SARS-CoV-2-Specific Memory B Cell Responses Are Maintained After Recovery from Natural Infection and Postvaccination.
SARS-CoV-2
adaptive immunity
humoral immunity
memory B cell
natural infection
vaccination
Journal
Viral immunology
ISSN: 1557-8976
Titre abrégé: Viral Immunol
Pays: United States
ID NLM: 8801552
Informations de publication
Date de publication:
07 2022
07 2022
Historique:
pubmed:
21
7
2022
medline:
6
8
2022
entrez:
20
7
2022
Statut:
ppublish
Résumé
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory coronavirus 2 (SARS-CoV-2), has resulted in major worldwide disruption and loss of life over the last 2 years. Many research studies have shown waning serological SARS-CoV-2-specific IgG antibody titers over time, yet, it is unclear whether these changes are reflected in the potential functional reactivation of SARS-CoV-2 antigen-specific memory B cells (MBC) populations. This is especially true in the contexts of differing COVID-19 disease severity and after vaccination regimens. This study aimed to investigate these by polyclonal
Identifiants
pubmed: 35857310
doi: 10.1089/vim.2022.0013
doi:
Substances chimiques
Antibodies, Viral
0
Immunoglobulin G
0
Spike Glycoprotein, Coronavirus
0
spike protein, SARS-CoV-2
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
425-436Subventions
Organisme : Department of Health
ID : CS-2016-16-011
Pays : United Kingdom