The Bigger the Better? Analysis of Surgical Complications and Outcome of the Retrosigmoid Approach in 449 Oncological Cases.

neurooncology operative technique retrosigmoid approach skull base surgery surgical technical improvement

Journal

Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867

Informations de publication

Date de publication:
2022
Historique:
received: 07 05 2022
accepted: 27 05 2022
entrez: 22 7 2022
pubmed: 23 7 2022
medline: 23 7 2022
Statut: epublish

Résumé

Exposure of the posterior skull base and the cerebellopontine angle is challenging due to important neurovascular structures. The retrosigmoid approach (RSA) has become the standard method used in surgery. We report our experiences with RSAs regarding technical obstacles, complications, and approach-related outcomes. We performed a retrospective chart review at a tertiary neurosurgical center between January 2007 and September 2020. We included all patients undergoing surgery for oncologic lesions through RSAs, concentrating on surgical technique, postoperative outcome, and complications. A total of 449 RSAs were included. The median age at the time of surgery was 58 years; 168 (37.4%) were male and 281 (62.6%) were female. The median approach surface was 7.8 cm Tumor volume has an important impact on preoperative symptoms as well as on postoperative complications. Although the extent of the craniotomy barely missed significance regarding GTR, a correlation can be assumed. Thus, the extent of craniotomy should be taken into presurgical consideration, especially in the case of postoperative CSF leaks. Regarding vestibular schwannomas, craniotomy size plays an important role in achieving satisfactory oncological outcomes. Different approaches should be selected where necessary regarding superior resection rates.

Identifiants

pubmed: 35865465
doi: 10.3389/fonc.2022.938703
pmc: PMC9294506
doi:

Types de publication

Journal Article

Langues

eng

Pagination

938703

Informations de copyright

Copyright © 2022 Aftahy, Jörger, Hillebrand, Harder, Wiestler, Bernhardt, Combs, Meyer, Negwer and Gempt.

Déclaration de conflit d'intérêts

JG and BM work as consultants for Brainlab (Brainlab AG, Feldkirchen). In addition, BM works as a consultant for Medtronic, Spineart, Icotec, Relievant, and DePuy/Synthes. In these firms, BM acts as a member of the advisory board. Furthermore, BM reports a financial relationship with Medtronic, Ulrich Medical, Brainlab, Spineart, Icotec, Relievant, and DePuy/Synthes. He received personal fees and research grants for clinical studies from Medtronic, Ulrich Medical, Brainlab, Icotec, and Relievant. All this happened independently of the submitted work. BM holds royalties/patents for Spineart. All named potential conflicts of interest are unrelated to this study. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Amir Kaywan Aftahy (AK)

School of Medicine, Technical University Munich, Department of Neurosurgery, Klinikum rechts der Isar, Munich, Germany.

Ann-Kathrin Jörger (AK)

School of Medicine, Technical University Munich, Department of Neurosurgery, Klinikum rechts der Isar, Munich, Germany.

Sandra Hillebrand (S)

School of Medicine, Technical University Munich, Department of Neurosurgery, Klinikum rechts der Isar, Munich, Germany.

Felix N Harder (FN)

School of Medicine, Technical University Munich, Department of Radiology, Klinikum rechts der Isar, Munich, Germany.

Benedikt Wiestler (B)

School of Medicine, Technical University Munich, Department of Neuroradiology, Klinikum rechts der Isar, Munich, Germany.

Denise Bernhardt (D)

School of Medicine, Technical University Munich, Department of Radiation Oncology, Klinikum rechts der Isar, Munich, Germany.
German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.

Stephanie E Combs (SE)

School of Medicine, Technical University Munich, Department of Radiation Oncology, Klinikum rechts der Isar, Munich, Germany.
German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.
Institute of Innovative Radiotherapy (iRT), Department of Radiation Sciences (DRS), Helmholtz Zentrum Munich, Munich, Germany.

Bernhard Meyer (B)

School of Medicine, Technical University Munich, Department of Neurosurgery, Klinikum rechts der Isar, Munich, Germany.

Chiara Negwer (C)

School of Medicine, Technical University Munich, Department of Neurosurgery, Klinikum rechts der Isar, Munich, Germany.

Jens Gempt (J)

School of Medicine, Technical University Munich, Department of Neurosurgery, Klinikum rechts der Isar, Munich, Germany.

Classifications MeSH