Intraocular Water Movement Visualization Using
MRI contrast agent
aqueous humor
in vivo human eye
oxygen-17 water
Journal
Journal of magnetic resonance imaging : JMRI
ISSN: 1522-2586
Titre abrégé: J Magn Reson Imaging
Pays: United States
ID NLM: 9105850
Informations de publication
Date de publication:
03 2023
03 2023
Historique:
revised:
21
06
2022
received:
14
04
2022
accepted:
22
06
2022
pubmed:
16
7
2022
medline:
22
2
2023
entrez:
15
7
2022
Statut:
ppublish
Résumé
Visualization of aqueous humor flow in MR contrast images using gadolinium is challenging because of the delayed contrast effects associated with the blood-retinal and blood-aqueous humor barriers. However, oxygen-17 water (H To observe the distribution of H Prospective. Six ophthalmologically normal volunteers (20-37 years, six females). A 3 T/dynamic T2-weighted MRI. H A paired t-test was used to compare the flow-related values and temporal changes in signal intensity. P-values < 0.05 were considered statistically significant. Significantly decreased signal intensity was observed in the right anterior chamber but not the right vitreous body (P = 0.39). The nAC signal intensity decreased significantly and then recovered. The inflow and outflow constants were 0.36-0.94 min H 2 TECHNICAL EFFICACY STAGE: 2.
Sections du résumé
BACKGROUND
Visualization of aqueous humor flow in MR contrast images using gadolinium is challenging because of the delayed contrast effects associated with the blood-retinal and blood-aqueous humor barriers. However, oxygen-17 water (H
PURPOSE
To observe the distribution of H
STUDY TYPE
Prospective.
POPULATION
Six ophthalmologically normal volunteers (20-37 years, six females).
FIELD STRENGTH/SEQUENCE
A 3 T/dynamic T2-weighted MRI.
ASSESSMENT
H
STATISTICAL TESTS
A paired t-test was used to compare the flow-related values and temporal changes in signal intensity. P-values < 0.05 were considered statistically significant.
RESULTS
Significantly decreased signal intensity was observed in the right anterior chamber but not the right vitreous body (P = 0.39). The nAC signal intensity decreased significantly and then recovered. The inflow and outflow constants were 0.36-0.94 min
DATA CONCLUSION
H
LEVEL OF EVIDENCE
2 TECHNICAL EFFICACY STAGE: 2.
Substances chimiques
Ophthalmic Solutions
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
845-853Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2022 The Authors. Journal of Magnetic Resonance Imaging published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.
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