Diagnosis and Prevention of Hypersensitivity Reactions to Iodinated Contrast Media.
Contrast media
drug allergy
hypersensitivity
skin tests
Journal
Allergy, asthma & immunology research
ISSN: 2092-7355
Titre abrégé: Allergy Asthma Immunol Res
Pays: Korea (South)
ID NLM: 101518382
Informations de publication
Date de publication:
Jul 2022
Jul 2022
Historique:
received:
18
05
2022
revised:
21
06
2022
accepted:
29
06
2022
entrez:
15
7
2022
pubmed:
16
7
2022
medline:
16
7
2022
Statut:
ppublish
Résumé
Iodinated contrast media (ICM) have become one of the major causes of drug hypersensitivity reactions (HSRs) related to increasing numbers of ICM-based radiological imaging procedures. Strategies for diagnosing and preventing ICM-induced HSRs have not been uniformly standardized yet. However, advances have been made based on the results of recent research. A previous history of hypersensitivity to ICM is the most significant risk factor for developing HSR by ICM. Avoidance of culprit agents and premedication is the main strategy to prevent recurrences of HSRs in high-risk patients. In addition, we strongly recommend identifying sensitized ICM using skin tests to determine immunoglobulin E-mediated or delayed-type allergy and to guide the choice of an alternative contrast agent. ICM provocation test procedures have been established and are helpful in selected cases. In this paper, we review how to evaluate patients who have experienced immediate or delayed HSRs caused by ICM to minimize the risk of recurrence and discuss unmet needs that require further research.
Identifiants
pubmed: 35837820
pii: 14.348
doi: 10.4168/aair.2022.14.4.348
pmc: PMC9293596
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
348-360Informations de copyright
Copyright © 2022 The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease.
Déclaration de conflit d'intérêts
There are no financial or other issues that might lead to a conflict of interest.
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