Subjective Cognitive Decline: Is a Resilient Personality Protective Against Progression to Objective Cognitive Impairment? Findings from Two Community-Based Cohort Studies.
Conscientiousness
neuroticism
progression to cognitive impairment
resilient personality
subjective cognitive decline
Journal
Journal of Alzheimer's disease : JAD
ISSN: 1875-8908
Titre abrégé: J Alzheimers Dis
Pays: Netherlands
ID NLM: 9814863
Informations de publication
Date de publication:
2022
2022
Historique:
pubmed:
19
7
2022
medline:
9
9
2022
entrez:
18
7
2022
Statut:
ppublish
Résumé
Subjective cognitive decline (SCD) is related to personality functioning and risk of subsequent objective cognitive impairment. The aim of this study was to examine whether lower neuroticism and higher conscientiousness-resilient personality traits-protect against conversion from SCD to objective cognitive impairment in two longitudinal community-based cohorts. Data from the Health and Retirement Study (N = 1,741, Mean age = 68.64 years, Follow-up mean = 7.34 years) and the National Health and Aging Trends Survey (N = 258, Mean age = 79.34 years, Follow-up mean = 4.31 years) were analyzed using Cox regression analysis, controlling for sociodemographic covariates, symptoms of anxiety and depression, and apolipoprotein ɛ4. The pooled results showed that lower neuroticism and higher conscientiousness were associated with decreased risk of conversion from SCD to objective cognitive impairment. Among individuals with SCD, those with a resilient personality may have more cognitive and psychological reserve to maintain cognitive functioning and delay conversion to objective cognitive impairment. The findings further contribute to a better understanding of personality along the cognitive continuum: The observed effect sizes were smaller than those reported in cognitively normal individuals but larger than in individuals with mild cognitive impairment. Personality could provide useful information to identify individuals with SCD who may develop objective cognitive impairment-namely those who hold a vulnerable personality (higher neuroticism, lower conscientiousness).
Sections du résumé
BACKGROUND
Subjective cognitive decline (SCD) is related to personality functioning and risk of subsequent objective cognitive impairment.
OBJECTIVE
The aim of this study was to examine whether lower neuroticism and higher conscientiousness-resilient personality traits-protect against conversion from SCD to objective cognitive impairment in two longitudinal community-based cohorts.
METHODS
Data from the Health and Retirement Study (N = 1,741, Mean age = 68.64 years, Follow-up mean = 7.34 years) and the National Health and Aging Trends Survey (N = 258, Mean age = 79.34 years, Follow-up mean = 4.31 years) were analyzed using Cox regression analysis, controlling for sociodemographic covariates, symptoms of anxiety and depression, and apolipoprotein ɛ4.
RESULTS
The pooled results showed that lower neuroticism and higher conscientiousness were associated with decreased risk of conversion from SCD to objective cognitive impairment.
CONCLUSION
Among individuals with SCD, those with a resilient personality may have more cognitive and psychological reserve to maintain cognitive functioning and delay conversion to objective cognitive impairment. The findings further contribute to a better understanding of personality along the cognitive continuum: The observed effect sizes were smaller than those reported in cognitively normal individuals but larger than in individuals with mild cognitive impairment. Personality could provide useful information to identify individuals with SCD who may develop objective cognitive impairment-namely those who hold a vulnerable personality (higher neuroticism, lower conscientiousness).
