Rapid repeat infection of SARS-CoV-2 by two highly distinct delta-lineage viruses.
SARS-CoV-2
delta
mutations
reinfection
Journal
Diagnostic microbiology and infectious disease
ISSN: 1879-0070
Titre abrégé: Diagn Microbiol Infect Dis
Pays: United States
ID NLM: 8305899
Informations de publication
Date de publication:
Sep 2022
Sep 2022
Historique:
received:
09
11
2021
revised:
01
06
2022
accepted:
15
06
2022
pubmed:
18
7
2022
medline:
3
8
2022
entrez:
17
7
2022
Statut:
ppublish
Résumé
An instance of sequential infection of an individual with, firstly, the Delta variant and secondly a Delta-sub-lineage has been identified. The individual was found positive for the AY.26 lineage 22 days after being found positive for the Delta [B.1.617.2] variant. The viruses associated with the cases showed dramatic genomic difference, including 31 changes that resulted in deletions or amino acid substitutions. Seven of these differences were observed in the Spike protein. The patient in question was between 30 and 35 years old and had no underlying health conditions. Though singular, this case illustrates the possibility that infection with the Delta variant may not itself be fully protective against a population of SARS-CoV-2 variants that are becoming increasingly diverse.
Identifiants
pubmed: 35843112
pii: S0732-8893(22)00113-4
doi: 10.1016/j.diagmicrobio.2022.115747
pmc: PMC9217632
pii:
doi:
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
115747Informations de copyright
Copyright © 2022 The Author(s). Published by Elsevier Inc. All rights reserved.
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