Invasive Aspergillus infection of middle ear in a patient treated with secukinumab, methotrexate, and corticosteroids for psoriasis and psoriatic arthritis.


Journal

The Journal of dermatological treatment
ISSN: 1471-1753
Titre abrégé: J Dermatolog Treat
Pays: England
ID NLM: 8918133

Informations de publication

Date de publication:
Nov 2022
Historique:
pubmed: 21 7 2022
medline: 10 11 2022
entrez: 20 7 2022
Statut: ppublish

Résumé

Mucocutaneous mycotic infections are common complications in patients on IL-17 inhibitor therapy. We report a case of a 33-year-old male with severe psoriasis and psoriatic arthritis on secukinumab combined with methotrexate and prednisone with swelling, otorrhea, and pain of the right ear and external auditory canal. Due to progressive hypacusis, a surgical solution was chosen. Tissue samples taken during surgery revealed the presence of

Identifiants

pubmed: 35856655
doi: 10.1080/09546634.2022.2104442
doi:

Substances chimiques

secukinumab DLG4EML025
Methotrexate YL5FZ2Y5U1
Adrenal Cortex Hormones 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3063-3065

Auteurs

Filip Rob (F)

Department of Dermatovenereology, Second Faculty of Medicine, Charles University, Bulovka University Hospital, Prague, Czech Republic.

Lukáš Školoudík (L)

Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Hradec Králové, Charles University, Faculty of Medicine in Hradec Králové, Hradec Králové, Czech Republic.

Viktor Chrobok (V)

Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Hradec Králové, Charles University, Faculty of Medicine in Hradec Králové, Hradec Králové, Czech Republic.

Jana Dědková (J)

Department of Radiology, University Hospital Hradec Králové, Hradec Králové, Czech Republic.

Petra Kašparová (P)

The Fingerland Department of Pathology, University Hospital Hradec Králové, Charles University, Faculty of Medicine in Hradec Králové, Hradec Králové, Czech Republic.

Lucie Podrazilová (L)

Department of Rheumatology, Revma Praha, Prague, Czech Republic.

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Classifications MeSH