Genomic Diversity across Candida auris Clinical Isolates Shapes Rapid Development of Antifungal Resistance


Journal

mBio
ISSN: 2150-7511
Titre abrégé: mBio
Pays: United States
ID NLM: 101519231

Informations de publication

Date de publication:
30 08 2022
Historique:
pubmed: 22 7 2022
medline: 3 9 2022
entrez: 21 7 2022
Statut: ppublish

Résumé

Antifungal drug resistance and tolerance pose a serious threat to global public health. In the human fungal pathogen, Candida auris, resistance to triazole, polyene, and echinocandin antifungals is rising, resulting in multidrug resistant isolates. Here, we use genome analysis and

Identifiants

pubmed: 35862787
doi: 10.1128/mbio.00842-22
pmc: PMC9426540
doi:

Substances chimiques

Antifungal Agents 0
Fluconazole 8VZV102JFY

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0084222

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI143689
Pays : United States

Commentaires et corrections

Type : CommentIn

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Auteurs

Laura S Burrack (LS)

Gustavus Adolphus College, Department of Biology, Saint Peter, Minnesota, USA.
University of Minnesotagrid.17635.36, Department of Microbiology and Immunology, Minneapolis, Minnesota, USA.

Robert T Todd (RT)

University of Minnesotagrid.17635.36, Department of Microbiology and Immunology, Minneapolis, Minnesota, USA.

Natthapon Soisangwan (N)

University of Minnesotagrid.17635.36, Department of Microbiology and Immunology, Minneapolis, Minnesota, USA.

Nathan P Wiederhold (NP)

University of Texas Health Science Center at San Antonio, Department of Pathology and Laboratory Medicine, Fungus Testing Laboratory, San Antonio, Texas, USA.

Anna Selmecki (A)

University of Minnesotagrid.17635.36, Department of Microbiology and Immunology, Minneapolis, Minnesota, USA.

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Classifications MeSH