The Antifungal and Anti-Pneumocystis Activities of the Novel Compound A3IS (Mycosinate).


Journal

Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061

Informations de publication

Date de publication:
16 08 2022
Historique:
pubmed: 20 7 2022
medline: 19 8 2022
entrez: 19 7 2022
Statut: ppublish

Résumé

A3IS (Mycosinate) is a synthetic product which only contains ingredients found naturally within honey. A3IS is a broad-spectrum antimicrobial product which produces a sustained release of hydrogen peroxide at low but therapeutic levels. The product elicits this release through an enzymatic reaction between glucose oxidase and the substrate glucose once the product is hydrated. As medical uses for different honeys are being re-evaluated, the purpose of this study was to evaluate the

Identifiants

pubmed: 35852368
doi: 10.1128/aac.00521-22
pmc: PMC9380569
doi:

Substances chimiques

Antifungal Agents 0
Fluconazole 8VZV102JFY
Voriconazole JFU09I87TR

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0052122

Subventions

Organisme : CLC NIH HHS
ID : 75N90019D00022
Pays : United States
Organisme : ORFDO NIH HHS
ID : 75N99019D00022
Pays : United States
Organisme : BLRD VA
ID : IK6 BX005232
Pays : United States
Organisme : HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
ID : 75N93019D00022/75N93021F00001

Commentaires et corrections

Type : ErratumIn

Références

Sci Rep. 2019 Dec 3;9(1):18197
pubmed: 31796803
J Med Microbiol. 2016 Apr;65(4):337-344
pubmed: 26861950
Mycopathologia. 2021 Oct;186(5):665-672
pubmed: 34268702
mSystems. 2020 Jun 30;5(3):
pubmed: 32606022
Expert Opin Pharmacother. 2021 Aug;22(12):1579-1592
pubmed: 33870843
Eur J Med Chem. 2019 Oct 1;179:623-633
pubmed: 31279295
Antibiotics (Basel). 2020 Oct 31;9(11):
pubmed: 33142845
Pharmaceuticals (Basel). 2021 Dec 16;14(12):
pubmed: 34959712
Curr Med Chem. 2009;16(20):2514-30
pubmed: 19601796
J Food Sci Technol. 2011 Oct;48(5):640-3
pubmed: 23572800
Antimicrob Agents Chemother. 2006 Jul;50(7):2337-43
pubmed: 16801410
Lett Appl Microbiol. 2020 Sep;71(3):251-258
pubmed: 32357252
BMC Infect Dis. 2021 Jul 7;21(1):659
pubmed: 34233631
Mol Neurobiol. 2021 Oct;58(10):4980-4998
pubmed: 34228268
Semin Cancer Biol. 2017 Oct;46:84-106
pubmed: 28676460
Molecules. 2013 Apr 11;18(4):4233-46
pubmed: 23579991

Auteurs

Nathan P Wiederhold (NP)

Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center, San Antonio, Texas, USA.

Thomas F Patterson (TF)

Department of Medicine, The University of Texas Health Science Center, San Antonio, Texas, USA.
South Texas Veterans Health Care System, San Antonio, Texas, USA.

Sandra Rebholz (S)

Department of Internal Medicine, University of Cincinnatigrid.24827.3b College of Medicine, Cincinnati, Ohio, USA.
Medical Research Service, Cincinnati Veterans Affairs Medical Center, Cincinnati, Ohio, USA.

Connell W C Boal (CWC)

Nektr Technologies Ltd., Finisklin Business Park, Sligo, Ireland.

Monika Ehrensberger (M)

Nektr Technologies Ltd., Finisklin Business Park, Sligo, Ireland.

Ryan Boyle (R)

Nektr Technologies Ltd., Finisklin Business Park, Sligo, Ireland.

Melanie T Cushion (MT)

Department of Internal Medicine, University of Cincinnatigrid.24827.3b College of Medicine, Cincinnati, Ohio, USA.
Medical Research Service, Cincinnati Veterans Affairs Medical Center, Cincinnati, Ohio, USA.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH