Changes in oral function, swallowing function, and quality of life in patients with head and neck cancer: a prospective cohort study.

Deglutition Deglutition Disorders / etiology Head and Neck Neoplasms / complications Humans Prospective Studies Quality of Life Surveys and Questionnaires
Dysphagia Head and neck cancer Morbidity Oral function Quality of life Swallowing

Journal

BMC oral health
ISSN: 1472-6831
Titre abrégé: BMC Oral Health
Pays: England
ID NLM: 101088684

Informations de publication

Date de publication:
17 07 2022
Historique:
received: 26 01 2022
accepted: 12 07 2022
entrez: 17 7 2022
pubmed: 18 7 2022
medline: 20 7 2022
Statut: epublish

Résumé

Head and neck cancer (HNC) treatment can cause oral morbidities, such as oral dryness and dysphagia, affecting the patient's quality of life (QOL). The relationship between oral functions and QOL in patients with early-stage HNC remains poorly studied. This study aimed to evaluate changes in the QOL of patients with early-stage HNC and identify factors that affect the QOL of these patients. In this prospective cohort study, 37 patients who underwent early-stage (Stage I/Stage II) HNC treatment were evaluated for their oral function, swallowing function, and the QOL score at baseline (BL) and 12 months after surgical treatment (12 M). The participants were divided into two groups: patients who returned to the BL QOL score at 12 M (RE; n = 26) and those who did not (NR; n = 11). In total, 29.7% (11/37) patients with early-stage HNC did not return to the BL QOL score at 12 M. There was no significant difference between the RE and NR groups regarding the oral and swallowing function. Moreover, oral and swallowing function of all patients returned to the BL at 12 M. The NR group showed lower QOL scores than the RE group in the global health status, and "sticky saliva" parameters in the questionnaires. Restoration of the oral function is insufficient to improve the QOL of patients with early-stage HNC. The treatment of these patients should instead consider several factors that affect their QOL.

Sections du résumé

BACKGROUND
Head and neck cancer (HNC) treatment can cause oral morbidities, such as oral dryness and dysphagia, affecting the patient's quality of life (QOL). The relationship between oral functions and QOL in patients with early-stage HNC remains poorly studied. This study aimed to evaluate changes in the QOL of patients with early-stage HNC and identify factors that affect the QOL of these patients.
METHODS
In this prospective cohort study, 37 patients who underwent early-stage (Stage I/Stage II) HNC treatment were evaluated for their oral function, swallowing function, and the QOL score at baseline (BL) and 12 months after surgical treatment (12 M). The participants were divided into two groups: patients who returned to the BL QOL score at 12 M (RE; n = 26) and those who did not (NR; n = 11).
RESULTS
In total, 29.7% (11/37) patients with early-stage HNC did not return to the BL QOL score at 12 M. There was no significant difference between the RE and NR groups regarding the oral and swallowing function. Moreover, oral and swallowing function of all patients returned to the BL at 12 M. The NR group showed lower QOL scores than the RE group in the global health status, and "sticky saliva" parameters in the questionnaires.
CONCLUSION
Restoration of the oral function is insufficient to improve the QOL of patients with early-stage HNC. The treatment of these patients should instead consider several factors that affect their QOL.

Identifiants

DOI: 10.1186/s12903-022-02329-5 PMID: 35843950 PMC: PMC9288711
pubmed: 35843950
doi: 10.1186/s12903-022-02329-5
pii: 10.1186/s12903-022-02329-5
pmc: PMC9288711
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

293

Informations de copyright

© 2022. The Author(s).

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Auteurs

Yoshiaki Ihara (Y)

Division of Oral Functional Rehabilitation Medicine, Department of Special Needs Dentistry, School of Dentistry, Showa University, Kitasenzoku 2-1-1, Oh-taku, Tokyo, 145-8515, Japan. ikkun@dent.showa-u.ac.jp.
ORCID: 0000-0002-4324-2670

Hirotaka Kato (H)

Division of Oral Functional Rehabilitation Medicine, Department of Special Needs Dentistry, School of Dentistry, Showa University, Kitasenzoku 2-1-1, Oh-taku, Tokyo, 145-8515, Japan.

Yuichi Tashimo (Y)

Division of Oral Functional Rehabilitation Medicine, Department of Special Needs Dentistry, School of Dentistry, Showa University, Kitasenzoku 2-1-1, Oh-taku, Tokyo, 145-8515, Japan.
Head and Neck Oncology Center, Showa University Hospital, Tokyo, Japan.

Yoshiki Iizumi (Y)

Division of Oral Functional Rehabilitation Medicine, Department of Special Needs Dentistry, School of Dentistry, Showa University, Kitasenzoku 2-1-1, Oh-taku, Tokyo, 145-8515, Japan.

Yuma Fukunishi (Y)

Division of Oral Functional Rehabilitation Medicine, Department of Special Needs Dentistry, School of Dentistry, Showa University, Kitasenzoku 2-1-1, Oh-taku, Tokyo, 145-8515, Japan.

Hitoshi Sato (H)

Head and Neck Oncology Center, Showa University Hospital, Tokyo, Japan.

Toshikazu Shimane (T)

Head and Neck Oncology Center, Showa University Hospital, Tokyo, Japan.

Koji Takahashi (K)

Division of Oral Functional Rehabilitation Medicine, Department of Special Needs Dentistry, School of Dentistry, Showa University, Kitasenzoku 2-1-1, Oh-taku, Tokyo, 145-8515, Japan.

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Classifications MeSH

questionsmedicales.fr › Phénomènes physiologiques de l'appareil buccodentaire et de l'appareil digestif › Phénomènes physiologiques de l'appareil digestif › Déglutition › Changes in oral function, swallowing function,...
questionsmedicales.fr › Maladies oto-rhino-laryngologiques › Maladies du pharynx › Troubles de la déglutition › Changes in oral function, swallowing function,...
questionsmedicales.fr › Tumeurs › Tumeurs par siège › Tumeurs de la tête et du cou › Changes in oral function, swallowing function,...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Changes in oral function, swallowing function,...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études prospectives › Changes in oral function, swallowing function,...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Mesures épidémiologiques › Démographie › État de santé › Qualité de vie › Changes in oral function, swallowing function,...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Enquêtes et questionnaires › Changes in oral function, swallowing function,...