Fish oil blunts lung function decrements induced by acute exposure to ozone in young healthy adults: A randomized trial.

Air Pollutants / pharmacology Female Fish Oils / pharmacology Humans Lung Male Ozone / adverse effects Respiratory Function Tests
Cardiovascular effects Fish oil Olive oil Ozone Pulmonary effects

Journal

Environment international
ISSN: 1873-6750
Titre abrégé: Environ Int
Pays: Netherlands
ID NLM: 7807270

Informations de publication

Date de publication:
09 2022
Historique:
received: 07 03 2022
revised: 06 07 2022
accepted: 08 07 2022
pubmed: 20 7 2022
medline: 17 8 2022
entrez: 19 7 2022
Statut: ppublish

Résumé

Over one-third of the U.S. population is exposed to unsafe levels of ozone (O Forty-three participants (26 ± 4 years old; 47% female) were randomized to receive 3 g/day of FO, 3 g/day OO, or no supplementation (CTL) for 4 weeks prior to undergoing 2-hour exposures to filtered air and 300 ppb O Compared with filtered air, O FO supplementation appears to offer protective effects against lung function decrements caused by acute O

Sections du résumé

BACKGROUND
Over one-third of the U.S. population is exposed to unsafe levels of ozone (O
METHODS
Forty-three participants (26 ± 4 years old; 47% female) were randomized to receive 3 g/day of FO, 3 g/day OO, or no supplementation (CTL) for 4 weeks prior to undergoing 2-hour exposures to filtered air and 300 ppb O
RESULTS
Compared with filtered air, O
CONCLUSION
FO supplementation appears to offer protective effects against lung function decrements caused by acute O

Identifiants

DOI: 10.1016/j.envint.2022.107407 PMID: 35850080 PMC: PMC9378480
pubmed: 35850080
pii: S0160-4120(22)00334-8
doi: 10.1016/j.envint.2022.107407
pmc: PMC9378480
mid: NIHMS1826155
pii:
doi:

Substances chimiques

Air Pollutants 0
Fish Oils 0
Ozone 66H7ZZK23N

Types de publication

Journal Article Randomized Controlled Trial Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

107407

Subventions

Organisme : Intramural EPA
ID : EPA999999
Pays : United States
Organisme : NIEHS NIH HHS
ID : P30 ES010126
Pays : United States

Informations de copyright

Published by Elsevier Ltd.

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Auteurs

Hao Chen (H)

Oak Ridge Institute for Science and Education, Oak Ridge, TN, United States.

Haiyan Tong (H)

Public Health and Integrated Toxicology Division, Center for Public Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Chapel Hill, NC, United States.

Wan Shen (W)

Oak Ridge Institute for Science and Education, Oak Ridge, TN, United States; Department of Public and Allied Health, Bowling Green State University, Bowling Green, OH, United States.

Tracey S Montilla (TS)

Public Health and Integrated Toxicology Division, Center for Public Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Chapel Hill, NC, United States.

Martin W Case (MW)

Public Health and Integrated Toxicology Division, Center for Public Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Chapel Hill, NC, United States.

Martha A Almond (MA)

Center for Environmental Medicine, Asthma and Lung Biology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.

Heather B Wells (HB)

Center for Environmental Medicine, Asthma and Lung Biology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Department of Pediatrics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.

Neil E Alexis (NE)

Center for Environmental Medicine, Asthma and Lung Biology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Department of Pediatrics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.

David B Peden (DB)

Center for Environmental Medicine, Asthma and Lung Biology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Department of Pediatrics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.

Ana G Rappold (AG)

Public Health and Integrated Toxicology Division, Center for Public Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Chapel Hill, NC, United States.

David Diaz-Sanchez (D)

Public Health and Integrated Toxicology Division, Center for Public Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Chapel Hill, NC, United States.

Robert B Devlin (RB)

Public Health and Integrated Toxicology Division, Center for Public Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Chapel Hill, NC, United States.

Philip A Bromberg (PA)

Center for Environmental Medicine, Asthma and Lung Biology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.

James M Samet (JM)

Public Health and Integrated Toxicology Division, Center for Public Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Chapel Hill, NC, United States. Electronic address: Samet.James@epa.gov.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Polluants environnementaux › Polluants atmosphériques › Fish oil blunts lung function decrements...
questionsmedicales.fr › Lipides › Huiles › Huiles de poisson › Fish oil blunts lung function decrements...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Fish oil blunts lung function decrements...
questionsmedicales.fr › Appareil respiratoire › Poumon › Fish oil blunts lung function decrements...
questionsmedicales.fr › Produits chimiques inorganiques › Gaz › Oxygène › Ozone › Fish oil blunts lung function decrements...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic respiratoire › Tests de la fonction respiratoire › Fish oil blunts lung function decrements...