The Role of Serial Radiographs in Diagnosing Diabetic Foot Bone Osteomyelitis.

Diabetic foot Magnetic resonance imaging Osteomyelitis Radiography

Journal

Mediterranean journal of hematology and infectious diseases
ISSN: 2035-3006
Titre abrégé: Mediterr J Hematol Infect Dis
Pays: Italy
ID NLM: 101530512

Informations de publication

Date de publication:
2022
Historique:
received: 24 03 2022
accepted: 17 06 2022
entrez: 22 7 2022
pubmed: 23 7 2022
medline: 23 7 2022
Statut: epublish

Résumé

Diagnosing diabetes-related foot osteomyelitis is sometimes a challenge for clinicians since it may occur without local or systemic signs of infection. Thus, the primary purpose of this article was to evaluate the role of progressive radiographic changes in diagnosing diabetic foot osteomyelitis. A retrospective review of databases of our Institution was performed to identify all long-standing diabetic foot patients who underwent two radiographic examinations spaced no more than five weeks apart and a subsequent magnetic resonance (MR) examination from November 2015 to November 2020. A total of 46 patients (32 men, 14 women; mean age, 57.3 years) were identified. serial radiographs showed 89% sensitivity, 38% specificity, 80% diagnostic accuracy, 87% positive predictive value (PPV), 43% negative predictive value (NPV) to diagnose osteomyelitis (P value < 0,05). Bone destruction was the most reliable radiographic sign with 89% sensitivity, 88% specificity, 89% diagnostic accuracy, 97% PPV, 64% NPV (P value < 0,05). Progressive bony changes detected by serial radiographs are a useful tool to diagnose diabetic foot osteomyelitis.

Sections du résumé

Background and Objective UNASSIGNED
Diagnosing diabetes-related foot osteomyelitis is sometimes a challenge for clinicians since it may occur without local or systemic signs of infection. Thus, the primary purpose of this article was to evaluate the role of progressive radiographic changes in diagnosing diabetic foot osteomyelitis.
Materials and Methods UNASSIGNED
A retrospective review of databases of our Institution was performed to identify all long-standing diabetic foot patients who underwent two radiographic examinations spaced no more than five weeks apart and a subsequent magnetic resonance (MR) examination from November 2015 to November 2020. A total of 46 patients (32 men, 14 women; mean age, 57.3 years) were identified.
Results UNASSIGNED
serial radiographs showed 89% sensitivity, 38% specificity, 80% diagnostic accuracy, 87% positive predictive value (PPV), 43% negative predictive value (NPV) to diagnose osteomyelitis (P value < 0,05). Bone destruction was the most reliable radiographic sign with 89% sensitivity, 88% specificity, 89% diagnostic accuracy, 97% PPV, 64% NPV (P value < 0,05).
Conclusion UNASSIGNED
Progressive bony changes detected by serial radiographs are a useful tool to diagnose diabetic foot osteomyelitis.

Identifiants

pubmed: 35865396
doi: 10.4084/MJHID.2022.055
pii: mjhid-14-1-e2022055
pmc: PMC9266704
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e2022055

Déclaration de conflit d'intérêts

Competing interests: The authors declare no conflict of Interest.

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Auteurs

Antonio Leone (A)

Department of Radiological and Hematological Sciences, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Largo A. Gemelli 1, 00168 Rome, Italy.

Nicola Carlo Bianco (NC)

Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Largo A. Gemelli 1, 00168 Rome, Italy.

Giulia D'Ambra (G)

Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Largo A. Gemelli 1, 00168 Rome, Italy.

Salvatore Lucchesi (S)

Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Largo A. Gemelli 1, 00168 Rome, Italy.

Elisa La Rosa (E)

Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Largo A. Gemelli 1, 00168 Rome, Italy.

Amato Infante (A)

Department of Radiological and Hematological Sciences, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Largo A. Gemelli 1, 00168 Rome, Italy.

Daniele Perla (D)

Department of Radiological and Hematological Sciences, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Largo A. Gemelli 1, 00168 Rome, Italy.

Consolato Gullì (C)

Department of Radiological and Hematological Sciences, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Largo A. Gemelli 1, 00168 Rome, Italy.

Classifications MeSH