Neuronal activity induces glucosylceramide that is secreted via exosomes for lysosomal degradation in glia.


Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
15 07 2022
Historique:
entrez: 20 7 2022
pubmed: 21 7 2022
medline: 23 7 2022
Statut: ppublish

Résumé

Recessive variants in

Identifiants

pubmed: 35857503
doi: 10.1126/sciadv.abn3326
pmc: PMC9278864
doi:

Substances chimiques

Glucosylceramides 0
Glucosylceramidase EC 3.2.1.45

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eabn3326

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Auteurs

Liping Wang (L)

Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA.
Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.

Guang Lin (G)

Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.

Zhongyuan Zuo (Z)

Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.

Yarong Li (Y)

Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA.

Seul Kee Byeon (SK)

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.

Akhilesh Pandey (A)

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.
Center for Individualized Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Manipal Academy of Higher Education, Manipal, Karnataka 576 104, India.

Hugo J Bellen (HJ)

Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA.
Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA.

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