Dementia, a Polypharmaceutical Phenomenon: The Intimate Combinations of Dementia Drugs in Brazil.
Dementia
Ethnography
Geriatrics
Intra-action
Polypharmacy
Journal
Culture, medicine and psychiatry
ISSN: 1573-076X
Titre abrégé: Cult Med Psychiatry
Pays: Netherlands
ID NLM: 7707467
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
accepted:
01
06
2022
medline:
9
8
2023
pubmed:
21
7
2022
entrez:
20
7
2022
Statut:
ppublish
Résumé
It is commonplace to state that dementia is a complex condition. Such complexity involves the limits between pathological and normal aging, diagnosis with no simple organic causation, and the use of psychiatric medication that does not cure but generates hope to alleviate symptoms such as forgetfulness and delirium. Based on an ethnography of one year and a half (2017-2018) in a Brazilian metropolis, within a Public Geriatric center and the households of three families, I argue that dementia, more than a complex condition, is a generator of drug complexity. Following Stefan Ecks' reflections on multimorbidity and polyiatrogenesis and Karen Barad's understanding of intra-action, I discuss the polypharmacy present in most cases of dementia that I have known. Considering the complicated relations of medications with themselves and with time and places, I conclude that dementia should be seen a polypharmaceutical phenomenon.
Identifiants
pubmed: 35857155
doi: 10.1007/s11013-022-09793-2
pii: 10.1007/s11013-022-09793-2
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
814-833Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Références
Akrich, Madeleine 1995 Petite anthropologie du médicament. Techniques Et Cultures 25–26: 129–157. https://doi.org/10.4000/tc.511
Ballenger, Jesse, Peter Whitehouse, Constantine Lyketsos, Peter Rabins, and Jason Karlawish 2009 Treating Dementia: Do We Have a Pill For It? Baltimore: The Johns Hopkins University Press
Ballenger, Jesse 2006 The Biomedical Deconstruction of Senility and the Persistent Stigmatization of Old Age in the United States. In Thinking About Dementia: Culture, Loss, and the Anthropology of Senility Annette Leibing, and Lawrence Cohen, eds., New Jersey: Rutgers University Press.
Barad, Karen 2003 Posthumanist Performativity: Toward an Understanding of How Matter Comes to Matter. Signs Journal of Women in Culture and Society 28(3): 801–831. https://doi.org/10.1086/345321
Barry, Andrew 2003 Pharmaceutical Matters: The Invention of Informed Materials. Theory, Culture & Society 22(1): 51–69. https://doi.org/10.1177/0263276405048433
Biehl, João., and Adriana Petryna 2011 Bodies of Rights and Therapeutic Markets. Social Research 78(2): 359–386
Biehl, João. 2005 Vita: Life in a Zone of Social Abandonment Berkeley: University of California Press
Blum, Linda 2011 ‘Not This Big, Huge, Racial-Type Thing, but…’: Mothering Children of Color with Invisible Disabilities in the Age of Neuroscience. Signs 36(4): 941–967. https://doi.org/10.1086/658503.iv
Castro, Rosana 2020 Economias políticas da doença e da saúde: uma etnografia da experimentação farmacêutica São Paulo: Hucitec Editora
Chua, Jocelyn 2020 Medication by Proxy: The Devolution of Psychiatric Power and Shared Accountability to Psychopharmaceutical Use Among Soldiers in America’s Post-9/11 Wars. Culture, Medicine and Psychiatry 44: 565–585. https://doi.org/10.1007/s11013-020-09673-7
Cohen, Lawrence 2006 Introduction: Thinking About Dementia. In Thinking About Dementia: Culture, Loss, and the Anthropology of Senility Annette Leibing, and Lawrence Cohen, eds., New Jersey: Rutgers University Press.
Das, Veena 2015 Affliction: health, disease, poverty New York: Fordham University Press
Das, Veena, and Ranendra Das 2006 Pharmaceuticals in Urban Ecologies the Register of the Local. In Global Pharmaceuticals: Ethics, Markets, Practices Adriana Petryna, Andrew Lakoff, and Arthur Kleinman, eds., North Carolina: Duke University Press.
Dodier, Nicolas 2005 Transnational Medicine in Public Arenas: Aids Treatments in the South. Culture, Medicine and Psychiatry 29: 285–307. https://doi.org/10.1007/s11013-005-9169-2
Ecks, Stefan 2021 Depression, Deprivation, and Dysbiosis: Polyiatrogenesis in Multiple Chronic Illnesses. Culture, Medicine and Psychiatry 45: 507–524. https://doi.org/10.1007/s11013-020-09699-x
Ecks, Stefan 2014 Eating Drugs Psychopharmaceutical Pluralism in India New York: New York University Press
Engel, Cíntia. 2019 Óleo de coco, banha de porco, prazer de comer e os deslizamentos do saudável: manejos de versões da Doença de Alzheimer a partir de terapias alimentares. Aceno – Revista De Antropologia Do Centro-Oeste 6: 57–74. https://doi.org/10.48074/aceno.v6i12.8935
Featherstone, Katie, and Andy Northcott 2020 Wandering the Wards: An Ethnography of Hospital Care and Its Consequences for People Living with Dementia London: Routledge
Fisher, Jill 2020 Adverse Events: Race, Inequality, and the Testing of New Pharmaceuticals, (Vol. 9). New York: New York University Press
Fleischer, Soraya 2021 Uso e circulação de medicamentos em um bairro popular urbano na Ceilândia, DF. Saude Soc 21(2): 410–423. https://doi.org/10.1590/S0104-12902012000200014
Flicker, Leon 2002 Efficacy of Pharmacological Treatment of Dementia. Revista Brasileira De Psiquiatria 24(1): 11–14. https://doi.org/10.1590/S1516-44462002000500004
Fox, Patrick 1989 From Senility to Alzheimer Disease: The Rise of the Alzheimer Disease Movement. Milbank Quarterly 67(58): 58–102
Graham, Janice 2006 Diagnosing Dementia: Epidemiological and Clinical Data as Cultural Text. In Thinking About Dementia: Culture, Loss, and the Anthropology of Senility Annette Leibing, and Lawrence Cohen, eds., New Jersey: Rutgers University Press.
Greenslit, Nathan 2005 Depression and Consumption: Psychopharmaceuticals, Branding, and New Identity Practices. Culture, Medicine and Psychiatry 29(4): 477–502. https://doi.org/10.1007/s11013-006-9005-3
Hardon, Anita, and Emilia Sanabria 2017 Fluid Drugs: Revisiting the Anthropology of Pharmaceuticals. Annual Review of Anthropology 46: 117–132. https://doi.org/10.1146/annurev-anthro-102116-041539
Hayden, Cori 2007 A Generic Solution? Pharmaceuticals and the Politics of the Similar in Mexico. Current Anthropology 48(2): 475–495. https://doi.org/10.1086/518301
Hayden, Cori 2012 Rethinking Reductionism or the Transformative Work of Making the Same. Anthropology Forum 22(3): 271–283. https://doi.org/10.1080/00664677.2012.711240
Healy, David 2006 Manufacturing Consensus. Culture, Medicine and Psychiatry 30: 135–156. https://doi.org/10.1007/s11013-006-9013-3
Hinton, Devon, and Byron Good, eds. 2016 Culture and PTSD: Trauma in Global and Historical Perspective. Philadelphia: University of Pennsylvania Press.
Ingold, Tim 2010 “Bringing Things to Life: Creative Entanglements in a World of Materials.” ESRC National Centre for Research Methods. Realities 15: 1–14
Jellinger, Kurt 2010 Should the Word “Dementia” be Forgotten? Journal of Cellular and Molecular Medicine 14(10): 2415–2416. https://doi.org/10.1111/j.1582-4934.2010.01159.x
Jenkins, Janis 2010 Pharmaceutical Self: The Global Shaping of Experience in an Age of Psychopharmacology Santa Fe: School for Advanced Research Press
Kitanaka, Junko 2012 Depression in Japan: Psychiatric Cures for a Society in Distress New Jersey: Princeton University Press
Kontos, Pia 2005 Embodied selfhood in Alzheimer’s disease: Rethinking person-centred care. Dementia 4(4): 553–570. https://doi.org/10.1177/1471301205058311
Kopytoff, Igor 1986 The cultural biography of things: commoditization as process. In The Social Life of Things: Commodities in Cultural Perspective Arjun Appadurai, ed., Cambridge: Cambridge University Press.
