Childhood behavioral inhibition and overcontrol: Relationships with cognitive functioning, error monitoring, anxiety and obsessive-compulsive symptoms.

Behavioral inhibition Error-related negativity OCD Overcontrol Pediatric anxiety Performance monitoring

Journal

Research on child and adolescent psychopathology
ISSN: 2730-7174
Titre abrégé: Res Child Adolesc Psychopathol
Pays: United States
ID NLM: 101773609

Informations de publication

Date de publication:
12 2022
Historique:
accepted: 20 06 2022
pubmed: 20 7 2022
medline: 16 11 2022
entrez: 19 7 2022
Statut: ppublish

Résumé

Anxiety and obsessive-compulsive disorders are common childhood psychiatric disorders. Behavioral inhibition (BI) is a widely studied risk factor for anxiety. Less is known about overcontrol, a related behavioral phenotype characterized by concern for errors, perfectionism, and inflexibility and also associated with anxiety and obsessive-compulsive disorder. Both BI and overcontrol show associations with aberrant cognitive control and neural error responding (via the error-related negativity; ERN) yet it is unknown whether each imparts differential risk. Understanding whether overcontrol demonstrates independent associations from BI with cognitive functioning, neural error monitoring, and childhood anxiety and obsessive-compulsive presentations could aid in identifying a novel mechanistic treatment target. We assessed BI, overcontrol, cognitive functioning and psychopathology in a cross-sectional sample of 5-6 year old children (N = 126). Children completed an electroencephalogram (EEG) to assess the ERN. Overcontrol was associated with worse cognitive shifting, worse inhibitory control and higher anxiety and obsessive-compulsive symptoms, beyond BI. BI was associated with worse cognitive shifting, better inhibitory control and higher anxiety symptoms, beyond overcontrol. When assessed simultaneously, only overcontrol demonstrated a significant relationship with a blunted ERN. Moreover, overcontrol mediated (cross-sectionally) the well-established relationship between ERN and anxiety and obsessive-compulsive symptoms. BI and overcontrol impart differential risk for child cognitive functioning and anxiety while overcontrol demonstrates additional risk for aberrant neural error monitoring, anxiety and obsessive-compulsive presentations. Overcontrol may also be a mechanistic pathway between the ERN and transdiagnostic anxiety and obsessive-compulsive symptoms. Overcontrol may be a target warranted for early-childhood intervention in anxiety and OCD.

Identifiants

pubmed: 35852701
doi: 10.1007/s10802-022-00953-x
pii: 10.1007/s10802-022-00953-x
pmc: PMC9906714
mid: NIHMS1859899
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

1629-1642

Subventions

Organisme : NIMH NIH HHS
ID : K23 MH115074
Pays : United States

Commentaires et corrections

Type : ErratumIn

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Auteurs

Kirsten Gilbert (K)

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA. gilbertk@wustl.edu.

Ella Sudit (E)

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.

Nathan A Fox (NA)

Department of Human Development and Quantitative Methodology, University of Maryland, College Park, Maryland, USA.

Deanna M Barch (DM)

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
Department of Psychological & Brain Sciences, Washington University in St. Louis, St. Louis, MO, USA.
Department of Radiology, Washington University in St. Louis, St. Louis, MO, USA.

Joan L Luby (JL)

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.

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