Identifiants
pubmed: 35848026
pii: JAD220319
doi: 10.3233/JAD-220319
pmc: PMC9843496
mid: NIHMS1863670
doi:
Substances chimiques
Apolipoprotein E4
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
87-105Subventions
Organisme : NIA NIH HHS
ID : R01 AG053297
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG068093
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG009740
Pays : United States
Références
Acta Psychiatr Scand. 2014 Dec;130(6):439-51
pubmed: 25219393
Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):
pubmed: 33558417
Disabil Rehabil. 2020 Dec;42(25):3606-3613
pubmed: 31074659
Neuroepidemiology. 2005;25(4):181-91
pubmed: 16103729
J Res Pers. 2010 Aug 1;44(4):501-511
pubmed: 21278818
Am J Geriatr Psychiatry. 2015 Sep;23(9):985-93
pubmed: 25746485
BMJ Open. 2018 Jul 19;8(7):e021610
pubmed: 30030318
Psychol Aging. 2014 Dec;29(4):828-42
pubmed: 25089853
Int J Geriatr Psychiatry. 2012 Apr;27(4):394-400
pubmed: 21560161
Int J Epidemiol. 2019 Aug 1;48(4):1044-1045g
pubmed: 31237935
Alzheimers Dement. 2018 Apr;14(4):535-562
pubmed: 29653606
J Pers Soc Psychol. 2023 Feb;124(2):381-395
pubmed: 35404649
Lancet Neurol. 2012 Nov;11(11):1006-12
pubmed: 23079557
Neurology. 2001 Jan 9;56(1):37-42
pubmed: 11148233
BMC Psychiatry. 2015 Jul 03;15:146
pubmed: 26138700
Int Psychogeriatr. 2005 Sep;17(3):499-512
pubmed: 16252381
J Gerontol B Psychol Sci Soc Sci. 2016 Jul;71(4):591-601
pubmed: 25583598
J Aging Health. 1997 May;9(2):171-84
pubmed: 10182402
Alzheimers Dement. 2014 Nov;10(6):844-52
pubmed: 24798886
J Pers Soc Psychol. 2007 Dec;93(6):1080-107
pubmed: 18072856
Psychol Aging. 2011 Jun;26(2):351-62
pubmed: 20973606
J Alzheimers Dis. 2018;63(4):1523-1535
pubmed: 29782316
J Alzheimers Dis. 2015;46(3):805-12
pubmed: 25854926
Brain Imaging Behav. 2020 Dec;14(6):2122-2131
pubmed: 31486975
J Int Neuropsychol Soc. 2020 Jul;26(6):596-606
pubmed: 31822309
J Int Neuropsychol Soc. 2016 Aug;22(7):765-76
pubmed: 27346168
Alzheimers Dement. 2019 Mar;15(3):465-476
pubmed: 30555032
Psychol Bull. 2004 Nov;130(6):887-919
pubmed: 15535742
Psychosomatics. 2009 Nov-Dec;50(6):613-21
pubmed: 19996233
JAMA Intern Med. 2017 Jan 1;177(1):51-58
pubmed: 27893041
Collabra Psychol. 2020;6(1):
pubmed: 33354648
J Gerontol B Psychol Sci Soc Sci. 2011 Jul;66 Suppl 1:i162-71
pubmed: 21743047
Neurology. 2018 Jul 24;91(4):e300-e312
pubmed: 29959257
Alzheimers Dement. 2016 Mar;12(3):292-323
pubmed: 27012484
J Res Pers. 2021 Jun;92:
pubmed: 34083845
Dev Psychol. 2014 May;50(5):1426-41
pubmed: 23978300
Int J Geriatr Psychiatry. 2016 Oct;31(10):1105-15
pubmed: 27441851
J Consult Clin Psychol. 1988 Dec;56(6):893-7
pubmed: 3204199
Am J Geriatr Psychiatry. 2012 Dec;20(12):1026-35
pubmed: 23079898
PLoS One. 2019 Jul 15;14(7):e0219712
pubmed: 31306444
