Synthesis of odorants in flow and their applications in perfumery.

flow chemistry fragrances odorants scents terpenes

Journal

Beilstein journal of organic chemistry
ISSN: 1860-5397
Titre abrégé: Beilstein J Org Chem
Pays: Germany
ID NLM: 101250746

Informations de publication

Date de publication:
2022
Historique:
received: 08 04 2022
accepted: 09 06 2022
entrez: 21 7 2022
pubmed: 22 7 2022
medline: 22 7 2022
Statut: epublish

Résumé

Continuous flow technology is a key technology for sustainable manufacturing with numerous applications for the synthesis of fine chemicals. In recent years, the preparation of odorants utilizing the advantages of flow reactors received growing attention. In this review, we give an overview of selected methods for the synthesis of odorants in flow, including heterogeneously catalyzed reactions, gas reactions, and photochemical C-H functionalization processes. After a brief introduction on types of odorants, the presented odorant syntheses are ordered according to the main odor families "fruity", "green", "marine", "floral", "spicy", "woody", "ambery", and "musky" and their use and importance for perfumery is briefly discussed.

Identifiants

pubmed: 35859624
doi: 10.3762/bjoc.18.76
pmc: PMC9263551
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

754-768

Informations de copyright

Copyright © 2022, Kleoff et al.

Références

Org Lett. 2021 Jun 4;23(11):4300-4304
pubmed: 33983747
Chemistry. 2010 Oct 11;16(38):11720-5
pubmed: 20821763
Angew Chem Int Ed Engl. 2020 Sep 14;59(38):16310-16344
pubmed: 32453472
ChemSusChem. 2014 Feb;7(2):536-42
pubmed: 24167003
Angew Chem Int Ed Engl. 2018 Sep 10;57(37):12126-12130
pubmed: 30019806
Appl Biochem Biotechnol. 2018 Feb;184(2):630-643
pubmed: 28836237
Acc Chem Res. 2019 Oct 15;52(10):2858-2869
pubmed: 31573791
Beilstein J Org Chem. 2021 May 18;17:1181-1312
pubmed: 34136010
Angew Chem Int Ed Engl. 2021 Sep 1;60(36):19685-19690
pubmed: 34184375
Dalton Trans. 2012 Nov 7;41(41):12666-9
pubmed: 23001219
Chem Biodivers. 2014 Oct;11(10):1629-38
pubmed: 25329788
Angew Chem Int Ed Engl. 2000 Sep 1;39(17):2980-3010
pubmed: 11028024
Chem Rev. 2016 Sep 14;116(17):10276-341
pubmed: 26935706
Angew Chem Int Ed Engl. 2018 Apr 3;57(15):4078-4082
pubmed: 29451725
Angew Chem Int Ed Engl. 2015 Jun 1;54(23):6688-728
pubmed: 25989203
Lab Chip. 2009 Dec 7;9(23):3385-90
pubmed: 19904405
Chem Rev. 2017 Sep 27;117(18):11796-11893
pubmed: 28570059
Angew Chem Int Ed Engl. 2021 Jun 21;60(26):14296-14301
pubmed: 33826212
J Org Chem. 2021 Oct 15;86(20):13924-13933
pubmed: 33899468
Beilstein J Org Chem. 2019 Oct 31;15:2590-2602
pubmed: 31728173
Chemistry. 2020 Jun 18;26(34):7537-7555
pubmed: 32067267

Auteurs

Merlin Kleoff (M)

Freie Universität Berlin, Institut für Chemie und Biochemie, Fabeckstr. 34-36, 14195 Berlin, Germany.

Paul Kiler (P)

PK Perfumes, Menifee, California, United States of America.

Philipp Heretsch (P)

Leibniz Universität Hannover, Institut für Organische Chemie, Schneiderberg 1B, 30167 Hannover, Germany.

Classifications MeSH