Leibing, Annette, Cíntia. Engel, and Elisângela Carrijo 2019 Life Through Medications: Dementia Care in Brazil. ReVista - Harvard Review of Latin America. Aging in the Americas (winter 2019) / Part Ii: Facing the Challenges 18: 1–6
Leibing, Annette, and Silke Schicktanz 2020 Preventing Dementia? Critical Perspectives on a New Paradigm of Preparing for Old Age New York: Berghahn
Leibing, Annette 1999 Olhando para trás: os dois nascimentos da doença de Alzheimer e a senilidade no Brasil. Estudos Interdisciplinares Envelhecimento 1: 37–56. https://doi.org/10.22456/2316-2171.4650
Leibing, Annette 2009a Tense prescriptions? Alzheimer medications and the anthropology of uncertainty. Transcultural Psychiatry 46: 180–206. https://doi.org/10.1177/1363461509102297
Leibing, Annette 2009b From the Periphery to the Center: Treating Noncognitive, Especially Behavioral and Psychological Symptoms of Dementia. In Treating Dementia: Do We Have a Pill For It? Jesse Ballenger, Peter Whitehouse, Constantine Lyketsos, Peter Rabins, and Jason Karlawish, eds., Baltimore: The Johns Hopkins University Press.
Leibing, Annette 2019 Geriatrics and Humanism: Dementia and Fallacies of Care. Journal of Aging Studies 51: 1–7. https://doi.org/10.1016/j.jaging.2019.100796
Lock, Margaret 2005 A mente molecularizada e a busca da demência incipiente. Physis: Revista De Saúde Coletiva 15(2): 205–236
Lock, Margaret 2013 The Alzheimer Conundrum: Entanglements of Dementia and Aging New Jersey: Princeton University Press
Lovell, Anne, Ursula Read, and Claudia Lang 2019 Genealogies and Anthropologies of Global Mental Health. Culture, Medicine and Psychiatry 43: 519–547. https://doi.org/10.1007/s11013-019-09660-7
Manderson, Leonore, and Narelle Warren 2016 ‘Just One Thing after Another’: Recursive Cascades and Chronic Conditions. Med Anthropol 30(4): 479–497. https://doi.org/10.1111/maq.12277
Martinez-Hernaez, Angel 2020 Neuronarratives of Affliction: Antidepressants, Neuropolitics and the ‘Entrepreneur of Oneself.’ Culture, Medicine and Psychiatry 44: 230–248. https://doi.org/10.1007/s11013-019-09651-8
Mol, Annemarie 2008 The Logic of Care: Health and the Problem of Patient Choice New York: Routledge
Mol, Annemarie 2002 The body multiple: ontology in medical practice Durham and London: Duke University Press
Mol, Annemarie, Ingunn Moser, and Jeannette Pols 2010 Care: Putting Practice Into Theory. In Care in Practice: On Tinkering in Clinics, Homes and Farms Annemarie Mol, Ingunn Moser, and Jeannette Pols, eds., Bielefeld: Transcript Verlag.
Moreira, Tiago 2010 Now or Later Individual Disease and Care Collective in the Memory Clinic. In Care in Practice: On Tinkering in Clinics, Homes and Farms Annemarie Mol, Ingunn Moser, and Jeannette Pols, eds., Bielefeld: transcript Verlag.
Morley, John 2004 A Brief History of Geriatrics. Journal of Gerontology: Medical Sciences 59A(11): 1132–1152. https://doi.org/10.1093/gerona/59.11.1132
Mulley, Graham 2012 Hot Topic in Geriatric Medicine: A History of Geriatrics and Gerontology. European Geriatric Medicine 3: 225–227. https://doi.org/10.1016/j.eurger.2012.06.007
Nading, Alex 2014 Local Biologies and the Chemical Infrastructures of Global Heath. Hal 79: 1–17
Ninnemann, Kristi 2012 Variability in the Efficacy of Psychopharmaceuticals: Contributions from Pharmacogenomics, Ethnopsychopharmacology, and Psychological and Psychiatric Anthropologies. Culture, Medicine and Psychiatry 36: 10–25. https://doi.org/10.1007/s11013-011-9242-y
Nunes, Bruno, Sandro Batista, Fabíola Bof, Paulo de Andrade, Borges de Souza, Maria Fernanda Junior, and Lima-Costa, and Luiz Augusto Facchini 2018 Multimorbidity: The Brazilian Longitudinal Study of Aging (ELSI-Brazil). Revista Saúde Pública 52(2): 1–12. https://doi.org/10.11606/S1518-8787.2018052000637
