11):
pubmed: 34812716
PLoS One. 2012;7(12):e51981
pubmed: 23284838
Lancet Planet Health. 2021 Dec;5(12):e893-e904
pubmed: 34774223
BMC Infect Dis. 2014 Mar 04;14:124
pubmed: 24592922
Lancet Infect Dis. 2019 Dec;19(12):1312-1324
pubmed: 31562022
Science. 2019 Sep 20;365(6459):
pubmed: 31604207
BMC Infect Dis. 2020 Oct 7;20(1):729
pubmed: 33028225
Sci Rep. 2019 Apr 18;9(1):6266
pubmed: 31000772
Infect Genet Evol. 2011 Dec;11(8):1951-6
pubmed: 21896336
Clin Infect Dis. 2019 Mar 7;68(Suppl 2):S130-S137
pubmed: 30845337
Sci Rep. 2020 Jan 27;10(1):1232
pubmed: 31988374
PLoS One. 2015 Dec 31;10(12):e0145429
pubmed: 26719975
BMC Res Notes. 2017 Jul 14;10(1):284
pubmed: 28705201
Elife. 2021 Sep 13;10:
pubmed: 34515028
PLoS Negl Trop Dis. 2015 Apr 24;9(4):e0003748
pubmed: 25909750
Afr J Lab Med. 2018 Dec 06;7(2):830
pubmed: 30568906
J Clin Microbiol. 2015 Jan;53(1):262-72
pubmed: 25392358
Clin Infect Dis. 2015 Nov 1;61 Suppl 4:S363-71
pubmed: 26449953
BMC Infect Dis. 2021 Jan 7;21(1):34
pubmed: 33413184
Nat Commun. 2016 Oct 05;7:12827
pubmed: 27703135
Nat Rev Microbiol. 2020 Jun;18(6):344-359
pubmed: 32055025
Afr J Prim Health Care Fam Med. 2020 Dec 08;12(1):e1-e6
pubmed: 33354982
Infect Dis (Lond). 2020 Sep;52(9):644-650
pubmed: 32516021
PLoS One. 2012;7(2):e31237
pubmed: 22363591
BMJ Glob Health. 2021 Aug;6(8):
pubmed: 34341020
Virulence. 2012 May 1;3(3):243-50
pubmed: 22546906
Braz J Microbiol. 2022 Mar;53(1):465-486
pubmed: 34775576
J Antimicrob Chemother. 2021 Apr 13;76(5):1160-1167
pubmed: 33347558
BMC Res Notes. 2018 Aug 31;11(1):629
pubmed: 30170613
BMC Infect Dis. 2019 Jul 9;19(1):596
pubmed: 31288757
BMC Infect Dis. 2006 Nov 07;6:160
pubmed: 17090299
Clin Infect Dis. 2015 Nov 1;61 Suppl 4:S302-9
pubmed: 26449945
Lancet Microbe. 2022 Jan;3(1):e2-e3
pubmed: 35544113
Microb Genom. 2021 Nov;7(11):
pubmed: 34793293
Front Microbiol. 2018 Jun 12;9:1280
pubmed: 29946315
BMC Res Notes. 2011 Sep 07;4:326
pubmed: 21899769
Front Microbiol. 2021 Feb 18;12:614058
pubmed: 33679638
Infect Drug Resist. 2019 Dec 20;12:3903-3910
pubmed: 31908502
Am J Trop Med Hyg. 2018 Sep;99(3_Suppl):41-47
pubmed: 30047362
PLoS One. 2020 Mar 12;15(3):e0230031
pubmed: 32163464