Quality assurance of a breathing controlled four-dimensional computed tomography algorithm.

4DCT Quality assurance Respiratory motion

Journal

Physics and imaging in radiation oncology
ISSN: 2405-6316
Titre abrégé: Phys Imaging Radiat Oncol
Pays: Netherlands
ID NLM: 101704276

Informations de publication

Date de publication:
Jul 2022
Historique:
received: 17 02 2022
revised: 01 06 2022
accepted: 20 06 2022
entrez: 18 7 2022
pubmed: 19 7 2022
medline: 19 7 2022
Statut: epublish

Résumé

Four-dimensional computed tomography (4DCT) scans are standardly used for radiotherapy planning of tumors subject to respiratory motion. Based on online analysis and automatic adaption of scan parameters to the patient's individual breathing pattern, a new breathing-controlled 4DCT (i4DCT) algorithm attempts to counteract irregular breathing and thus prevent artifacts. The aim of this study was to perform an initial quality assurance for i4DCT. To validate the i4DCT algorithm, phantom measurements were performed to evaluate geometric accuracy (diameter, volume, eccentricity), image quality (dose-normalized contrast-noise-ratio, CT number accuracy), and correct representation of motion amplitude of simulated tumor lesions. Furthermore, the impact of patient weight and resulting table flexion on the measurements was investigated. Static three-dimensional CT (3DCT) scans were used as ground truth. The median volume deviation magnitude between 4DCT and 3DCT was < 2% (<0.2 cm The breathing-controlled algorithm provides in general good results regarding image quality, geometric accuracy, and correct depiction of motion amplitude for regular and irregular breathing.

Sections du résumé

Background & purpose UNASSIGNED
Four-dimensional computed tomography (4DCT) scans are standardly used for radiotherapy planning of tumors subject to respiratory motion. Based on online analysis and automatic adaption of scan parameters to the patient's individual breathing pattern, a new breathing-controlled 4DCT (i4DCT) algorithm attempts to counteract irregular breathing and thus prevent artifacts. The aim of this study was to perform an initial quality assurance for i4DCT.
Material & methods UNASSIGNED
To validate the i4DCT algorithm, phantom measurements were performed to evaluate geometric accuracy (diameter, volume, eccentricity), image quality (dose-normalized contrast-noise-ratio, CT number accuracy), and correct representation of motion amplitude of simulated tumor lesions. Furthermore, the impact of patient weight and resulting table flexion on the measurements was investigated. Static three-dimensional CT (3DCT) scans were used as ground truth.
Results UNASSIGNED
The median volume deviation magnitude between 4DCT and 3DCT was < 2% (<0.2 cm
Conclusions UNASSIGNED
The breathing-controlled algorithm provides in general good results regarding image quality, geometric accuracy, and correct depiction of motion amplitude for regular and irregular breathing.

Identifiants

pubmed: 35844256
doi: 10.1016/j.phro.2022.06.007
pii: S2405-6316(22)00055-0
pmc: PMC9283927
doi:

Types de publication

Journal Article

Langues

eng

Pagination

85-91

Informations de copyright

© 2022 The Author(s).

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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Auteurs

Juliane Szkitsak (J)

Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Erlangen, Germany.

Andre Karius (A)

Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Erlangen, Germany.

Christian Hofmann (C)

Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Siemens Healthcare GmbH, 91301 Forchheim, Germany.

Rainer Fietkau (R)

Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Erlangen, Germany.

Christoph Bert (C)

Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Erlangen, Germany.

Stefan Speer (S)

Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Erlangen, Germany.

Classifications MeSH