Psychol Med. 2018 Apr;48(6):974-982
pubmed: 28874220
JAMA Psychiatry. 2017 Dec 1;74(12):1259-1265
pubmed: 28975188
Psychol Aging. 2017 May;32(3):259-277
pubmed: 28230383
BMJ. 1998 Apr 18;316(7139):1236-8
pubmed: 9553006
Alzheimers Dement. 2021 Mar;17(3):327-406
pubmed: 33756057
JAMA Psychiatry. 2020 Feb 1;77(2):148-154
pubmed: 31617877
BMC Psychol. 2018 May 21;6(1):23
pubmed: 29784047
J Psychiatr Res. 2018 May;100:1-4
pubmed: 29471080
J Pers Soc Psychol. 2017 Jul;113(1):117-143
pubmed: 27055049
Ageing Res Rev. 2021 May;67:101269
pubmed: 33561581
Alzheimers Dement. 2015 Jun;11(6):718-26
pubmed: 26045020
Hum Brain Mapp. 2021 Jan;42(1):192-203
pubmed: 33030795
J Alzheimers Dis. 2015 Sep 24;48 Suppl 1:S63-86
pubmed: 26402085
J Alzheimers Dis. 2018;65(1):303-320
pubmed: 30040718
Psychol Sci. 2017 Sep;28(9):1345-1357
pubmed: 28703694
Psychol Bull. 1968 Sep;70(3):151-9
pubmed: 5681305
J Clin Neurosci. 2022 Apr;98:60-65
pubmed: 35131726
BMC Public Health. 2021 Jun 24;21(1):1173
pubmed: 34162356
Biol Psychiatry. 2022 Feb 15;91(4):359-369
pubmed: 34663503
Neuroepidemiology. 2019;52(1-2):86-92
pubmed: 30602170
J Res Pers. 2016 Aug;63:22-28
pubmed: 29056783
Int J Geriatr Psychiatry. 2009 Feb;24(2):190-6
pubmed: 18642390
Int J Geriatr Psychiatry. 2015 Jun;30(6):623-30
pubmed: 25145943
J Alzheimers Dis. 2018;63(3):949-956
pubmed: 29689718
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2015;22(1):42-71
pubmed: 24580119
Collabra Psychol. 2020;6(1):
pubmed: 33073161
J Psychiatr Res. 2017 Jun;89:22-27
pubmed: 28153642
J Gerontol B Psychol Sci Soc Sci. 2021 Jan 1;76(1):6-19
pubmed: 32969474
J Pers. 2000 Dec;68(6):1089-107
pubmed: 11130733
Am Psychol. 2009 May-Jun;64(4):241-56
pubmed: 19449983
J Public Health (Oxf). 2014 Sep;36(3):382-9
pubmed: 24167198
Int J Geriatr Psychiatry. 2021 Aug;36(8):1188-1196
pubmed: 33555636
Collabra Psychol. 2020;6(1):
pubmed: 33354649
Prog Neurobiol. 2011 Dec;95(4):594-600
pubmed: 21925234
Alzheimers Res Ther. 2020 Dec 18;12(1):167
pubmed: 33339532
J Clin Exp Neuropsychol. 2012;34(6):598-605
pubmed: 22384819
Alzheimers Dement. 2017 Mar;13(3):296-311
pubmed: 27825022
Psychol Aging. 2022 Aug;37(5):575-590
pubmed: 35113607
Neurobiol Aging. 2013 Apr;34(4):1045-50
pubmed: 23040035
J Prev Alzheimers Dis. 2022;9(3):435-440
pubmed: 35841244
Int J Geriatr Psychiatry. 2017 May;32(5):564-573
pubmed: 27162047
Alzheimers Res Ther. 2019 Jul 8;11(1):61
pubmed: 31286994
Disabil Rehabil. 2019 Jan;41(1):19-25
pubmed: 28849674
Personal Disord. 2019 Jan;10(1):4-12
pubmed: 30604979
Br J Psychol. 2014 Nov;105(4):564-80
pubmed: 24182200
Psychosom Med. 2007 Jan;69(1):47-53
pubmed: 17244848
Psychother Psychosom. 2010;79(1):6-19
pubmed: 19887887
Lancet Neurol. 2020 Mar;19(3):271-278
pubmed: 31958406
Alzheimers Dement. 2011 May;7(3):280-92
pubmed: 21514248