Oldani, Michael 2014 Deep pharma: psychiatry, anthropology, and pharmaceutical detox. Culture, Medicine and Psychiatry 38(2): 255–278. https://doi.org/10.1007/s11013-014-9369-8
Petryna, Adriana 2005 Ethical Variability: Drug Development and Globalizing Clinical Trials. American Ethnologist 32(2): 183–197. https://doi.org/10.1525/ae.2005.32.2.183
Petryna, Adriana 2007 Experimentality: On the Global Mobility and Regulation of Human Subjects Research. Political and Legal Anthropology Review. https://doi.org/10.1525/pol.2007.30.2.288
Petryna, Adriana 2011 Pharmaceuticals and the Right to Health: Reclaiming Patients and the Evidence Base of New Drugs. Anthropological Quarterly 84(2): 305–329. https://doi.org/10.1353/anq.2011.0024
Penido, Alexandre. 2018. “Estudo aponta que 75% dos idosos usam apenas o SUS”. Agência Fiocruz Notícias, October 4, 2018. https://portal.fiocruz.br/noticia/estudo-aponta-que-75-dos-idosos-usam-apenas-o-sus
Pollock, Anne 2019 Synthesizing Hope: Matter, Knowledge, and Place in South African Drug Discovery Chicago: University of Chicago Press
Ramos, Luiz, Noemia TavaresI, Andréa Bertoldi, Mareni Farias, Maria Auxiliadora Oliveira, Vera Lucia Luiza, Tatiane Dal Pizzol, Paulo Sérgio. Arrais, and Sotero Mengue 2016 Polifarmácia e polimorbidade em idosos no Brasil: um desafio em saúde pública. Revista De Saúde Pública 50(2): 1s–13s. https://doi.org/10.1590/S1518-8787.2016050006145
Rose, Nikolas 2003 The Neurochemical Self and Its Anomalies. In Risk and Mortality Richard Ericson, and Aaron Doyle, eds., Toronto: University of Toronto Press.
Rose, Nikolas 2007 The Politics of Life Itself: Biomedicine, Power, and Subjectivity in the Twenty-First Century Princeton and Oxford: Princeton University Press
Saethre, Eirik, and Jonathan Stadler 2013 Malicious Whites, Greedy Women, and Virtuous Volunteers: Negotiating Social Relations through Clinical Trial Narratives in South Africa. Medical Anthropology Quarterly 27(1): 103–120. https://doi.org/10.1111/maq.12018
Sanabria, Emilia 2009 Le medicament, un objet evanescent: essai sur la fabrication et la consommation des substances pharmaceutiques. Tech. Cult. 52–53: 168–189
Secoli, Silvia 2010 Polifarmácia: interações e reações adversas no uso de medicamentos por idosos. Revista Brasileira De Enfermagem 63(1): 136–140. https://doi.org/10.1590/S0034-71672010000100023
Starr, John, and Lawrence Whalley 1994 Drug-Induced Dementia. Incidence, Management and Prevention. Drug Safety 11(5): 310–317. https://doi.org/10.2165/00002018-199411050-00003
Stengers, Isabele 2011 Comparison as a Matter of Concern. Common Knowledge 17(1): 48–63. https://doi.org/10.1215/0961754X-2010-035
Taylor, Janelle 2017 Engaging with Dementia: Moral Experiments in Art and Friendship. Culture, Medicine and Psychiatry 41(2): 284–303. https://doi.org/10.1007/s11013-017-9528-9
Teixeira, Maíra., Lívia. Sá-Barreto, Dayde Silva, and Marcílio Cunha-Filho 2016 Panorama dos aspectos regulatórios que norteiam a partição de comprimidos. Revista Panamericana Salud Publica 39(6): 372–377
Tone, Andrea 2006 From Naughty Goods to Nicole Miller: Medicine and The Marketing of American Contraceptives. Culture, Medicine and Psychiatry 30: 249–267. https://doi.org/10.1007/s11013-006-9015-1
vander Geestsjaak, Susan Whyte, and Anita Hardon 1996 The Anthropology of Pharmaceuticals: A Biographical Approach. Annual Review of Anthropology 25: 153–178
Vidal, Fernando, and Francisco Ortega 2017 Being Brains Making the Cerebral Subject New York: Fordham University Press
Vivien, Walsh, and Jordan Goodman 2002 From Taxol to Taxol: The Changing Identities and Ownership of an Anti-cancer Drug. Medical Anthropology: Cross Cultural Studies in Health and Illness 21(3–4): 307–336
Yahalom, Jonathan 2019 Caring for the People of the Clouds: Aging and Dementia in Oaxaca Norman: University of Oklahoma Press